Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Daniel Hymon"'
Autor:
Mihajlo Novakovic, Daniel Hymon, Gregory L. Olsen, Lucio Frydman, György Pintér, Harald Schwalbe, Boris Fürtig
Publikováno v:
Proc Natl Acad Sci U S A
NMR sensitivity-enhancement methods involving hyperpolarized water could be of importance for solution-state biophysical investigations. Hyperpolarized water (HyperW) can enhance the 1 H NMR signals of exchangeable sites by orders of magnitude over t
Autor:
Klara R. Mertinkus, J. Tassilo Grün, Nadide Altincekic, Jasleen Kaur Bains, Betül Ceylan, Jan-Peter Ferner, Lucio Frydman, Boris Fürtig, Martin Hengesbach, Katharina F. Hohmann, Daniel Hymon, Jihyun Kim, Božana Knezic, Mihajlo Novakovic, Andreas Oxenfarth, Stephen A. Peter, Nusrat S. Qureshi, Christian Richter, Tali Scherf, Andreas Schlundt, Robbin Schnieders, Harald Schwalbe, Elke Stirnal, Alexey Sudakov, Jennifer Vögele, Anna Wacker, Julia E. Weigand, Julia Wirmer-Bartoschek, Maria A. Wirtz Martin, Jens Wöhnert
Publikováno v:
Biomolecular NMR Assignments, 16
The ongoing pandemic of the respiratory disease COVID-19 is caused by the SARS-CoV-2 (SCoV2) virus. SCoV2 is a member of the Betacoronavirus genus. The 30 kb positive sense, single stranded RNA genome of SCoV2 features 5'- and 3'-genomic ends that ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f387aa7cf6d5f0b5a6907a6bb95fa8
https://hdl.handle.net/20.500.11850/534661
https://hdl.handle.net/20.500.11850/534661
Autor:
Brandts, Fatima Baker, Ibrahim H. Polat, Khalil Abou-El-Ardat, Islam Alshamleh, Marlyn Thoelken, Daniel Hymon, Andrea Gubas, Sebastian E. Koschade, Jonas B. Vischedyk, Manuel Kaulich, Harald Schwalbe, Shabnam Shaid, Christian H.
Publikováno v:
Cancers; Volume 13; Issue 23; Pages: 6142
Autophagy is an important survival mechanism that allows recycling of nutrients and removal of damaged organelles and has been shown to contribute to the proliferation of acute myeloid leukemia (AML) cells. However, little is known about the mechanis
Autor:
Fatima Baker, Ibrahim H. Polat, Khalil Abou-El-Ardat, Islam Alshamleh, Marlyn Thoelken, Daniel Hymon, Andrea Gubas, Sebastian E. Koschade, Jonas B. Vischedyk, Manuel Kaulich, Harald Schwalbe, Shabnam Shaid, Christian H. Brandts
Publikováno v:
Cancers
Cancers, Vol 13, Iss 6142, p 6142 (2021)
Cancers, Vol 13, Iss 6142, p 6142 (2021)
Simple Summary The importance of autophagy in leukemia progression and survival has been studied previously. However, little is known about the development of resistance mechanisms to autophagy inhibition in leukemia. Here, we present data on the mec
Autor:
Jennifer Vögele, Jasleen Kaur Bains, Sophie Marianne Korn, Tom Landgraf, Hendrik R. A. Jonker, Daniel Hymon, Robbin Schnieders, Daniel Mathieu, Sabrina Toews, Nadide Altincekic, Bozana Knezic, Katharina F. Hohmann, J Tassilo Grün, Julia Wirmer-Bartoschek, Frank Löhr, Elke Duchardt-Ferner, Anna Wacker, Kerstin Witt, Dennis J. Pyper, Alexey Sudakov, Jens Wöhnert, Boris Fürtig, Julia E. Weigand, Stephen A. Peter, Betül Ceylan, Harald Schwalbe, Oliver Binas, Martin Hengesbach, Elke Stirnal, Andreas Schlundt, Nusrat S. Qureshi, Christian Richter, Jan Ferner
Publikováno v:
Biomolecular Nmr Assignments
The stem-loop (SL1) is the 5'-terminal structural element within the single-stranded SARS-CoV-2 RNA genome. It is formed by nucleotides 7–33 and consists of two short helical segments interrupted by an asymmetric internal loop. This architecture is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca8d91e354fdc03948fa1f0e0e6af4a
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/63569
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/63569
Autor:
Harald Schwalbe, Jens Wöhnert, Boris Fürtig, Stephen A. Peter, Dennis J. Pyper, Alexey Sudakov, Frank Löhr, Betül Ceylan, Elke Duchardt-Ferner, Anna Wacker, Andreas Schlundt, Martin Hengesbach, Nusrat S. Qureshi, Bozana Knezic, Katharina F. Hohmann, Julia E. Weigand, Jennifer Vögele, Elke Stirnal, Jasleen Kaur Bains, J Tassilo Grün, Nadide Altincekic, Daniel Hymon, Julia Wirmer-Bartoschek, Jan Ferner, Christian Richter
Publikováno v:
Biomolecular Nmr Assignments
The SARS-CoV-2 virus is the cause of the respiratory disease COVID-19. As of today, therapeutic interventions in severe COVID-19 cases are still not available as no effective therapeutics have been developed so far. Despite the ongoing development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e453ee3ed308fffea71c1065f826a81
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/63659
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/63659
Autor:
Anna Wacker, Julia E Weigand, Sabine R Akabayov, Nadide Altincekic, Jasleen Kaur Bains, Elnaz Banijamali, Oliver Binas, Jesus Castillo-Martinez, Erhan Cetiner, Betül Ceylan, Liang-Yuan Chiu, Jesse Davila-Calderon, Karthikeyan Dhamotharan, Elke Duchardt-Ferner, Jan Ferner, Lucio Frydman, Boris Fürtig, José Gallego, J Tassilo Grün, Carolin Hacker, Christina Haddad, Martin Hähnke, Martin Hengesbach, Fabian Hiller, Katharina F Hohmann, Daniel Hymon, Vanessa de Jesus, Henry Jonker, Heiko Keller, Bozana Knezic, Tom Landgraf, Frank Löhr, Le Luo, Klara R Mertinkus, Christina Muhs, Mihajlo Novakovic, Andreas Oxenfarth, Martina Palomino-Schätzlein, Katja Petzold, Stephen A Peter, Dennis J Pyper, Nusrat S Qureshi, Magdalena Riad, Christian Richter, Krishna Saxena, Tatjana Schamber, Tali Scherf, Judith Schlagnitweit, Andreas Schlundt, Robbin Schnieders, Harald Schwalbe, Alvaro Simba-Lahuasi, Sridhar Sreeramulu, Elke Stirnal, Alexey Sudakov, Jan-Niklas Tants, Blanton S Tolbert, Jennifer Vögele, Lena Weiß, Julia Wirmer-Bartoschek, Maria A Wirtz Martin, Jens Wöhnert, Heidi Zetzsche
Publikováno v:
Nucleic Acids Research
The current pandemic situation caused by the Betacoronavirus SARS-CoV-2 (SCoV2) highlights the need for coordinated research to combat COVID-19. A particularly important aspect is the development of medication. In addition to viral proteins, structur
Autor:
Tatjana Schamber, Kamal Azzaoui, Nusrat S. Qureshi, Boris Fürtig, Oliver Binas, Jason N Martins, Marcel J. J. Blommers, Daniel Hymon, Alix Tröster, Jasleen Kaur Bains, Christian Richter, Harald Schwalbe, Elke Stirnal, Andreas Oxenfarth, Julia Wirmer-Bartoschek, Hannes Berg, Anna Wacker, Robbin Schnieders, Tom Landgraf, Vanessa de Jesus, Santosh Lakshmi Gande, Sridhar Sreeramulu, Thomas Biedenbänder, Maria Alexandra Wirtz Martin, Albrecht Eduard Völklein, Anna Niesteruk
Publikováno v:
ChemBioChem
Chembiochem
Chembiochem
We report here on the nuclear magnetic resonance (NMR) 19 F screening of 14 RNA targets with different secondary and tertiary structure to systematically assess druggability of RNAs. Our RNA targets include representative bacterial riboswitches that
Autor:
Martin Hengesbach, Jennifer Adam, Sridhar Sreeramulu, Maria Alexandra Wirtz Martin, Jan Ferner, Boris Fürtig, Dennis J. Pyper, Nadide Altincekic, Daniel Hymon, Robbin Schnieders, Ute Scheffer, Betül Ceylan, Klara R. Mertinkus, Marcel J. J. Blommers, Jasleen Kaur Bains, Kamal Azzaoui, Julia E. Weigand, Julia Wirmer-Bartoschek, Anna Niesteruk, Anna Wacker, Tobias Matzel, Christian Richter, Stephen A. Peter, J Tassilo Grün, Jason N Martins, Alix Tröster, Bozana Knezic, Katharina F. Hohmann, Michael W. Göbel, Harald Schwalbe, Hannes Berg, Alexey Sudakov, Elke Stirnal, Jens Wöhnert, Andreas Schlundt, Nusrat S. Qureshi, Jennifer Vögele
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International Ed. in English)
SARS‐CoV‐2 contains a positive single‐stranded RNA genome of approximately 30 000 nucleotides. Within this genome, 15 RNA elements were identified as conserved between SARS‐CoV and SARS‐CoV‐2. By nuclear magnetic resonance (NMR) spectrosc