Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Daniel H Kaplan"'
Autor:
Jacinto S. De La Cruz Diaz, Toshiro Hirai, Breanna Anh-Thu Nguyen, Yukari Zenke, Yi Yang, Haiyue Li, Stephen Nishimura, Daniel H. Kaplan
Publikováno v:
JID Innovations, Vol 1, Iss 3, Pp 100028- (2021)
In the skin, Langerhans cells (LCs) require autocrine latent TGFβ that is transactivated by the integrins ανβ6 and ανβ8 expressed by keratinocytes (KCs) for long-term epidermal retention. Selective expression of a ligand-independent, constitut
Externí odkaz:
https://doaj.org/article/94b7a78725d74d748521e29889f42f04
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:1169-1177
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a0f567b2ed427d015c770136eb83d60
https://doi.org/10.1016/j.jaci.2023.03.013
https://doi.org/10.1016/j.jaci.2023.03.013
Autor:
Emilie V Russler-Germain, Jaeu Yi, Shannon Young, Katherine Nutsch, Harikesh S Wong, Teresa L Ai, Jiani N Chai, Vivek Durai, Daniel H Kaplan, Ronald N Germain, Kenneth M Murphy, Chyi-Song Hsieh
Publikováno v:
eLife, Vol 10 (2021)
Generation of tolerogenic peripheral regulatory T (pTreg) cells is commonly thought to involve CD103+ gut dendritic cells (DCs), yet their role in commensal-reactive pTreg development is unclear. Using two Helicobacter-specific T cell receptor (TCR)
Externí odkaz:
https://doaj.org/article/007c449ec2de46e180b76c8533b9af29
Autor:
Yale Liu, Christopher Cook, Andrew J. Sedgewick, Shuyi Zhang, Marlys S. Fassett, Roberto R. Ricardo-Gonzalez, Paymann Harirchian, Sakeen W. Kashem, Sho Hanakawa, Jacob R. Leistico, Jeffrey P. North, Mark A. Taylor, Wei Zhang, Mao-Qiang Man, Alexandra Charruyer, Nadejda Beliakova-Bethell, Stephen C. Benz, Ruby Ghadially, Theodora M. Mauro, Daniel H. Kaplan, Kenji Kabashima, Jaehyuk Choi, Jun S. Song, Raymond J. Cho, Jeffrey B. Cheng
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101582- (2020)
Summary: Inflammatory response heterogeneity has impeded high-resolution dissection of diverse immune cell populations during activation. We characterize mouse cutaneous immune cells by single-cell RNA sequencing, after inducing inflammation using im
Externí odkaz:
https://doaj.org/article/642c47211ea24e3c8cf04b0ca1279bd0
Autor:
Daniela Y. Kitashima, Tetsuro Kobayashi, Therese Woodring, Kacey Idouchi, Thomas Doebel, Benjamin Voisin, Takeya Adachi, Takeshi Ouchi, Hayato Takahashi, Koji Nishifuji, Daniel H. Kaplan, Björn E. Clausen, Masayuki Amagai, Keisuke Nagao
Publikováno v:
EBioMedicine, Vol 27, Iss C, Pp 293-303 (2018)
Langerhans cells (LCs) are antigen-presenting cells in the epidermis whose roles in antigen-specific immune regulation remain incompletely understood. Desmoglein 3 (Dsg3) is a keratinocyte cell-cell adhesion molecule critical for epidermal integrity
Externí odkaz:
https://doaj.org/article/2802e92f0c0045a1aa5bda73e6c6dbf9
Autor:
Rob van Dalen, Jacinto S. De La Cruz Diaz, Matevž Rumpret, Felix F. Fuchsberger, Nienke H. van Teijlingen, Jonas Hanske, Christoph Rademacher, Teunis B. H. Geijtenbeek, Jos A. G. van Strijp, Christopher Weidenmaier, Andreas Peschel, Daniel H. Kaplan, Nina M. van Sorge
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Staphylococcus aureus is a major cause of skin and soft tissue infections and aggravator of the inflammatory skin disease atopic dermatitis (AD [eczema]). Epicutaneous exposure to S. aureus induces Th17 responses through skin Langerhans cell
Externí odkaz:
https://doaj.org/article/5381197dcad241c8928ae7c4eb2becaf
Autor:
David S Nelson, Ryan L Marano, Yechaan Joo, Sara Y Tian, Bhumi Patel, Daniel H Kaplan, Mark J Shlomchik, Kristen Stevenson, Roderick T Bronson, Barrett J Rollins
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222400 (2019)
Langerhans cell histiocytosis (LCH) is characterized by the accumulation of Langerin (CD207)-expressing histiocytes. Mutational activation of mitogen-activated protein kinase pathway genes, in particular BRAF, drives most cases. To test whether activ
Externí odkaz:
https://doaj.org/article/558463d275d0429ebb07e2d707219cea
Publikováno v:
Journal of Investigative Dermatology. 142:841-848
Skin-resident mast cells (MCs) and cutaneous sensory neurons both play crucial roles in microbial‒host defense and inflammatory diseases. MCs can be directly activated by pathogens or their products, resulting in the release of numerous mediators t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78aca1bc322895111358b5288a8218c5
https://doi.org/10.1016/j.jid.2021.10.006
https://doi.org/10.1016/j.jid.2021.10.006
Autor:
Sarah K. Whitley, Mushi Li, Sakeen W. Kashem, Toshiro Hirai, Botond Z. Igyártó, Kelley Knizner, Jonhan Ho, Laura K. Ferris, Casey T. Weaver, Daniel J. Cua, Mandy J. McGeachy, Daniel H. Kaplan
Publikováno v:
Science Immunology. 7
The cytokine interleukin-23 (IL-23) is critical for development and maintenance of autoimmune inflammation in nonlymphoid tissues; however, the mechanism through which IL-23 supports tissue-specific immunity remains unclear. In mice, we found that ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75e2d3b84999d416b9f74700a391e0bd
https://doi.org/10.1126/sciimmunol.abq3254
https://doi.org/10.1126/sciimmunol.abq3254
Autor:
Jonathan A. Cohen, Daniel H. Kaplan
Publikováno v:
Immunity. 55:11-13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93d9863ab8658e642a3e66a531a005b4
https://doi.org/10.1016/j.immuni.2021.12.011
https://doi.org/10.1016/j.immuni.2021.12.011