Výsledky vyhledávání - "Daniel Hamaoui"

Akademický článek

Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division

Autor: Serena Petracchini, Daniel Hamaoui, Anne Doye, Atef Asnacios, Florian Fage, Elisa Vitiello, Martial Balland, Sebastien Janel, Frank Lafont, Mukund Gupta, Benoit Ladoux, Jerôme Gilleron, Teresa M. Maia, Francis Impens, Laurent Gagnoux-Palacios, Mads Daugaard, Poul H. Sorensen, Emmanuel Lemichez, Amel Mettouchi

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)

Uropathogenic strains of Escherichia coli (UPEC) are a leading cause of urinary tract infections (UTIs) and invasion involves Rho GTPase members, notably Rac1, to drive actin cytoskeleton rearrangement leading to engulfment. Here, Petracchini et al.

Externí odkaz: https://doaj.org/article/1958110237ff42f391f49c167f39e785

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Akademický článek

Ezrin enhances line tension along transcellular tunnel edges via NMIIa driven actomyosin cable formation

Autor: Caroline Stefani, David Gonzalez-Rodriguez, Yosuke Senju, Anne Doye, Nadia Efimova, Sébastien Janel, Justine Lipuma, Meng Chen Tsai, Daniel Hamaoui, Madhavi P. Maddugoda, Olivier Cochet-Escartin, Coline Prévost, Frank Lafont, Tatyana Svitkina, Pekka Lappalainen, Patricia Bassereau, Emmanuel Lemichez

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)

Holes in endothelial barriers, called transendothelial cell macroapertures (TEMs), are predicted to be limited by line tension of unknown origin. Here the authors identify an actomyosin cable encircling TEMs and establish a role for ezrin in stabilis

Externí odkaz: https://doaj.org/article/b124a0879bef45a0aa24bea545ed4ff2

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Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division

Autor: Laurent Gagnoux, Serena Petracchini, Benoit Ladoux, Amel Mettouchi, Martial Balland, Mads Daugaard, Mukund Gupta, Emmanuel Lemichez, Francis Impens, Poul H. Sorensen, Sébastien Janel, Elisa Vitiello, Anne Doye, Frank Lafont, Florian Fage, Atef Asnacios, Teresa Mendes Maia, Daniel Hamaoui, Jerome Gilleron

Publikováno v: Nature Communications
Nature Communications, 2022, 13 (1), pp.6059. ⟨10.1038/s41467-022-33803-x⟩
NATURE COMMUNICATIONS

Extracellular matrix (ECM) elasticity is perceived by cells via focal adhesion structures, which transduce mechanical cues into chemical signalling to conform cell behavior. Although the contribution of ECM compliance to the control of cell migration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63bf79f8817df4bfc8680ab0c70a1059

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PI4P and BLOC-1 remodel endosomal membranes into tubules

Autor: Daniel Lévy, Feng-Ching Tsai, Daniel Hamaoui, Sílvia Vale-Costa, Maria João Amorim, Aurélie Di Cicco, Yueyao Zhu, Anne-Sophie Macé, Tal Keren-Kaplan, Mathilde Dimarco, Cédric Delevoye, Patricia Bassereau, Ilse Hurbain, Juan S. Bonifacino, Michael S. Marks, Agathe Subtil, Riddhi Atul Jani, Graça Raposo

Publikováno v: Journal of Cell Biology
Journal of Cell Biology, 2022, 221 (11), pp.e202110132. ⟨10.1083/jcb.202110132⟩

International audience; The endosomal sorting complexes required for transport (ESCRT) system is an ancient and ubiquitous membrane scission machinery that catalyzes the budding and scission of membranes. ESCRT-mediated scission events, exemplified b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233669a4d26091add9612c1976ec4280
https://hal.archives-ouvertes.fr/hal-03452929

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ATG16L1 functions in cell homeostasis beyond autophagy

Autor: Agathe Subtil, Daniel Hamaoui

Publikováno v: FEBS Journal
FEBS Journal, Wiley, 2021, ⟨10.1111/febs.15833⟩
FEBS Journal, 2021, ⟨10.1111/febs.15833⟩

International audience; Atg16-like (ATG16L) proteins were identified in higher eukaryotes for their resemblance to Atg16, a yeast protein previously characterized as a subunit of the Atg12-Atg5/Atg16 complex. In yeast, this complex catalyzes the lipi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f4c161c80d57772cfe87e868048874
https://hal-pasteur.archives-ouvertes.fr/pasteur-03413222/file/HAL_version.pdf

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Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation

Autor: Emilie Andrio, Emmanuel Lemichez, Jacqueline Cherfils, Poul H. Sorensen, Anne Doye, Daniel Hamaoui, Mads Daugaard, Raymond Ruimy, Frédéric Bost, Amel Mettouchi, Romain Lotte

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.44779. ⟨10.1038/srep44779⟩
Scientific Reports, 2017, 7 (1), pp.44779. ⟨10.1038/srep44779⟩

The E3 ubiquitin ligase HACE1 is a potent tumor suppressor that controls cell proliferation and ubiquitylates the small GTPase Rac1 to target it to proteasomal degradation. Whether and how the activity of HACE1 is regulated by the N-terminal ankyrin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369d0aeadf452cafe8e400b065e715d7
https://doi.org/10.1038/srep44779

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Screening in Planarians Identifies MORN2 as a Key Component in LC3-Associated Phagocytosis and Resistance to Bacterial Infection

Publikováno v: Cell Host and Microbe
Cell Host and Microbe, 2014, 16 (3), pp.338-350. ⟨10.1016/j.chom.2014.08.002⟩
Cell Host and Microbe, Elsevier, 2014, 16 (3), pp.338-350. ⟨10.1016/j.chom.2014.08.002⟩

International audience; Dugesia japonica planarian flatworms are naturally exposed to various microbes but typically survive this challenge. We show that planarians eliminate bacteria pathogenic to Homo sapiens, Caenorhabditis elegans, and/or Drosoph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062e3641aa46d030d99bf97281eecc3f
https://hal.science/hal-02111891

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