Paracetamol, ibuprofen and dexamethasone for pain treatment after total hip arthroplasty: protocol for the randomised, placebo-controlled, parallel 4-group, blinded, multicentre RECIPE trial

Autor: Janus Christian Jakobsen, Ole Mathiesen, Lars Hyldborg Lundstrøm, Søren Overgaard, Stig Brorson, Peter Lindholm, Daniel Hägi-Pedersen, Kasper Smidt Gasbjerg, Troels Haxholdt Lunn, Martin Lindberg-Larsen, Kasper Højgaard Thybo, Joakim Steiness, Ben Kristian Graungaard, Manuel Josef Bieder, Torben Beck, Michael Skettrup, Adam Gregers von Cappeln

Publikováno v: BMJ Open, Vol 12, Iss 9 (2022)

Introduction Multimodal analgesia with paracetamol, non-steroidal anti-inflammatory drug and glucocorticoid is recommended for hip arthroplasty, but with uncertain effects of the different combinations. We aim to investigate benefit and harm of diffe

Externí odkaz: https://doaj.org/article/84ff9a9258f84de1b43b07c465b17976

Nu-DESC DK: the Danish version of the nursing delirium screening scale (nu-DESC)

Autor: Daniel Hägi-Pedersen, Kasper Højgaard Thybo, Trine Hedegaard Holgersen, Joen Juel Jensen, Jean-David Gaudreau, Finn Michael Radtke

Publikováno v: BMC Nursing, Vol 16, Iss 1, Pp 1-6 (2017)

Abstract Background Delirium is one of the most common complications among elderly hospitalized patients, postoperative patients and patients on intensive care units with a prevalence between 11 and 80%. Delirium is associated with higher morbidity a

Externí odkaz: https://doaj.org/article/73aedeea8c93426cb62a77454365d193

Minimal important difference in opioid consumption based on adverse event reduction—A study protocol

Autor: Anders Peder Højer Karlsen, Casper Pedersen, Jens Laigaard, Kasper Højgaard Thybo, Kasper Smidt Gasbjerg, Anja Geisler, Troels Haxholdt Lunn, Daniel Hägi‐Pedersen, Janus Christian Jakobsen, Ole Mathiesen

Publikováno v: Karlsen, A P H, Pedersen, C, Laigaard, J, Thybo, K H, Gasbjerg, K S, Geisler, A, Lunn, T H, Hägi-Pedersen, D, Jakobsen, J C & Mathiesen, O 2023, ' Minimal important difference in opioid consumption based on adverse event reduction—A study protocol ', Acta Anaesthesiologica Scandinavica, vol. 67, no. 2, pp. 248-253 . https://doi.org/10.1111/aas.14175

Background: The patient-relevant minimal important difference for opioid consumption remains undetermined, despite its frequent use as primary outcome in trials on postoperative pain management. A minimal important difference is necessary to evaluate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03b0f9150547220bcd0c4a8b5746a0d
https://doi.org/10.1111/aas.14175

Pain treatment after total hip arthroplasty:Detailed statistical analysis plan for the RECIPE randomised clinical trial

Autor: Joakim Steiness, Daniel Hägi‐Pedersen, Troels H. Lunn, Anders K. Nørskov, Martin Lindberg‐Larsen, Ben K. Graungaard, Lars H. Lundstrøm, Peter Lindholm, Stig Brorson, Manuel J. Bieder, Torben Beck, Michael Skettrup, Adam G. von Cappeln, Kasper H. Thybo, Claus Varnum, Lina Pleckaitiene, Niels Anker Pedersen, Søren Overgaard, Ole Mathiesen, Janus C. Jakobsen

Publikováno v: Steiness, J, Hägi-Pedersen, D, Lunn, T H, Nørskov, A K, Lindberg-Larsen, M, Graungaard, B K, Lundstrøm, L H, Lindholm, P, Brorson, S, Bieder, M J, Beck, T, Skettrup, M, von Cappeln, A G, Thybo, K H, Varnum, C, Pleckaitiene, L, Pedersen, N A, Overgaard, S, Mathiesen, O & Jakobsen, J C 2023, ' Pain treatment after total hip arthroplasty : Detailed statistical analysis plan for the RECIPE randomised clinical trial ', Acta Anaesthesiologica Scandinavica, vol. 67, no. 3, pp. 372-380 . https://doi.org/10.1111/aas.14179

BACKGROUND: The RECIPE trial systematically investigates effects of different combinations of paracetamol, ibuprofen and dexamethasone for pain treatment after total hip arthroplasty. To preserve transparency, minimize risk of bias, and to prevent da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31bf19e132b0e5cf166588772c9eb6e
https://curis.ku.dk/portal/da/publications/pain-treatment-after-total-hip-arthroplasty(0d6846eb-75f8-480c-b0c2-368182f6ba0e).html

Effect of Dexamethasone on Myocardial Injury After Total Knee Arthroplasty: A Substudy of the Randomized Clinical DEX-2-TKA Trial

Autor: Asger K. Mølgaard, Kasper S. Gasbjerg, Christian S. Meyhoff, Troels H. Lunn, Janus C. Jakobsen, Ismail Gögenur, Ole Mathiesen, Daniel Hägi-Pedersen

Publikováno v: The American journal of medicine.

Myocardial injury after noncardiac surgery (MINS) carries a high postoperative mortality. In this preplanned, subgroup analysis of the randomized DEX-2-TKA Trial, we investigated the effect of dexamethasone versus placebo on the concentration of card

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d77c2755e2af7e6bd001d71846da44
https://pubmed.ncbi.nlm.nih.gov/36252718