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Autor:
Yousuke Yamada, Bruce J. Melancon, Zixiu Xiang, Katherine E. Crocker, Colleen M. Niswender, Craig W. Lindsley, P. Jeffrey Conn, Kristen Gilliland, Alice L. Rodriguez, Matthew T. Loch, Michael L. Schulte, Daniel Haymer
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 50:128342
This letter describes synthesis and evaluation of two series of dual mGlu2/mGlu3 positive allosteric modulators with moderate mGlu3 potency and robust mGlu2 potency in thallium flux assays. These compounds were profiled their ability to modulate mGlu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ec84e58e6cc03d5b185dec786f3488
https://doi.org/10.1016/j.bmcl.2021.128342
https://doi.org/10.1016/j.bmcl.2021.128342
