Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Daniel Hui"'
Autor:
Daniel Hui, Eric Sanford, Kimberly Lorenz, Scott M Damrauer, Themistocles L Assimes, Christopher S Thom, Benjamin F Voight
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0298786 (2024)
An inverse correlation between stature and risk of coronary artery disease (CAD) has been observed in several epidemiologic studies, and recent Mendelian randomization (MR) experiments have suggested causal association. However, the extent to which t
Externí odkaz:
https://doaj.org/article/4c820088beb54a40ba027cdde983d34e
Autor:
David Zurowski, Samir Patel, Daniel Hui, Mignane Ka, Charles Hernandez, Andrea C. Love, Bo Lin, Andrea Moore, Leo Li-Ying Chan
Publikováno v:
SLAS Discovery, Vol 28, Iss 3, Pp 65-72 (2023)
Solid tumors account for approximately 90% of all adult human cancers. As such, the development of novel cellular therapies has become of increasing importance to target solid tumor malignancies, such as prostate, lung, breast, bladder, colon, and li
Externí odkaz:
https://doaj.org/article/ef887480d688432bbe77fa082a448b37
Autor:
Daniel Hui, Shadi Mehrabi, Alexandra E Quimby, Tingfang Chen, Sixing Chen, Joseph Park, Binglan Li, Regeneron Genetics Center, Penn Medicine Biobank, Michael J Ruckenstein, Daniel J Rader, Marylyn D Ritchie, Jason A Brant, Douglas J Epstein, Iain Mathieson
Publikováno v:
PLoS Genetics, Vol 19, Iss 1, p e1010584 (2023)
Loss or absence of hearing is common at both extremes of human lifespan, in the forms of congenital deafness and age-related hearing loss. While these are often studied separately, there is increasing evidence that their genetic basis is at least par
Externí odkaz:
https://doaj.org/article/ef78704e18c942e38c1ddce3d6bafdf6
Publikováno v:
BMC Genetics, Vol 18, Iss 1, Pp 1-5 (2017)
Abstract Background Inferring local ancestry in individuals of mixed ancestry has many applications, most notably in identifying disease-susceptible loci that vary among different ethnic groups. Many software packages are available for inferring loca
Externí odkaz:
https://doaj.org/article/a0f93158109f4b679949e1d4d38d86bc
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Externí odkaz:
https://doaj.org/article/b27c5c688b5a40f98a48ae87bda4af4d
Autor:
Vilija G Jokubaitis, Maria Pia Campagna, Omar Ibrahim, Jim Stankovich, Pavlina Kleinova, Fuencisla Matesanz, Daniel Hui, Sara Eichau, Mark Slee, Jeannette Lechner-Scott, Rodney Lea, Trevor J Kilpatrick, Tomas Kalincik, Philip L De Jager, Ashley Beecham, Jacob L McCauley, Bruce V Taylor, Steve Vucic, Louise Laverick, Karolina Vodehnalova, Maria-Isabel García-Sanchéz, Antonio Alcina, Anneke van der Walt, Eva Kubala Havrdova, Guillermo Izquierdo, Nikolaos Patsopoulos, Dana Horakova, Helmut Butzkueven
Publikováno v:
Brain. 146:2316-2331
Multiple sclerosis is a leading cause of neurological disability in adults. Heterogeneity in multiple sclerosis clinical presentation has posed a major challenge for identifying genetic variants associated with disease outcomes. To overcome this chal
Autor:
Daniel Hui, Eric Sanford, Kimberly Lorenz, Scott M. Damrauer, Themistocles L. Assimes, Christopher S. Thom, Benjamin F. Voight
Publikováno v:
medRxiv
An inverse correlation between stature and risk of coronary artery disease (CAD) has been observed in several epidemiologic studies, and recent Mendelian randomization (MR) experiments have suggested causal association. However, the extent to which t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcb5acc2e3b7e6461442c2edf9e203a
https://europepmc.org/articles/PMC10187353/
https://europepmc.org/articles/PMC10187353/
Autor:
Daniel Hui, Brenda Xiao, Ozan Dikilitas, Robert R. Freimuth, Marguerite R. Irvin, Gail P. Jarvik, Leah Kottyan, Iftikhar Kullo, Nita A. Limdi, Cong Liu, Yuan Luo, Bahram Namjou, Megan J. Puckelwartz, Daniel Schaid, Hemant Tiwari, Wei-Qi Wei, Shefali Verma, Dokyoon Kim, Marylyn D. Ritchie
Publikováno v:
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 28
Polygenic risk scores (PRS) have led to enthusiasm for precision medicine. However, it is well documented that PRS do not generalize across groups differing in ancestry or sample characteristics e.g., age. Quantifying performance of PRS across differ
Autor:
Karl Keat, Daniel Hui, Brenda Xiao, Yuki Bradford, Zinhle Cindi, Eric S. Daar, Roy Gulick, Sharon A. Riddler, Phumla Sinxadi, David W. Haas, Marylyn D. Ritchie
Publikováno v:
Biocomputing 2023.
Widespread availability of antiretroviral therapies (ART) for HIV-1 have generated considerable interest in understanding the pharmacogenomics of ART. In some individuals, ART has been associated with excessive weight gain, which disproportionately a
Autor:
Patrick M. A. Sleiman, QiPing Feng, Anastasia Lucas, Charles M. Stein, Daniel Hui, Wei-Qi Wei, Thomas J. Hoffmann, Neil Risch, Hakon Hakonarson, Jason E. Miller, Digna R. Velez Edwards, Elizabeth Theusch, Marisa W. Medina, Daniel J. Rader, Daniel J. Schaid, Iftikhar J. Kullo, Benjamin F. Voight, Yogasudha Veturi, Ronald M. Krauss, Scott M. Dudek, Anurag Verma, Marylyn D. Ritchie, Yuki Bradford
Publikováno v:
Nature genetics
Plasma lipids are known heritable risk factors for cardiovascular disease, but increasing evidence also supports shared genetics with diseases of other organ systems. We devised a comprehensive three-phase framework to identify novel lipid-associated