Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Daniel Hinkerohe"'
Autor:
Zahra Moinfar, Hannes Dambach, Daniel Hinkerohe, Nora Prochnow, Eckart Förster, Pedro M. Faustmann, Claus G. Haase, Fatme Seval Ismail
Publikováno v:
Journal of Neuro-Oncology
Gap junctions (GJs) in astrocytes and glioma cells are important channels for cell-to-cell communication that contribute to homo- and heterocellular coupling. According to recent studies, heterocellular gap-junctional communication (H-GJC) between gl
Autor:
Andreas Schoebel, Pedro M. Faustmann, Georg Zoidl, Dirk Smikalla, Daniel Hinkerohe, Uwe Schlegel, Claus G. Haase, Aiden Haghikia
Publikováno v:
Brain Research. 1329:45-54
We analyzed the effect of dexamethasone on gram-negative bacteria derived lipopolysaccharide (LPS) induced inflammation in astroglial/microglial co-cultures. At the cellular level the microglial phenotype converted to an activated type after LPS incu
Autor:
Pauline Lafenêtre, Daniel Hinkerohe, Aiden Haghikia, Kerstin Ladage, Rolf Dermietzel, Pedro M. Faustmann, Arash Haghikia, Claus G. Haase, Dirk Smikalla
Publikováno v:
Journal of Neuro-Oncology. 86:143-152
Human gliomas are the most common class of brain neoplasm. In order to better characterize their response to inflammation, we evaluated the influence of tumor necrosis factor alpha (TNF-alpha) on the coupling behaviour and the membrane resting potent
Autor:
Katharina Heupel, Dirk Smikalla, Aiden Haghikia, Claus G. Haase, Rolf Dermietzel, Daniel Hinkerohe, Pedro M. Faustmann
Publikováno v:
Glia. 52:85-97
Cytokines play an important role in the onset, regulation, and propagation of immune and inflammatory responses within the central nervous system (CNS). The main source of cytokines in the CNS are microglial cells. Under inflammatory conditions, micr
Publikováno v:
Journal of Clinical Neuroscience. 20:619-621
We present a 66-year-old female patient with a high cervical intramedullary metastasis from a malignant mixed Muellerian tumour (MMMT; carcinosarcoma) with concomitant syringomyelia. She was admitted to our clinic with symptoms of cervical myelopathy
Autor:
Zahra Moinfar, Daniel Hinkerohe, Martin N. Stienen, Nora Prochnow, Pedro M. Faustmann, Claus G. Haase, Andreas Hufnagel, Hannes Dambach
Publikováno v:
Epilepsia. 55(1)
Summary Purpose The contribution of glial cells, mainly astrocytes and microglia, to the pathophysiology of epilepsy is increasingly appreciated. Glia play a pivotal role in the initiation and maintenance of the central nervous system (CNS) immune re
Autor:
Daniel Hinkerohe, Uwe Schlegel, Carola Meier, Pedro M. Faustmann, Aiden Haghikia, Dörte Wolfkühler
Publikováno v:
Journal of neuro-oncology. 103(3)
Similar to astrocytes, glioma cells form a well-coupled syncytium via gap junctions. This can be influenced, for example, by activated microglia, the main inflammatory cell population within the central nervous system (CNS). Under pathological condit
Autor:
Katharina Heupel, Patrick Vollmar, Rolf Dermietzel, Kerstin Ladage, Daniel Hinkerohe, Aiden Haghikia, Pedro M. Faustmann
Publikováno v:
Journal of neuroscience research. 86(8)
There is accumulating evidence that epileptic activity is accompanied by inflammatory processes. In the present study, we evaluated the effect of levetiracetam (Keppra), an anticonvulsant drug with decisive antiepileptic features, with regard to its
Publikováno v:
Journal of the Neurological Sciences. 333:e372-e373
Autor:
Dominika Szlachta, Dorothee Krause, Sabine Romberg, Rolf Dermietzel, Pedro M. Faustmann, Daniel Hinkerohe, Dirk Smikalla, Claus G. Haase
Publikováno v:
Glia. 42(2)
Under inflammatory conditions, activated microglia are capable of producing proinflammatory cytokines that are reported to influence cell-to-cell communication. The present study was performed to evaluate the influence of microglial activation on the