Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Daniel Hwang"'
Autor:
Nestoras Karathanasis, Daniel Hwang, Vibol Heng, Rimal Abhimannyu, Phillip Slogoff-Sevilla, Gina Buchel, Victoria Frisbie, Peiyao Li, Dafni Kryoneriti, Isidore Rigoutsos
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 11, p e1010615 (2022)
The "replication crisis" is a methodological problem in which many scientific research findings have been difficult or impossible to replicate. Because the reproducibility of empirical results is an essential aspect of the scientific method, such fai
Externí odkaz:
https://doaj.org/article/40248b4e44854a57ad5531c5516e8273
SIRT1 inactivation switches reactive astrocytes to an antiinflammatory phenotype in CNS autoimmunity
Autor:
Weifeng Zhang, Dan Xiao, Xing Li, Yuan Zhang, Javad Rasouli, Giacomo Casella, Alexandra Boehm, Daniel Hwang, Larissa L.W. Ishikawa, Rodolfo Thome, Bogoljub Ciric, Mark T. Curtis, Abdolmohamad Rostami, Guang-Xian Zhang
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)
Astrocytes are highly heterogeneous in their phenotype and function, which contributes to CNS disease, repair, and aging; however, the molecular mechanism of their functional states remains largely unknown. Here, we show that activation of sirtuin 1
Externí odkaz:
https://doaj.org/article/6a88e9f7e5d74a7c842c4e33e2a93d55
Autor:
Giacomo Casella, Javad Rasouli, Rodolfo Thome, Hélène C. Descamps, Asrita Vattikonda, Larissa Ishikawa, Alexandra Boehm, Daniel Hwang, Weifeng Zhang, Dan Xiao, Jeongho Park, Guang-Xian Zhang, Jorge I. Alvarez, Abdolmohamad Rostami, Bogoljub Ciric
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Antigen (Ag)-specific tolerance induction by intravenous (i. v.) injection of high-dose auto-Ags has been explored for therapy of autoimmune diseases, including multiple sclerosis (MS). It is thought that the advantage of such Ag-specific therapy ove
Externí odkaz:
https://doaj.org/article/270b36e7c7d3452e82186e61202028fa
Autor:
R. Vivian Allahyari, Nicolette M. Heinsinger, Daniel Hwang, David A. Jaffe, Javad Rasouli, Stephanie Shiers, Samantha J. Thomas, Theodore J. Price, Abdolmohamad Rostami, Angelo C. Lepore
Publikováno v:
Cells, Vol 11, Iss 4, p 721 (2022)
There is growing appreciation for astrocyte heterogeneity both across and within central nervous system (CNS) regions, as well as between intact and diseased states. Recent work identified multiple astrocyte subpopulations in mature brain. Interestin
Externí odkaz:
https://doaj.org/article/f3c9b73e7f55416d9c08ca3be6b96d78
Autor:
Rodolfo Thomé, Jason N. Moore, Elisabeth R. Mari, Javad Rasouli, Daniel Hwang, Satoshi Yoshimura, Bogoljub Ciric, Guang-Xian Zhang, Abdolmohamad M. Rostami
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Peripheral tolerance to autoantigens is induced via suppression of self-reactive lymphocytes, stimulation of tolerogenic dendritic cells (DCs) and regulatory T (Treg) cells. Interleukin (IL)-27 induces tolerogenic DCs and Treg cells; however, it is n
Externí odkaz:
https://doaj.org/article/5a550a8a266c48f9aa32ed2386599983
Autor:
Mahesh Vaisnav, Chao Xing, Hung-Chih Ku, Daniel Hwang, Strahinja Stojadinovic, Alexander Pertsemlidis, John M Abrams
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104858 (2014)
Ionizing radiation is genotoxic to cells. Healthy tissue toxicity in patients and radiation resistance in tumors present common clinical challenges in delivering effective radiation therapies. Radiation response is a complex, polygenic trait with unk
Externí odkaz:
https://doaj.org/article/b74e4cc7325f4f069ec73f1ec1ef1e9c
Autor:
Mualla Ozcan, Zhen Guo, Carla Valenzuela Ripoll, Ahmed Diab, Antonino Picataggi, David Rawnsley, Aynaz Lotfinaghsh, Carmen Bergom, Jeff Szymanski, Daniel Hwang, Aarti Asnani, Mikhail Kosiborod, Jie Zheng, Robert J. Hayashi, Pamela K. Woodard, Attila Kovacs, Kenneth B. Margulies, Joel Schilling, Babak Razani, Abhinav Diwan, Ali Javaheri
Publikováno v:
Cell Metabolism.
Autor:
Ching-Hsuan Huang, Thu Bui, Daniel Hwang, Jeffry Shirai, Elena Austin, Martin Cohen, Timothy Gould, Timothy Larson, Igor Novosselov, Shirlee Tan, Edmund Seto
Over four thousand portable air cleaners (PACs) with high-efficiency particulate air (HEPA) filters were distributed by Public Health - Seattle & King County to homeless shelters during the COVID-19 pandemic. This study aimed to evaluate the real-wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8821abad1f6a47955814120cf0cfde7a
https://doi.org/10.1101/2023.01.20.23284493
https://doi.org/10.1101/2023.01.20.23284493
Autor:
Daniel Hwang, Larissa Lumi Watanabe Ishikawa, Maryam S. Seyedsadr, Elisabeth Mari, Ezgi Kasimoglu, Ziver Sahin, Alexandra Boehm, Soohwa Jang, Javad Rasouli, Courtney Vaccaro, Michael Gonzalez, Hakon Hakonarson, Abdolmohamad Rostami, Guang-Xian Zhang, Bogoljub Ciric
Publikováno v:
Blood advances. 6(23)
GATA-binding factor 1 (GATA1) is a transcription factor that governs the development and function of multiple hematopoietic cell lineages. GATA1 is expressed in hematopoietic stem and progenitor cells (HSPCs) and is essential for erythroid lineage co
Autor:
Ching-Hsuan Huang, Thu Bui, Daniel Hwang, Jeffry Shirai, Elena Austin, Martin Cohen, Timothy Gould, Timothy Larson, Igor Novosselov, Shirlee Tan, Julie Fox, Edmund Seto
Publikováno v:
Science of The Total Environment. :164402