Zobrazeno 1 - 10 of 58 pro vyhledávání: '"Daniel Hartman"'
1
Akademický článek
The Impact of Immune Checkpoint Inhibitor-Related Adverse Events and Their Immunosuppressive Treatment on Patients’ Outcomes
Autor: Hamzah Abu-Sbeih, Tenglong Tang, Faisal Shaukat Ali, Daniel Hartman Johnson, Wei Qiao, Adi Diab, Yinghong Wang
Publikováno v: Journal of Immunotherapy and Precision Oncology, Pp 7-18 (2018)
Background: Immune checkpoint inhibitors (ICPIs) are gaining more popularity as a treatment for advanced cancers. However, immune-related adverse events (irAEs) limit their use. We aimed to assess the impact of irAEs and their treatment on clinical a
Externí odkaz: https://doaj.org/article/f7d076deb26e4f7685b1a62e5109d7cc
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2
Akademický článek
Effects of CRP infusion on endothelial function and coagulation in normocholesterolemic and hypercholesterolemic subjects
Autor: Radjesh J. Bisoendial, John J.P. Kastelein, Stephan L.M. Peters, Johannes H.M. Levels, Rakesh Birjmohun, Joris I. Rotmans, Daniel Hartman, Joost C.M. Meijers, Marcel Levi, Erik S.G. Stroes
Publikováno v: Journal of Lipid Research, Vol 48, Iss 4, Pp 952-960 (2007)
C-reactive protein (CRP) has been suggested to exert direct adverse effects on the vasculature in experimental setups, including endothelial dysfunction and proinflammatory changes. Here, we assessed the consequences of 1.25 mg/kg highly purified rec
Externí odkaz: https://doaj.org/article/ed37823683e3476eb59e1c27d2a03cb2
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4
Akademický článek
Tissue-colonizing disseminated tumor cells secrete prostaglandin E2 to promote NK cell dysfunction and evade anti-metastatic immunity
Autor: Anna-Marie Pedde, Hyunu Kim, Sainitin Donakonda, Tobias Baumann, Felix Bayerl, Philippa Meiser, Anna Hirschberger, Christine Klement, Simon Grassmann, Rupert Öllinger, Norbert Hüser, Daniel Hartmann, Melanie Laschinger, Joseph A. Trapani, Alfred Zippelius, Tobias Bald, Gabriela M. Wiedemann, Roland Rad, Joseph C. Sun, Bastian Höchst, Jan P. Böttcher
Publikováno v: Cell Reports, Vol 43, Iss 11, Pp 114855- (2024)
Summary: Natural killer (NK) cells are critical for anti-metastatic immunity and can eliminate metastasizing tumor cells within circulation and sites of metastatic seeding. Here, we show that disseminated tumor cells (DTCs) colonizing the mouse lung
Externí odkaz: https://doaj.org/article/f59733942ee14e7693060de6e6edd91a
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7
Modeling of sustained spontaneous network oscillations of a sexually dimorphic brainstem nucleus: the role of potassium equilibrium potential
Autor: Iulian Ilieş, Daniel Hartman, Dávid Lehotzky, Günther K.H. Zupanc, Mariana Levi
Publikováno v: Journal of computational neuroscience. 49(4)
Intrinsic oscillators in the central nervous system play a preeminent role in the neural control of rhythmic behaviors, yet little is known about how the ionic milieu regulates their output patterns. A powerful system to address this question is the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7c2043d857a5b63419a03254942420
https://pubmed.ncbi.nlm.nih.gov/34032982
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8
Use of RWE to Inform Regulatory, Public Health Policy, and Intervention Priorities for the Developing World
Autor: Steven E. Kern, Murray Lumpkin, Douglas S. McNair, Daniel Hartman
Publikováno v: Clinical pharmacology and therapeutics. 111(1)
For low- and middle-income countries (LMICs) to benefit from real-world evidence (RWE)/real-world data (RWD) in both product registration ("regulatory") decision making and in product utilization policy ("policy") decision making, they need to overco
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf33248cbfca7095aa2a43375916cda
https://pubmed.ncbi.nlm.nih.gov/34655224
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