Uptake of aminoglycosides through outer membrane porins in Escherichia coli

Autor: Eshita Paul, Ishan Ghai, Daniel Hörömpöli, Heike Brötz-Oesterhelt, Mathias Winterhalter, Jayesh A Bafna

Aminoglycosides are important clinical antibiotics but their molecular uptake mechanism is still not completely understood. Here we quantify and compare the passive transport of three aminoglycosides (kanamycin, gentamicin, and amikacin) across gener

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31696b416f5068455e2d326cba6ed9dc
https://doi.org/10.1101/2022.09.05.506620

Kanamycin Uptake into

Autor: Jayesh Arun, Bafna, Eulàlia, Sans-Serramitjana, Silvia, Acosta-Gutiérrez, Igor V, Bodrenko, Daniel, Hörömpöli, Anne, Berscheid, Heike, Brötz-Oesterhelt, Mathias, Winterhalter, Matteo, Ceccarelli

Publikováno v: ACS infectious diseases. 6(7)

Despite decades of therapeutic application of aminoglycosides, it is still a matter of debate if porins contribute to the translocation of the antibiotics across the bacterial outer membrane. Here, we quantified the uptake of kanamycin across the maj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::73c67cda6ecc2c64d0268f9a0445321e
https://pubmed.ncbi.nlm.nih.gov/32369342

Kanamycin Uptake into Escherichia coli Is Facilitated by OmpF and OmpC Porin Channels Located in the Outer Membrane

Autor: Matteo Ceccarelli, Daniel Hörömpöli, Eulàlia Sans-Serramitjana, Mathias Winterhalter, Silvia Acosta-Gutierrez, Heike Brötz-Oesterhelt, Anne Berscheid, Igor Bodrenko, Jayesh Arun Bafna

Publikováno v: ACS Infectious Diseases 6 (2020): 1855–1865. doi:10.1021/acsinfecdis.0c00102
info:cnr-pdr/source/autori:Bafna, Jayesh Arun; Sans-Serramitjana, Eulàlia; Acosta-Gutiérrez, Silvia; Bodrenko, Igor V.; Hörömpöli, Daniel; Berscheid, Anne; Brötz-Oesterhelt, Heike; Winterhalter, Mathias; Ceccarelli, Matteo/titolo:Kanamycin Uptake into Escherichia coli Is Facilitated by OmpF and OmpC Porin Channels Located in the Outer Membrane/doi:10.1021%2Facsinfecdis.0c00102/rivista:ACS Infectious Diseases/anno:2020/pagina_da:1855/pagina_a:1865/intervallo_pagine:1855–1865/volume:6

Despite decades of therapeutic application of aminoglycosides, it is still a matter of debate if porins contribute to the translocation of the antibiotics across the bacterial outer membrane. Here, we quantified the uptake of kanamycin across the maj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686b998de9e44a832025081e07bdb7e1
http://www.cnr.it/prodotto/i/436026