Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Daniel J, Leong"'
Publikováno v:
Journal of Orthopaedic Translation, Vol 9, Iss C, Pp 69-75 (2017)
Tendon injuries are significant clinical problems. Current treatments often result in incomplete repair or healing, which may lead to reduced function and rupture. Stem cell-based therapy is a promising intervention for tendon repair. In this article
Externí odkaz:
https://doaj.org/article/15091df6a4f14b4d86543a85d9519a8b
Autor:
Daniel J. Leong, Marwa Choudhury, Regina Hanstein, David M. Hirsh, Sun Jin Kim, Robert J. Majeska, Mitchell B. Schaffler, John A. Hardin, David C. Spray, Mary B. Goldring, Neil J. Cobelli, Hui B. Sun
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-1 (2019)
Following publication of the original article [1], the authors reported an error in Figs. 2C and 5C.
Externí odkaz:
https://doaj.org/article/11a1159e8a124267a7828f7eb828308e
Autor:
Daniel J. Leong, Marwa Choudhury, David M. Hirsh, John A. Hardin, Neil J. Cobelli, Hui B. Sun
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 11, Pp 23063-23085 (2013)
Osteoarthritis (OA) is a degenerative joint disease and a leading cause of adult disability. There is no cure for OA, and no effective treatments which arrest or slow its progression. Current pharmacologic treatments such as analgesics may improve pa
Externí odkaz:
https://doaj.org/article/10c28af1b85d4b788f2ddf8c5f9fdde0
Autor:
Angela Wang, Daniel J. Leong, Zhiyong He, Lin Xu, Lidi Liu, Sun Jin Kim, David M. Hirsh, John A. Hardin, Neil J. Cobelli, Hui B. Sun
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 12, p 2065 (2016)
Procyanidins are a family of plant metabolites that have been suggested to mitigate osteoarthritis pathogenesis in mice. However, the underlying mechanism is largely unknown. This study aimed to determine whether procyanidins mitigate traumatic injur
Externí odkaz:
https://doaj.org/article/0ce63655496141f3a39d0653887588f0
Autor:
Calogera M Simonaro, Sylvain Sachot, Yi Ge, Xingxuan He, Victor A Deangelis, Efrat Eliyahu, Daniel J Leong, Hui B Sun, Jeffrey B Mason, Mark E Haskins, Dean W Richardson, Edward H Schuchman
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62715 (2013)
Acid ceramidase is required to maintain the metabolic balance of several important bioactive lipids, including ceramide, sphingosine and sphingosine-1-phosphate. Here we show that addition of recombinant acid ceramidase (rAC) to primary chondrocyte c
Externí odkaz:
https://doaj.org/article/940af73a6bb0409b9315b0fd6ccc0445
Autor:
Angela Wang Ilaltdinov, Hui B. Sun, Yubao Gong, Daniel J. Leong, Konrad I. Gruson, Deyou Zheng, Li Sun, David T. Fung
Publikováno v:
Annals of the New York Academy of SciencesReferences. 1490(1)
Tendinopathy is a common musculoskeletal disorder characterized by chronic low-grade inflammation and tissue degeneration. Tendons have poor innate healing ability and there is currently no cure for tendinopathy. Studies elucidating mechanisms underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f18ebb5d5bc6f38ceb0530a517220f3
https://pubmed.ncbi.nlm.nih.gov/32501571
https://pubmed.ncbi.nlm.nih.gov/32501571
Autor:
Jonathan Y Lee, Zuping Zhou, Peter J Taub, Melissa Ramcharan, Yonghui Li, Takintope Akinbiyi, Edward R Maharam, Daniel J Leong, Damien M Laudier, Takuya Ruike, Phillip J Torina, Mone Zaidi, Robert J Majeska, Mitchell B Schaffler, Evan L Flatow, Hui B Sun
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17531 (2011)
We characterized the differentiation of rat bone marrow-derived mesenchymal stem cells (BM-MSCs) into tenocyte-like cells in response to bone morphogenetic protein-12 (BMP-12). BM-MSCs were prepared from Sprague-Dawley rats and cultured as monolayers
Externí odkaz:
https://doaj.org/article/ae65fd77be85486589f50a62da92add4
Publikováno v:
Annals of the New York Academy of Sciences. 1410:57-67
Exosomes are nanovesicles secreted from cells that play key roles in intercellular communication. They carry unique content derived from parental cells and are capable of transferring this cargo between cells. The role and function of exosomes largel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddd2985e89c3080cfaa33006b10b6957
https://doi.org/10.1111/nyas.13469
https://doi.org/10.1111/nyas.13469
Publikováno v:
Journal of Orthopaedic Translation, Vol 9, Iss C, Pp 69-75 (2017)
Journal of Orthopaedic Translation
Journal of Orthopaedic Translation
Summary Tendon injuries are significant clinical problems. Current treatments often result in incomplete repair or healing, which may lead to reduced function and rupture. Stem cell-based therapy is a promising intervention for tendon repair. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d70d91cbb4bf6b7d5de074ceb4818e
http://www.sciencedirect.com/science/article/pii/S2214031X16302844
http://www.sciencedirect.com/science/article/pii/S2214031X16302844