Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Daniel H. LaChance"'
Autor:
Evanthia Galanis, Katharine E. Dooley, S. Keith Anderson, Cheyne B. Kurokawa, Xiomara W. Carrero, Joon H. Uhm, Mark J. Federspiel, Alexey A. Leontovich, Ileana Aderca, Kimberly B. Viker, Julie E. Hammack, Randolph S. Marks, Steven I. Robinson, Derek R. Johnson, Timothy J. Kaufmann, Jan C. Buckner, Daniel H. Lachance, Terry C. Burns, Caterina Giannini, Aditya Raghunathan, Ianko D. Iankov, Ian F. Parney
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Measles virus (MV) vaccine strains have shown significant preclinical antitumor activity against glioblastoma (GBM), the most lethal glioma histology. In this first in human trial (NCT00390299), a carcinoembryonic antigen-expressing oncolyti
Externí odkaz:
https://doaj.org/article/436353bf6b554a7ca56ec210185c93df
Autor:
Quinn T. Ostrom, Ben Kinnersley, Margaret R. Wrensch, Jeanette E. Eckel-Passow, Georgina Armstrong, Terri Rice, Yanwen Chen, John K. Wiencke, Lucie S. McCoy, Helen M. Hansen, Christopher I. Amos, Jonine L. Bernstein, Elizabeth B. Claus, Dora Il’yasova, Christoffer Johansen, Daniel H. Lachance, Rose K. Lai, Ryan T. Merrell, Sara H. Olson, Siegal Sadetzki, Joellen M. Schildkraut, Sanjay Shete, Joshua B. Rubin, Justin D. Lathia, Michael E. Berens, Ulrika Andersson, Preetha Rajaraman, Stephen J. Chanock, Martha S. Linet, Zhaoming Wang, Meredith Yeager, GliomaScan consortium, Richard S. Houlston, Robert B. Jenkins, Beatrice Melin, Melissa L. Bondy, Jill. S. Barnholtz-Sloan
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Incidence of glioma is approximately 50% higher in males. Previous analyses have examined exposures related to sex hormones in women as potential protective factors for these tumors, with inconsistent results. Previous glioma genome-wide ass
Externí odkaz:
https://doaj.org/article/967d38752bd941368f970001b4a08515
Autor:
Connor Yanchus, Kristen L. Drucker, Thomas M. Kollmeyer, Ricky Tsai, Warren Winick-Ng, Minggao Liang, Ahmad Malik, Judy Pawling, Silvana B. De Lorenzo, Asma Ali, Paul A. Decker, Matt L. Kosel, Arijit Panda, Khalid N. Al-Zahrani, Lingyan Jiang, Jared W. L. Browning, Chris Lowden, Michael Geuenich, J. Javier Hernandez, Jessica T. Gosio, Musaddeque Ahmed, Sampath Kumar Loganathan, Jacob Berman, Daniel Trcka, Kulandaimanuvel Antony Michealraj, Jerome Fortin, Brittany Carson, Ethan W. Hollingsworth, Sandra Jacinto, Parisa Mazrooei, Lily Zhou, Andrew Elia, Mathieu Lupien, Housheng Hansen He, Daniel J. Murphy, Liguo Wang, Alexej Abyzov, James W. Dennis, Philipp G. Maass, Kieran Campbell, Michael D. Wilson, Daniel H. Lachance, Margaret Wrensch, John Wiencke, Tak Mak, Len A. Pennacchio, Diane E. Dickel, Axel Visel, Jeffrey Wrana, Michael D. Taylor, Gelareh Zadeh, Peter Dirks, Jeanette E. Eckel-Passow, Liliana Attisano, Ana Pombo, Cristiane M. Ida, Evgeny Z. Kvon, Robert B. Jenkins, Daniel Schramek
Publikováno v:
Science
Establishing causal links between inherited polymorphisms and cancer risk is challenging. Here, we focus on the single-nucleotide polymorphism rs55705857, which confers a sixfold greater risk of isocitrate dehydrogenase ( IDH) –mutant low-grade gli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee0962bd008ed19485d953421b33939b
https://doi.org/10.1126/science.abj2890
https://doi.org/10.1126/science.abj2890
Autor:
Jeanette E Eckel-Passow, Daniel H Lachance, Paul A Decker, Thomas M Kollmeyer, Matthew L Kosel, Kristen L Drucker, Susan Slager, Margaret Wrensch, W Oliver Tobin, Robert B Jenkins
Publikováno v:
Neurooncol Pract
Knowledge about inherited and acquired genetics of adult diffuse glioma has expanded significantly over the past decade. Genomewide association studies (GWAS) stratified by histologic subtype identified six germline variants that were associated spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa35dc7694724917b05df32b1885539
https://doi.org/10.1093/nop/npac017
https://doi.org/10.1093/nop/npac017
Autor:
Margaret R. Wrensch, Robert B. Jenkins, Kathleen M. Egan, John K. Wiencke, James E. Browning, Melissa H. Madden, Steve Brem, Jeffrey J. Olson, Louis Burt Nabors, Reid C. Thompson, Jan C. Buckner, Brian Patrick O'Neill, Daniel H. Lachance, Brooke L. Fridley, Matthew L. Kosel, Mitchel S. Berger, Susan M. Chang, Michael D. Prados, Tarik Tihan, Joe L. Wiemels, Helen M. Hansen, Joseph S. Patoka, Ivan Smirnov, Lucie S. McCoy, Terri Rice, Paul A. Decker, Yuanyuan Xiao
Purpose: Glioblastoma is a devastating, incurable disease with few known prognostic factors. Here, we present the first genome-wide survival and validation study for glioblastoma.Experimental Design: Cox regressions for survival with 314,635 inherite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab65fca7e9f3f83bae3896de687db65
https://doi.org/10.1158/1078-0432.c.6520185.v1
https://doi.org/10.1158/1078-0432.c.6520185.v1
Autor:
Joseph L. Wiemels, Catherine Metayer, Xiaomei Ma, Margaret R. Wrensch, Robert B. Jenkins, John K. Wiencke, Jeanette E. Eckel-Passow, Daniel H. Lachance, Lucie S. McCoy, Cecilia H. Fu, Terri Rice, Jianqiao Xiao, Alyson A. Endicott, Semira Gonseth, Ivan V. Smirnov, Helen M. Hansen, Adam J. de Smith, Kyle M. Walsh
Subject characteristics of cases and controls undergoing genetic association analyses from the California Childhood Leukemia Study, The Children's Oncology Group, The Wellcome Trust Consortium, the GENEVA Melanoma Study, The University of California,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab483bb14f52ee590567886bfa40b3c
https://doi.org/10.1158/0008-5472.22410779.v1
https://doi.org/10.1158/0008-5472.22410779.v1
Autor:
Joseph L. Wiemels, Catherine Metayer, Xiaomei Ma, Margaret R. Wrensch, Robert B. Jenkins, John K. Wiencke, Jeanette E. Eckel-Passow, Daniel H. Lachance, Lucie S. McCoy, Cecilia H. Fu, Terri Rice, Jianqiao Xiao, Alyson A. Endicott, Semira Gonseth, Ivan V. Smirnov, Helen M. Hansen, Adam J. de Smith, Kyle M. Walsh
Genome-wide association studies (GWAS) have identified SNPs in six genes that are associated with childhood acute lymphoblastic leukemia (ALL). A lead SNP was found to occur on chromosome 9p21.3, a region that is deleted in 30% of childhood ALLs, sug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044d859117d7d1a6a5e73e258aab2d8e
https://doi.org/10.1158/0008-5472.c.6508067.v1
https://doi.org/10.1158/0008-5472.c.6508067.v1
Autor:
Jann N. Sarkaria, Ian F. Parney, Robert B. Jenkins, Caterina Giannini, Nhan L. Tran, Brian P. O'Neill, Fredrick B. Meyer, Terry C. Burns, Erik P. Sulman, Roel G. Verhaak, Jeanette E. Eckel-Passow, Daniel H. LaChance, Andrea Califano, Eric W. Klee, Bianca M. Marin, Qianghu Wang, Michael E. Berens, Harshil D. Dhruv, Huihuang Yan, Paul A. Decker, Lisa Evers, Gobinda Sarkar, Daniel J. Ma, Brett L. Carlson, Sen Peng, Rebecca Grove, Thomas M. Kollmeyer, Alissa Caron, Gaspar J. Kitange, Ann C. Mladek, Mark A. Schroeder, Dioval Remonde, Shulan Tian, Rachael A. Vaubel
Genetics of recurrent PDX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a9c1b2dc946e2a7e9fe8b874f98133
https://doi.org/10.1158/1078-0432.22473342
https://doi.org/10.1158/1078-0432.22473342
Autor:
Sean J. Pittock, Christopher Klein, Andrew McKeon, Carin Y. Smith, Sarah M. Jenkins, Daniel H. Lachance, Vanda A. Lennon, Erika S. Horta
PDF file - 118KB, Supplementary Table 1. number of patients for each observed clusters with 4 autoantibodies. Supplementary Table 2. Number of patients for each observed clusters with 5 autoantibodies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205e3f3922bf71a8757e6b042f59d1a3
https://doi.org/10.1158/1078-0432.22455546
https://doi.org/10.1158/1078-0432.22455546
Autor:
Jann N. Sarkaria, Ian F. Parney, Robert B. Jenkins, Caterina Giannini, Nhan L. Tran, Brian P. O'Neill, Fredrick B. Meyer, Terry C. Burns, Erik P. Sulman, Roel G. Verhaak, Jeanette E. Eckel-Passow, Daniel H. LaChance, Andrea Califano, Eric W. Klee, Bianca M. Marin, Qianghu Wang, Michael E. Berens, Harshil D. Dhruv, Huihuang Yan, Paul A. Decker, Lisa Evers, Gobinda Sarkar, Daniel J. Ma, Brett L. Carlson, Sen Peng, Rebecca Grove, Thomas M. Kollmeyer, Alissa Caron, Gaspar J. Kitange, Ann C. Mladek, Mark A. Schroeder, Dioval Remonde, Shulan Tian, Rachael A. Vaubel
Purpose:Glioblastoma is the most frequent and lethal primary brain tumor. Development of novel therapies relies on the availability of relevant preclinical models. We have established a panel of 96 glioblastoma patient-derived xenografts (PDX) and un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b691d7bcb07b6838eddd724e76350d
https://doi.org/10.1158/1078-0432.c.6528489
https://doi.org/10.1158/1078-0432.c.6528489