Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Daniel I. Ogborn"'
Autor:
Adeel Safdar, Konstantin Khrapko, James M. Flynn, Ayesha Saleem, Michael De Lisio, Adam P. W. Johnston, Yevgenya Kratysberg, Imtiaz A. Samjoo, Yu Kitaoka, Daniel I. Ogborn, Jonathan P. Little, Sandeep Raha, Gianni Parise, Mahmood Akhtar, Bart P. Hettinga, Glenn C. Rowe, Zoltan Arany, Tomas A. Prolla, Mark A. Tarnopolsky
Publikováno v:
Skeletal Muscle, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/e0ddedd4abac41088e921afb2a13b202
Autor:
Justin D Crane, Arkan Abadi, Bart P Hettinga, Daniel I Ogborn, Lauren G MacNeil, Gregory R Steinberg, Mark A Tarnopolsky
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81879 (2013)
Mitochondrial oxidative stress is a complex phenomenon that is inherently tied to energy provision and is implicated in many metabolic disorders. Exercise training increases mitochondrial oxidative capacity in skeletal muscle yet it remains unclear i
Externí odkaz:
https://doaj.org/article/361d3eb9c47642e8924a6b9375396e30
Autor:
Mahmood Akhtar, Daniel I. Ogborn, Mark A. Tarnopolsky, Gianni Parise, Adeel Safdar, Bryon R. McKay, Justin D. Crane
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 308:R734-R741
Mitochondrial dysfunction may contribute to age-associated muscle atrophy. Previous data has shown that resistance exercise (RE) increases mitochondrial gene expression and enzyme activity in older adults; however, the acute response to RE has not be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8da2f23e14b711550283bd51418e7b
https://doi.org/10.1152/ajpregu.00005.2014
https://doi.org/10.1152/ajpregu.00005.2014
Autor:
Lauren G. MacNeil, Nicholas J. Mocellin, Daniel I. Ogborn, Mark A. Tarnopolsky, Mats I. Nilsson, Yu Kitaoka
Publikováno v:
Molecular Genetics and Metabolism. 110:297-302
McArdle disease (MD) is a metabolic myopathy due to myophosphorylase deficiency, which leads to a severe limitation in the rate of adenosine triphosphate (ATP) resynthesis. Compensatory flux through the myoadenylate deaminasexanthine oxidase pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4885a21ea466eb55442e6744f447a6c5
https://doi.org/10.1016/j.ymgme.2013.06.022
https://doi.org/10.1016/j.ymgme.2013.06.022
Autor:
Mark A. Tarnopolsky, Daniel I. Ogborn, Bryon R. McKay, Gianni Parise, Jeff M. Baker, Kyle G. Toth
Publikováno v:
American Journal of Physiology-Cell Physiology. 304:C717-C728
Aging is associated with increased circulating interleukin-6 (IL-6) and a reduced myogenic capacity, marked by reduced muscle stem cell [satellite cell (SC)] activity. Although IL-6 is important for normal SC function, it is unclear whether elevated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9c42d30da901b3a441b0eef5cc3b9f
https://doi.org/10.1152/ajpcell.00305.2012
https://doi.org/10.1152/ajpcell.00305.2012
Publikováno v:
The FASEB Journal. 26:2509-2521
Human aging is accompanied by a progressive loss of muscle mass (sarcopenia). We tested the hypothesis that older males (OMs, 70±4 yr, n=9) would have a blunted myogenic response to a physiological stimulus compared to younger controls (21±3 yr, n=
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7a2110412db464e6c762f55eba6f9f
https://doi.org/10.1096/fj.11-198663
https://doi.org/10.1096/fj.11-198663
Autor:
Bart P. Hettinga, Jonathan P. Little, Konstantin Khrapko, Mahmood Akhtar, Adeel Safdar, Mark A. Tarnopolsky, Ayesha Saleem, Michael De Lisio, Yevgenya Kratysberg, Imtiaz A. Samjoo, James M. Flynn, Daniel I. Ogborn, Yu Kitaoka, Tomas A. Prolla, Gianni Parise, Glenn C. Rowe, Adam P. W. Johnston, Sandeep Raha, Zoltan Arany
Publikováno v:
Skeletal Muscle. 6
Background Human genetic disorders and transgenic mouse models have shown that mitochondrial DNA (mtDNA) mutations and telomere dysfunction instigate the aging process. Epidemiologically, exercise is associated with greater life expectancy and reduce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f46495aa3127a50b56e8bcefdd269c3
https://doi.org/10.1186/s13395-016-0075-9
https://doi.org/10.1186/s13395-016-0075-9
Autor:
Mahmood Akhtar, Tomas A. Prolla, Mark A. Tarnopolsky, Jacqueline M. Bourgeois, Nicholas J. Mocellin, Simon Melov, Gregory C. Kujoth, Bart P. Hettinga, Daniel I. Ogborn, James E. Thompson, Jonathan P. Little, Adeel Safdar
Publikováno v:
Proceedings of the National Academy of Sciences. 108:4135-4140
A causal role for mitochondrial DNA (mtDNA) mutagenesis in mammalian aging is supported by recent studies demonstrating that the mtDNA mutator mouse, harboring a defect in the proofreading-exonuclease activity of mitochondrial polymerase gamma, exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3cd35a7aa30a67e708bc7650008df8e
https://doi.org/10.1073/pnas.1019581108
https://doi.org/10.1073/pnas.1019581108
Autor:
Phillip F. Gardiner, Daniel I. Ogborn
Publikováno v:
Muscle & Nerve. 41:385-391
Muscle-derived neurotrophins are thought to contribute to the adaptation of skeletal muscle to exercise, but the effects of brief exercise interventions on BDNF, NT-4/5, and trkB are not understood. RNA was extracted for RT-PCR from soleus and medial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::397535b1b26a7015309ff801ee0f0af7
https://doi.org/10.1002/mus.21503
https://doi.org/10.1002/mus.21503
The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 307(6)
Endoplasmic reticulum (ER) stress results from an imbalance between the abundance of synthesized proteins and the folding capacity of the ER. In response, the unfolded protein response (UPR) attempts to restore ER function by attenuating protein synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d607ff442401cb15809afb4cfe71f69c
https://pubmed.ncbi.nlm.nih.gov/25009220
https://pubmed.ncbi.nlm.nih.gov/25009220