Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Daniel H. Ebert"'
Autor:
David A. Harmin, Daniel H. Ebert, Hume Stroud, Martin Hemberg, Benyam Kinde, Nathaniel R. Kastan, Caitlin S. Gilbert, Michael E. Greenberg, Harrison W. Gabel
Publikováno v:
Nature. 522:89-93
Rett syndrome is caused by mutation of the MECP2 gene that codes for a protein that binds methylated DNA; this study reveals that MeCP2 affects the expression of long genes, which often serve neuronal functions. Autism-related Rett syndrome is caused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cff3b8ce82f84db3a0c752c7a636f643
https://doi.org/10.1038/nature14319
https://doi.org/10.1038/nature14319
Autor:
Robert Ekiert, Nathaniel D. Robinson, Daniel H. Ebert, Jim Selfridge, Nathaniel R. Kastan, Cara Merusi, Michael E. Greenberg, Juri Rappsilber, Jacky Guy, Jakub Stanislaw Nowak, Flavia de Lima Alves, Matthew J. Lyst, Adrian Bird
Publikováno v:
Nature Neuroscience. 16:898-902
Rett syndrome (RTT) is a severe neurological disorder that is caused by mutations in the MECP2 gene. Many missense mutations causing RTT are clustered in the DNA-binding domain of MeCP2, suggesting that association with chromatin is critical for its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d252be7ad5c3b8018ec4230015b2d791
https://doi.org/10.1038/nn.3434
https://doi.org/10.1038/nn.3434
Autor:
Michael E. Greenberg, Daniel H. Ebert
Publikováno v:
Nature. 493:327-337
Neuronal activity induces the post-translational modification of synaptic molecules, promotes localized protein synthesis within dendrites and activates gene transcription, thereby regulating synaptic function and allowing neuronal circuits to respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18134c8bbaa014b7da41c8d0d96e3a42
https://doi.org/10.1038/nature11860
https://doi.org/10.1038/nature11860
Autor:
Miyuki Suzawa, Daniel H. Ebert, Holly A. Ingraham, Emily J. Faivre, Florence Y. Lee, Denise D. Belsham, Erik Lontok, Fang Cai
Publikováno v:
Developmental Cell. 21:315-327
SummarySumoylation is generally considered a repressive mark for many transcription factors. However, the in vivo importance of sumoylation for any given substrate remains unclear and is questionable because the extent of sumoylation appears exceedin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8d4975961ce9ee47615c42cd45df83
https://doi.org/10.1016/j.devcel.2011.06.028
https://doi.org/10.1016/j.devcel.2011.06.028
Autor:
Adele M. Lehane, Anupam Pradhan, David A. Fidock, Dennis E. Kyle, Gloria Holbrook, Amy Matheny, Martina Sigal, Anang A. Shelat, David Waterson, Iñigo Angulo-Barturen, Kathleen O’Loughlin, Jian Liu, Laura M. Sanz, Philip D. Stein, Daniel H. Ebert, Kiaran Kirk, Hongshen Ma, Marcus C. S. Lee, Jon C. Mirsalis, W. Armand Guiguemde, Xiaoyan Deng, Greg Fedewa, Ane Rodríguez-Alejandre, María Belén Jiménez-Díaz, María G. Gómez, Angela K. Carrillo, Mariana Justino de Almeida, Yandira G. Salinas, Vicky M. Avery, David M. Shackleford, Sandra Duffy, Marie-Eve Myrand-Lapierre, Gregory M. Miller, María Santos Martínez, Adelaide S. M. Dennis, Charles C. Kim, R. Kiplin Guy, Julie Clark, Jeremy A. Horst, Aaron N. Endsley, Joseph L. DeRisi, Zheng Wang, Spencer Knapp, Fangyi Zhu, David M. Floyd, Santiago Ferrer, Jonathon Diep, Francisco-Javier Gamo, Susan A. Charman, Natalie J. Spillman
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 111, iss 50
Drug discovery for malaria has been transformed in the last 5 years by the discovery of many new lead compounds identified by phenotypic screening. The process of developing these compounds as drug leads and studying the cellular responses they induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd38753b4b27787a1d271647ca26a4f8
https://europepmc.org/articles/PMC4273362/
https://europepmc.org/articles/PMC4273362/
Publikováno v:
Journal of Biological Chemistry. 279:3837-3851
Persistent reovirus infections of murine L929 (L) fibroblast cells select mutant (LX) cells that do not support proteolytic disassembly of reovirus virions within the endocytic pathway. To better understand the function and regulation of endocytic pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b439336c2dd3c687fa5870647242ba
https://doi.org/10.1074/jbc.m310048200
https://doi.org/10.1074/jbc.m310048200
Publikováno v:
Journal of Biological Chemistry. 277:24609-24617
After attachment to receptors, reovirus virions are internalized by endocytosis and exposed to acid-dependent proteases that catalyze viral disassembly. Previous studies using the cysteine protease inhibitor E64 and a mutant cell line that does not s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4b902d881dc9659f033c02dcd9889a
https://doi.org/10.1074/jbc.m201107200
https://doi.org/10.1074/jbc.m201107200
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178163 (2017)
PloS one, vol 12, iss 5
PLoS ONE
PloS one, vol 12, iss 5
PLoS ONE
Genetic manipulation of the deadly malaria parasite Plasmodium falciparum remains challenging, but the rise of CRISPR/Cas9-based genome editing tools is increasing the feasibility of altering this parasite’s genome in order to study its biology. Of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b478bebccc4265764063c37a5f52a88
https://doi.org/10.1371/journal.pone.0178163
https://doi.org/10.1371/journal.pone.0178163
Autor:
Geoffrey S. Baer, D. E. Brumbaugh, Daniel H. Ebert, Terence S. Dermody, S. R. Chance, J D Wetzel, L. E. Stobie
Publikováno v:
Journal of Virology. 75:3197-3206
Reovirus virions are internalized into cells by receptor-mediated endocytosis. Within the endocytic compartment, the viral outer capsid undergoes acid-dependent proteolysis leading to degradation of ς3 protein and proteolytic cleavage of μ1/μ1C pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32111e1c6dc90307fc2dd20743252685
https://doi.org/10.1128/jvi.75.7.3197-3206.2001
https://doi.org/10.1128/jvi.75.7.3197-3206.2001
Autor:
Annah N. Abrams, Menekse Alpay, Jonathan E. Alpert, B.J. Beck, Anne E. Becker, Eugene V. Beresin, Mark A. Blais, Ilana M. Braun, Rebecca W. Brendel, Megan Moore Brennan, George Bush, Jason P. Caplan, Paolo Cassano, Ned H. Cassem, T. Atilla Ceranoglu, Lee S. Cohen, M. Cornelia Cremens, Cristina Cusin, Abigail L. Donovan, Daniel H. Ebert, Lucy A. Epstein, William E. Falk, Maurizio Fava, Carlos Fernandez-Robles, Christine T. Finn, Marlene P. Freeman, Oliver Freudenreich, Gregory L. Fricchione, David R. Gastfriend, Donald C. Goff, Christopher Gordon, Donna B. Greenberg, Anne F. Gross, James E. Groves, Thomas P. Hackett, Stephan Heckers, David C. Henderson, Jeff C. Huffman, Dan V. Iosifescu, Esther Jacobowitz Israel, James L. Januzzi, Michael S. Jellinek, Nicholas Kontos, Karsten Kueppenbender, Brian P. Kurtz, Isabel T. Lagomasino, Boris A. Lorberg, Bruce J. Masek, Guy Maytal, Edward Messner, David Mischoulon, Anna C. Muriel, George B. Murray, Shamim H. Nejad, Dana Diem Nguyen, Ruta Nonacs, Dennis K. Norman, Sheila M. O'Keefe, Michael W. Otto, Brian A. Palmer, George I. Papakostas, Jennifer M. Park, Lawrence Park, Roy H. Perlis, Margot Phillips, William F. Pirl, Mark H. Pollack, Laura M. Prager, Jefferson B. Prince, John Querques, Davin K. Quinn, Terry Rabinowitz, Paula K. Rauch, Scott L. Rauch, John A. Renner, Joshua L. Roffman, Jerrold F. Rosenbaum, Julie D. Ross, Kristin S. Russell, Kathy M. Sanders, Lisa Scharff, Steven C. Schlozman, Ronald Schouten, Linda C. Shafer, Benjamin C. Silverman, Patrick Smallwood, Felicia A. Smith, Jordan W. Smoller, Robert M. Stern, Theodore A. Stern, Jonathan R. Stevens, Thomas D. Stewart, Frederick J. Stoddard, Joan M. Stoler, Paul Summergrad, Owen S. Surman, Jennifer J. Thomas, Adrienne O. van Nieuwenhuizen, Adele C. Viguera, Betty Wang, Marlynn Wei, Avery D. Weisman, Anthony P. Weiss, Charles A. Welch, Ilse R. Wiechers, Marketa M. Wills, Curtis W. Wittmann, Jonathan L. Worth, Daniel J. Zimmerman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bc0e799e1eb215dcbbc316211548f50
https://doi.org/10.1016/b978-1-4377-1927-7.00058-3
https://doi.org/10.1016/b978-1-4377-1927-7.00058-3