scBubbletree: computational approach for visualization of single cell RNA-seq data

Autor: Simo Kitanovski, Yingying Cao, Dimitris Ttoouli, Farnoush Farahpour, Jun Wang, Daniel Hoffmann

Publikováno v: BMC Bioinformatics, Vol 25, Iss 1, Pp 1-17 (2024)

Abstract Background Visualization approaches transform high-dimensional data from single cell RNA sequencing (scRNA-seq) experiments into two-dimensional plots that are used for analysis of cell relationships, and as a means of reporting biological i

Externí odkaz: https://doaj.org/article/685ce80f31a5476b80242a1eb9a592da

Natural chalcones elicit formation of specialized pro-resolving mediators and related 15-lipoxygenase products in human macrophages

Autor: Denis Séraphin, Christian Kretzer, Markus Werner, Pascal Richomme, Andreas Koeberle, Veronika Temml, Paul M. Jordan, Jean-Jacques Helesbeux, Daniela Schuster, Katharina P.L. Meyer, Robert Klaus Hofstetter, Guillaume Viault, Antonio Cala Peralta, Hermann Stuppner, Daniel Hoff, Oliver Werz

Publikováno v: Biochemical pharmacology. 195

Specialized pro-resolving mediators (SPMs) comprise lipid mediators (LMs) produced from polyunsaturated fatty acids (PUFAs) via stereoselective oxygenation particularly involving 12/15-lipoxygenases (LOXs). In contrast to pro-inflammatory LMs such as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8baf0cc99b4fbc5fbcb7fd425e09c4
https://pubmed.ncbi.nlm.nih.gov/34762841

Recurrence and tumor-related death after resection of hepatocellular carcinoma in patients with metabolic syndrome

Autor: Giammauro Berardi, Alessandro Cucchetti, Carlo Sposito, Francesca Ratti, Martina Nebbia, Daniel M. D’Souza, Franco Pascual, Epameinondas Dogeas, Samer Tohme, Alessandro Vitale, Francesco Enrico D’Amico, Remo Alessandris, Valentina Panetta, Ilaria Simonelli, Marco Colasanti, Nadia Russolillo, Amika Moro, Guido Fiorentini, Matteo Serenari, Fernando Rotellar, Giuseppe Zimitti, Simone Famularo, Tommy Ivanics, Felipe Gaviria Donando, Daniel Hoffman, Edwin Onkendi, Yasmin Essaji, Tommaso Giuliani, Santiago Lopez Ben, Celia Caula, Gianluca Rompianesi, Asmita Chopra, Mohammed Abu Hilal, Gonzalo Sapisochin, Guido Torzilli, Carlos Corvera, Adnan Alseidi, Scott Helton, Roberto I. Troisi, Kerri Simo, Claudius Conrad, Matteo Cescon, Sean Cleary, David Choon Hyuck Kwon, Alessandro Ferrero, Giuseppe Maria Ettorre, Umberto Cillo, David Geller, Daniel Cherqui, Pablo E. Serrano, Cristina Ferrone, Luca Aldrighetti, T. Peter Kingham, Vincenzo Mazzaferro

Publikováno v: JHEP Reports, Vol 6, Iss 7, Pp 101075- (2024)

Background & Aims: Metabolic syndrome (MS) is a growing epidemic and a risk factor for the development of hepatocellular carcinoma (HCC). This study investigated the long-term outcomes of liver resection (LR) for HCC in patients with MS. Rates, timin

Externí odkaz: https://doaj.org/article/9c506f3cd5f04669b524cfbeb3a2654c

How prices and income influence global patterns in saturated fat intake by age, sex and world region: a cross-sectional analysis of 160 countries

Autor: Albertino Damasceno, Cristina Palacios, Anoop Misra, Parvin Mirmiran, Nizal Sarrafzadegan, Simon Anderson, Ingibjorg Gunnarsdottir, Yanping Li, Anand Krishnan, Yu Chen, Alireza Esteghamati, Farshad Farzadfar, Giuseppe Grosso, Reza Malekzadeh, Sumathi Swaminathan, Patricio Lopez-Jaramillo, Noushin Mohammadifard, Jean-Michel Gaspoz, Pedro Marques-Vidal, Idris Guessous, Tal Shimony, Lital Keinan-Boker, Carukshi Arambepola, Antonia Trichopoulou, Marialaura Bonaccio, Simona Costanzo, Licia Iacoviello, Andrew Muhammad, Wen-Harn Pan, Manami Inoue, Peter Vollenweider, Luz Maria Sanchez-Romero, Carl Lachat, Demosthenes Panagiotakos, Sangita Sharma, Eva Roos, Milton Severo, Safiah Yusof, Nuno Lunet, Roya Kelishadi, Anuradha Khadilkar, Cho-il Kim, Veena Ekbote, Masoud Mirzaei, Inge Huybrechts, Lluis Serra-Majem, Anjum Memon, Aminul Haque, Katia Castetbon, Saeed Dastgiri, Julia Reedy, Abla M. Sibai, Xia Cao, Pascal Bovet, Pamela Abbott, Karen Charlton, Hsing-Yi Chang, Yasuhiro Matsumura, Yoonsu Cho, Puneet Misra, Morteza Abdollahi, Suad Al-Hooti, Anahita Houshiar-rad, Eda Koksal, Abdulrahman Musaiger, Gulden Pekcan, Sahar Zaghloul, Yves Martin-Prevel, Kyungwon Oh, Meei-Shyuan Lee, Sirje Vaask, Shu Wen Ng, Simon Forsyth, Dimitrios Trichopoulos, Erkki Vartiainen, Christian Haerpfer, Carla Lopes, Foong Ming Moy, Tor Strand, Mohammadreza Pakseresht, Yi Ma, Androniki Naska, Dorothy Gauci, Ibrahim Elmadfa, Wilbur Hadden, Hajah Masni Ibrahim, Lars Johansson, Hae-Jeung Lee, Nur Indrawaty Lipoeto, Balakrishna Nagalla, Stefka Petrova, Noppawan Piaseu, Laufey Steingrimsdottir, Lucjan Szponar, Holmfridur Thorgeirsdóttir, Inga Thorsdottir, Aida Turrini, Anna Waskiewicz, Gábor Zajkás, Harikumar Rachakulla, Heléne Enghardt Barbieri, Nattinee Jitnarin, Le Tran Ngoan, Jaana Lindström, Kalyana Sundram, Ranil Jayawardena, Irina Kovalskys, Noël Barengo, Zaleha Abdullah Mahdy, Maryam Hashemian, Duarte Torres, Angélica Ochoa, Pulani Lanerolle, Chandrashekar Janakiram, Fatemeh Vida Zohoori, Parvin Abedi, Suvi Virtanen, Amelia Ahles, Jacqueline N Yenerall, Mustafa Arici, Amy Luke, Suhad Abumweis, Mohannad Al Nsour, Iftikhar Alam, Nasser Al-Daghri, Shaun Sabico, alHamad Nawal Ai, Eman Alissa, Sameer Al-Zenki, Karim Anzid, Joanne Arsenault Hacettepe, Renzo Asciak, Lajos Biró, Juan Rivera Dommarco, Daniel Illescas-Zarate, Sonia Rodriguez Ramirez, Ivonne Ramirez Silva, Per Bergman, Anna Karin Lindroos, Jessica Petrelius Sipinen, Sesikeran Boindala, Mauricio T. Caballero, FNeville Calleja, Mario Capanzana, Jan Carmikle, Michelle Castro, Corazon Cerdena, Shashi Chiplonkar, Khun-Aik Chuah, IRCCS INM Neuromed, Stefaan De Henauw, Karin DeRidder, Eric Ding, Rokiah Don, Charmaine Duante, Vesselka Duleva, Samuel Duran Aguero, Jalila El Ati, Alison Eldridge, Tatyana El-kour, Laetitia Nikiema, Zohreh Etemad, Fariza Fadzil, Mei Fen Chan, Anne Fernandez, Dulitha Fernando, Regina Fisberg, Edna Gamboa Delgado, J Brahmam Ginnela, Aida Hadziomeragic, Jemal Haidar Ali, Rubina Hakeem, Rajkumar Hemalatha, Avula Laxmaiah, Indrapal Meshram, Nimmathota Arlappa, Sigrun Henjum, Hristo Hinkov, Zaiton Hjdaud, Daniel Hoffman, Beth Hopping, Shu-Yi Hung Yao-Te Hsieh, Nahla Chawkat Hwalla, Nayu Ikeda, Olof Jonsdottir, Rajesh Jeewon, Ola Kally, Mirnalini Kandiah, Tilakavati Karupaiah, Rebecca Goldsmith, Jurgen Konig, Liisa Korkalo, Riitta Freese, Jeremy Koster, Herculina Kruger, Rebecca Kuriyan-Raj, Sanghui Kweon, Sihyun Park, Yuen Lai, Indu Waidyatilaka, Catherine Leclercq, J Lennert Veerman, Lydia Lera Marques, Annie Ling, Widjaja Lukito, Elisabette Lupotto, Stefania Sette, Raffaela Piccinelli, Wan Manan, Dirce Marchioni, Angie Mathee, Paramita Mazumdar, Gert Mensink, Alexa Meyer, Claudette Mitchell, David Balfour, Moses Mwangi, Maryam Maghroun, Fatemeh Mohammadi-Nasrabadi, Zalilah Mohd Shariff, Elizabeth Mwaniki, Jannicke Myhre, Augustin Nawidimbasba Zeba, Sina Noshad, Marga Ocke, Jillian Odenkirk, Mariana Oleas, Sonia Olivares, Johana Ortiz-Ulloa, Johanna Otero, Rajendra Parajuli, Luz Posada, Farhad Pourfarzi, Alan Martin Preston, Ingrid Rached, Ali Reza Rahbar, Colin Rehm, Makiko Sekiyama, Rusidah Selamat, Khadijah Shamsuddin, Harri Sinkko, Milton Fabian Suarez-Ortegon, Elzbieta Sygnowska, Maria Szabo, Ilse Khouw, Swee Ai Ng, Heli Tapanainen FrieslandCampina, Reema Tayyem, Bemnet Tedla, Coline van Oosterhout, Marieke Vossenaar, Eva Warensjo Lemming, Lothar Wieler, Mabel Yap, Maria Elisa Zapata, Khairul Zarina, Zipporah Bukania, Yeri Kombe, Julie Long, K. Michael Hambidge, Tshilenge S. Diba, Umber S. Khan, Gabriela Tejeda, Cornelia Tudorie, Anca Nicolau, Amanda de Moura Souza, Alan de Brauw, Mourad Moursi, Alicia Rovirosa, Carol Henry, Getahun Ersino, Gordon Zello, Chanthaly Luangphaxay, Daovieng Douangvichit, Latsamy Siengsounthone, Christine Hotz, Constance Rybak, Corina Aurelia Zugravu, Donka Baykova, Elizabeth Yakes-Jimenez, Gudrun B. Keding, Lydiah M. Waswa, Irmgard Jordan, J.V. Meenakshi, Laila Eleraky, Wolfgang Stuetz, Lalka Rangelova, Lilian Aluso, Julia Boedecker, Francis Oduor, Tamene Taye Asayehu, Veronika Janská, Ward Siamusantu, Ken Brown

Publikováno v: BMJ Open, Vol 14, Iss 1 (2024)

Objective When considering proposals to improve diets, it is important to understand how factors like price and income can affect saturated fat (SF) intake and demand. In this study, we examine and estimate the influence of price and income on intake

Externí odkaz: https://doaj.org/article/8b48541bb73243c99cbe7060b3a53989

Inadequate Lymph Node Yield: An Inadequate Indication for Adjuvant Chemotherapy in Stage II Colon Cancer

Autor: Alan Zambeli-Ljepović, MD, MHS, Daniel Hoffman, MD, Katherine E. Barnes, BS, Fernanda Romero-Hernandez, MD, Amir Ashraf Ganjouei, MD, MPH, Mohamed A. Adam, MD, Ankit Sarin, MD, MHA

Publikováno v: Annals of Surgery Open, Vol 4, Iss 4, p e338 (2023)

Background:. Optimal therapy for stage II colon cancer remains unclear, and national guidelines recommend “consideration” of adjuvant chemotherapy (ACT) in the presence of high-risk features, including inadequate lymph node yield (LNY,

Externí odkaz: https://doaj.org/article/6fdc21fe074f4bc7b9df3f25e49754d1