Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Daniel J, Distefano"'
Autor:
Aimin Tang, Zhifeng Chen, Kara S. Cox, Hua-Poo Su, Cheryl Callahan, Arthur Fridman, Lan Zhang, Sangita B. Patel, Pedro J. Cejas, Ryan Swoyer, Sinoeun Touch, Michael P. Citron, Dhanasekaran Govindarajan, Bin Luo, Michael Eddins, John C. Reid, Stephen M. Soisson, Jennifer Galli, Dai Wang, Zhiyun Wen, Gwendolyn J. Heidecker, Danilo R. Casimiro, Daniel J. DiStefano, Kalpit A. Vora
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Respiratory syncytial virus (RSV) is a leading cause of infant hospitalization. Here, the authors isolate a human monoclonal antibody that binds to a highly conserved epitope on the RSV fusion protein, neutralizes RSV A and B subtypes equipotently an
Externí odkaz:
https://doaj.org/article/353ee58e3241465cbd5aae22b7984ad3
Autor:
Hualin Li, Cheryl Callahan, Michael Citron, Zhiyun Wen, Sinoeun Touch, Morgan A Monslow, Kara S Cox, Daniel J DiStefano, Kalpit A Vora, Andrew Bett, Amy Espeseth
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187642 (2017)
Respiratory syncytial virus (RSV) is a leading cause of serious lower respiratory tract disease in young children and older adults throughout the world. Prevention of severe RSV disease through active immunization is optimal but no RSV vaccine has be
Externí odkaz:
https://doaj.org/article/e018d3e0e3ee41dbb4b9118e502bda6f
Autor:
Michael P. Citron, Zhiyun Wen, Nickita Mehta, Galit Alter, Amy S. Espeseth, Daniel J. DiStefano, Jishnu Das, Sinoeun Touch, Cheryl Callahan, Jeffrey R. Sachs, Tomer Zohar, Paloma Cejas, Andrew J. Bett, Anush Devadhasan, Douglas A. Lauffenburger, Wiktor Karpinski
Publikováno v:
SSRN Electronic Journal.
Respiratory syncytial virus (RSV) infection is a major cause of severe respiratory illness in both young infants and the elderly. While antibodies represent key correlates of protection, the antibody mechanisms remain poorly understood. Emerging data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6719f9cab23b02199c01f08b1e53e65
https://doi.org/10.2139/ssrn.3848108
https://doi.org/10.2139/ssrn.3848108
Autor:
Andrew J. Bett, Dai Wang, Zhiyun Wen, Andrew H. Latham, Lan Zhang, Kalpit A. Vora, Michael P. Citron, Jeffrey S. Smith, Marian E. Gindy, Christine A. Shaw, Joseph M. Antonello, Jessica A. Flynn, Ryan Swoyer, Cheryl Callahan, Giuseppe Ciaramella, Paloma Cejas, Daniel J. DiStefano, Kapil Bahl, Daniel C. Freed, Kara S. Cox, Gregory O’ Donnell, Amy S. Espeseth, Sinoeun Touch, Jennifer D. Galli, Daria J. Hazuda
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 5, Iss 1, Pp 1-14 (2020)
npj Vaccines, Vol 5, Iss 1, Pp 1-14 (2020)
The RSV Fusion (F) protein is a target for neutralizing antibody responses and is a focus for vaccine discovery; however, the process of RSV entry requires F to adopt a metastable prefusion form and transition to a more stable postfusion form, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f124a59770591309d57e7f3b9697da6
http://europepmc.org/articles/PMC7021756
http://europepmc.org/articles/PMC7021756
Autor:
Tomer Zohar, Jeff C. Hsiao, Nickita Mehta, Jishnu Das, Anush Devadhasan, Wiktor Karpinski, Cheryl Callahan, Michael P. Citron, Daniel J. DiStefano, Sinoeun Touch, Zhiyun Wen, Jeffrey R. Sachs, Pedro J. Cejas, Amy S. Espeseth, Douglas A. Lauffenburger, Andrew J. Bett, Galit Alter
Publikováno v:
Cell Host & Microbe. 30:41-52.e5
Respiratory syncytial virus (RSV) infection is a major cause of respiratory illness in infants and the elderly. Although several vaccines have been developed, none have succeeded in part due to our incomplete understanding of the correlates of immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8edc295d44acedf99d0569b27323bf
https://doi.org/10.1016/j.chom.2021.11.006
https://doi.org/10.1016/j.chom.2021.11.006
Autor:
Zhiyun Wen, Amy S. Espeseth, Lan Zhang, Kalpit A. Vora, Daniel J. DiStefano, Mike Citron, Andrew J. Bett
Publikováno v:
Journal of virological methods. 263
Viral plaque assays are important tools in the development and evaluation of new antiviral drugs or vaccines in both preclinical and clinical research. While plaque assays are the standard tools to measure infectious virus, the methodology is time-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46eb07c468e9f9aab852c28e6571a5dd
https://pubmed.ncbi.nlm.nih.gov/30381239
https://pubmed.ncbi.nlm.nih.gov/30381239
Autor:
Benjamin J. Doranz, Hao Yan, Melanie Horton, Aimin Tang, Sheri Dubey, Danilo R. Casimiro, Zhifeng Chen, Daniel J. DiStefano, Kalpit A. Vora, Xin-Min Wang, Rachel H. Fong, Kara S. Cox, Andrew Ettenger
Publikováno v:
mAbs
Monitoring antigen-specific memory B cells and the antibodies they encode is important for understanding the specificity, breadth and duration of immune response to an infection or vaccination. The antibodies isolated could further help design vaccin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768646b2b83f97308ac4310de46c89e1
https://doi.org/10.1080/19420862.2015.1109757
https://doi.org/10.1080/19420862.2015.1109757
Autor:
Amy S. Espeseth, Gwendolyn J. Heidecker, Lani Indrawati, Xiaoping Liang, Dhanasekaran Govindarajan, Michael P. Citron, Cheryl Callahan, Biao He, Shannon Phan, Daniel J. DiStefano, Sheri Dubey, Dai Wang
Human respiratory syncytial virus (RSV) is a common cause of severe respiratory disease among infants, immunocompromised individuals, and the elderly. No licensed vaccine is currently available. In this study, we evaluated two parainfluenza virus 5 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1eb4dff123f198644800676d0b05cdc
https://europepmc.org/articles/PMC5432884/
https://europepmc.org/articles/PMC5432884/
Autor:
Michael P. Citron, Daniel J. DiStefano, Kara S. Cox, Cheryl Callahan, Zhiyun Wen, Hualin Li, Morgan A. Monslow, Andrew J. Bett, Sinoeun Touch, Amy S. Espeseth, Kalpit A. Vora
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187642 (2017)
PLoS ONE
PLoS ONE
Respiratory syncytial virus (RSV) is a leading cause of serious lower respiratory tract disease in young children and older adults throughout the world. Prevention of severe RSV disease through active immunization is optimal but no RSV vaccine has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55eea946220e046c52651e36763f6868
http://europepmc.org/articles/PMC5679537?pdf=render
http://europepmc.org/articles/PMC5679537?pdf=render
Autor:
Jay A. Grobler, Meizhen Feng, Yuan Li, Yves Ducharme, Jean-Pierre Falgueyret, Bernard Cote, Youwei Yan, Louis-Charles Campeau, Ernest Asante-Appiah, Ming-Tain Lai, Jason Burch, Marc V. Witmer, Daria J. Hazuda, Michael D. Miller, Nancy A. Sachs, Elizabeth Cauchon, Paul Tawa, Daniel J. DiStefano, Meiqing Lu
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:1652-1663
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are a mainstay of therapy for treating human immunodeficiency type 1 virus (HIV-1)-infected patients. MK-1439 is a novel NNRTI with a 50% inhibitory concentration (IC 50 ) of 12, 9.7, and 9.7 nM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::031e80e91b45808e18f50cd354a2ad72
https://doi.org/10.1128/aac.02403-13
https://doi.org/10.1128/aac.02403-13