Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Daniel Hasche"'
Autor:
Melinda Ahmels, Filipe C. Mariz, Ilona Braspenning-Wesch, Sonja Stephan, Bettina Huber, Gabriele Schmidt, Rui Cao, Martin Müller, Reinhard Kirnbauer, Frank Rösl, Daniel Hasche
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Licensed L1-VLP-based immunizations against high-risk mucosal human papillomavirus (HPV) types have been a great success in reducing anogenital cancers, although they are limited in their cross-protection against HPV types not covered by the vaccine.
Externí odkaz:
https://doaj.org/article/44029ba109ca4877b30f988ba8430789
Differentiation‐related epigenomic changes define clinically distinct keratinocyte cancer subclasses
Autor:
Llorenç Solé‐Boldo, Günter Raddatz, Julian Gutekunst, Oliver Gilliam, Felix Bormann, Michelle S Liberio, Daniel Hasche, Wiebke Antonopoulos, Jan‐Philipp Mallm, Anke S Lonsdorf, Manuel Rodríguez‐Paredes, Frank Lyko
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 9, Pp n/a-n/a (2022)
Abstract Keratinocyte cancers (KC) are the most prevalent malignancies in fair‐skinned populations, posing a significant medical and economic burden to health systems. KC originate in the epidermis and mainly comprise basal cell carcinoma (BCC) and
Externí odkaz:
https://doaj.org/article/f1877efb7d4b4f92a9c149e53c79c250
Autor:
Daniel Hasche, Melinda Ahmels, Ilona Braspenning-Wesch, Sonja Stephan, Rui Cao, Gabriele Schmidt, Martin Müller, Frank Rösl
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Notably, the majority of papillomaviruses associated with a high cancer risk have the potential to translate different isoforms of the L1 major capsid protein. In an infection model, the cutaneous Mastomys natalensis papillomavirus (MnPV) circumvents
Externí odkaz:
https://doaj.org/article/d6ae40e9f63646889d2f2c91aa43b990
Autor:
Yingying Fu, Rui Cao, Miriam Schäfer, Sonja Stephan, Ilona Braspenning-Wesch, Laura Schmitt, Ralf Bischoff, Martin Müller, Kai Schäfer, Sabrina E Vinzón, Frank Rösl, Daniel Hasche
Publikováno v:
eLife, Vol 9 (2020)
Although many high-risk mucosal and cutaneous human papillomaviruses (HPVs) theoretically have the potential to synthesize L1 isoforms differing in length, previous seroepidemiological studies only focused on the short L1 variants, co-assembling with
Externí odkaz:
https://doaj.org/article/d8b9e86c43164c898431dd97d6ecd671
Publikováno v:
Microorganisms, Vol 8, Iss 10, p 1599 (2020)
In times of spreading multidrug-resistant bacteria, species identification and decontamination of cell cultures can be challenging. Here, we describe a mobile cell culture contaminant with “black dot”-like microscopic appearance in newly establis
Externí odkaz:
https://doaj.org/article/b77229dbc1eb46bc8645d32394301ad7
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
There is still controversy in the scientific field about whether certain types of cutaneous human papillomaviruses (HPVs) are causally involved in the development of non-melanoma skin cancer (NMSC). Deciphering the etiological role of cutaneous HPVs
Externí odkaz:
https://doaj.org/article/ac6ed3b552b74db7916b01eaff8790f4
Autor:
Daniel Hasche, Sonja Stephan, Ilona Braspenning-Wesch, Julita Mikulec, Martina Niebler, Hermann-Josef Gröne, Christa Flechtenmacher, Baki Akgül, Frank Rösl, Sabrina E Vinzón
Publikováno v:
PLoS Pathogens, Vol 13, Iss 11, p e1006723 (2017)
Cutaneous human papillomaviruses (HPVs) are considered as cofactors for non-melanoma skin cancer (NMSC) development, especially in association with UVB. Extensively studied transgenic mouse models failed to mimic all aspects of virus-host interaction
Externí odkaz:
https://doaj.org/article/b985d2f4c236433e9d16eca2cd72d93b
Autor:
Daniel Hasche, Frank Rösl
Publikováno v:
Viruses, Vol 11, Iss 2, p 182 (2019)
Replacements of animal models by advanced in vitro systems in biomedical research, despite exceptions, are currently still not satisfactory in reproducing the whole complexity of pathophysiological mechanisms that finally lead to disease. Therefore,
Externí odkaz:
https://doaj.org/article/0295906933674f46a63b93355fe21625
Autor:
Daniel Hasche, Sonja Stephan, Larissa Savelyeva, Frank Westermann, Frank Rösl, Sabrina E Vinzón
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161283 (2016)
In the present report we describe the establishment of a spontaneous immortalized skin keratinocyte cell line derived from the skin of the multimammate rodent Mastomys coucha. These animals are used in preclinical studies for a variety of human disea
Externí odkaz:
https://doaj.org/article/9baed6adca124fd5b770dea769321eee
Publikováno v:
Der Hautarzt. 73:417-425