Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Daniel I.R. Rose"'
Autor:
Kristen D. Nordham, Michael T. O’Brien, Piyush Joshi, Vittorio Maglione, Audra M. Foshage, Rachana Nitin, Miles R. Bryan, Aaron B. Bowman, Daniel I.R. Rose, Alba Di Pardo, Michael Aschner, Michael A. Uhouse, Ziyan Zhang
Publikováno v:
Hum Mol Genet
The molecular etiology linking the pathogenic mutations in the Huntingtin (Htt) gene with Huntington’s disease (HD) is unknown. Prior work suggests a role for Htt in neuronal autophagic function and mutant HTT protein disrupts autophagic cargo load
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46d6f3fe86524de9235aa52d0f452976
https://doi.org/10.1093/hmg/ddz209
https://doi.org/10.1093/hmg/ddz209
Publikováno v:
Journal of the American College of Cardiology. 79:1380
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::050d3deb7f1b54780be1cf1941caa082
https://doi.org/10.1016/s0735-1097(22)02371-3
https://doi.org/10.1016/s0735-1097(22)02371-3
Autor:
Michael Aschner, Aaron B. Bowman, Michael T. O’Brien, Michael A. Uhouse, Kristen D. Nordham, Miles R. Bryan, Daniel I.R. Rose, Piyush Joshi
Publikováno v:
NeuroToxicology. 64:185-194
In a recent study, we found that blocking the protein kinase ataxia telangiectasia mutated (ATM) with the small molecule inhibitor (SMI) KU-55933 can completely abrogate Mn-induced phosphorylation of p53 at serine 15 (p-p53) in human induced pluripot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a09957e0d510c8389b498ed2138bbcd
https://doi.org/10.1016/j.neuro.2017.07.026
https://doi.org/10.1016/j.neuro.2017.07.026
Autor:
Miles R. Bryan, Michael Aschner, Michael A. Uhouse, Michael T. O’Brien, Filipe Marques Gonçalves, Daniel I.R. Rose, Kristen D. Nordham, Rachana Nitin, Aaron B. Bowman, Piyush Joshi, Audra M. Foshage
Publikováno v:
Mol Neurobiol
Perturbations in insulin/IGF signaling and manganese (Mn(2+)) uptake and signaling have been separately reported in Huntington’s disease (HD) models. Insulin/IGF supplementation ameliorates HD phenotypes via upregulation of AKT, a known Mn(2+)-resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe5e312b86e57f887369d44158855a7
https://pubmed.ncbi.nlm.nih.gov/31797328
https://pubmed.ncbi.nlm.nih.gov/31797328