Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Daniel H Fine"'
Autor:
Janine Fredericks-Younger, Daniel H Fine, Gayathri Subramanian, Modupe O Coker, Cyril Meyerowitz, Patricia Ragusa, Veerasathpurush Allareddy, Mary Ann McBurnie, Ellen Funkhouser, Maria Laura Gennaro, Cecile A Feldman
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 8, p e38386 (2022)
BackgroundDental practice has been greatly affected by the COVID-19 pandemic. As SARS-CoV-2 infection is transmitted by respiratory fluids, dental practice techniques, which include aerosol-generating procedures, can increase the risk of transmission
Externí odkaz:
https://doaj.org/article/06054111dda5432586ff9756394e470d
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151361 (2016)
Leukotoxin (Ltx) is a prominent virulence factor produced by Aggregatibacter actinomycetemcomitans, an oral microorganism highly associated with aggressive periodontitis. Ltx compromises host responsiveness by altering the viability of neutrophils, l
Externí odkaz:
https://doaj.org/article/31cdc75c24d24f2dbd7d12e9245d3eb2
Autor:
Niki M Moutsopoulos, Natalia I Chalmers, Jennifer J Barb, Loreto Abusleme, Teresa Greenwell-Wild, Nicolas Dutzan, Bruce J Paster, Peter J Munson, Daniel H Fine, Gulbu Uzel, Steven M Holland
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004698 (2015)
Leukocyte Adhesion Deficiency I (LAD-I) is a primary immunodeficiency caused by single gene mutations in the CD18 subunit of β2 integrins which result in defective transmigration of neutrophils into the tissues. Affected patients suffer from recurre
Externí odkaz:
https://doaj.org/article/addaa8ab8c734d1885454a19dd2a2995
Autor:
Mayilvahanan Shanmugam, Prerna Gopal, Faiha El Abbar, Helen C Schreiner, Jeffrey B Kaplan, Daniel H Fine, Narayanan Ramasubbu
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117487 (2015)
Aggregatibacter actinomycetemcomitans a causative agent of periodontal disease in humans, forms biofilm on biotic and abiotic surfaces. A. actinomycetemcomitans biofilm is heterogeneous in nature and is composed of proteins, extracellular DNA and exo
Externí odkaz:
https://doaj.org/article/68c18fdea0c847e786f5b37d56ad6a1f
Autor:
Daniel H Fine, Kenneth Markowitz, Karen Fairlie, Debbie Tischio-Bereski, Javier Ferrandiz, Dipti Godboley, David Furgang, John Gunsolley, Al Best
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98541 (2014)
Improved diagnostics remains a fundamental goal of biomedical research. This study was designed to assess cytokine biomarkers that could predict bone loss (BL) in localized aggressive periodontitis. 2,058 adolescents were screened. Two groups of 50 p
Externí odkaz:
https://doaj.org/article/394a3d74c03a44ac9a3d7f8f445f9d09
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69382 (2013)
Our aim was to explore the effects of Cytolethal Distending toxin (Cdt) in a well established rat model of periodontal disease where leukotoxin (LtxA) was thought to have no known effect. In vitro studies, were used to assess CdtB activity using Aa L
Externí odkaz:
https://doaj.org/article/bbdd56f39b4e420abd448f4e17940e61
Autor:
Sera Jacob, Luciana Gusmao, Dipti Godboley, Senthil Kumar Velusamy, Nisha George, Helen Schreiner, Carla Cugini, Daniel H. Fine
Publikováno v:
Pathogens, Vol 13, Iss 11, p 1011 (2024)
Aggregatibacter actinomycetemcomitans ApiA is a trimeric autotransporter outer membrane protein (Omp) that participates in multiple functions, enabling A. actinomycetemcomitans to adapt to a variety of environments. The goal of this study is to ident
Externí odkaz:
https://doaj.org/article/8618079133694c12a36faa8720f7e932
Autor:
Cecile A. Feldman, Janine Fredericks-Younger, Daniel H. Fine, Kenneth Markowitz, Emily Sabato
Publikováno v:
The Journal of the American Dental Association.
Autor:
Cecile A. Feldman, Janine Fredericks-Younger, Gayathri Subramanian, Maria Laura Gennaro, Modupe O. Coker, Daniel H. Fine
Publikováno v:
Journal of the American Dental Association (1939)
Autor:
Satoko Matsumura, Emi Shimizu, Amel Dudakovic, Andre J. van Wijnen, Marwa Choudhury, Daniel H. Fine, Siva P.V. Nadimpalli, Yoshifumi Kobayashi, Henry F. Duncan, Richard Johnson, Angela Quispe-Salcedo, Sanika Bodas, Erhao Li
Publikováno v:
Biochem Biophys Res Commun
Enhancer of zeste homolog 2 (EZH2) is the catalytic core of polycomb repressive complex 2 (PRC2), which primarily methylates lysine 27 on histone H3 (H2K27me3), generating transcriptionally suppressed heterochromatin. Since EZH2 suppresses expression