Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Daniel H, Atchley"'
Autor:
Jacob B. Hatvany, Daniel H. Atchley, Landry K. Kamdem, Bill J. Gurley, Allison P. Garcia, Michael A. Murphy
Publikováno v:
Journal of clinical pharmacologyReferences. 60(2)
This pilot study examined how exemestane (an aromatase inhibitor [AI]) affected osteoprotegerin (OPG) urine concentrations in postmenopausal women. Exemestane (25 mg, single dose) was given to 14 disease-free women past menopause in this nonrandomize
Publikováno v:
The Journal of Clinical Pharmacology. 56:875-884
Exemestane is an aromatase inhibitor drug used for the treatment of hormone-dependent breast cancer. 17-hydroexemestane, the major and biologically active metabolite of exemestane in humans is eliminated via glucuronidation by the polymorphic UGT2B17
Publikováno v:
Journal of clinical pharmacy and therapeutics. 42(5)
SummaryWhat is known and objective OATP1B1 mediates the transport of a diverse range of amphiphilic organic compounds that include bile acids, steroid conjugates and hormones. This retrospective pharmacogenetic study was conducted to assess the impac
Autor:
Debra M. Niemeyer, James A. Swaby, James C McAvin, David E. Bowles, John R. Hickman, Daniel H. Atchley, Jamie A. Blow, Keith W. Blount, Miguel Quintana
Publikováno v:
Military Medicine. 170:1060-1065
An Aedes aegypti-specific, fluorogenic probe hydrolysis (Taq-Man), polymerase chain reaction assay was developed for real-time screening using a field-deployable thermocycler. Laboratory-based testing of A. aegypti, A. aegypti (Trinidad strain), Cule
Autor:
Francesco Wagner, Gabriel Virella, Elias M. Stephan, Maria F. Lopes-Virella, Daniel H. Atchley, Suzanne R. Thorpe, N. L. Alderson
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 3, Pp 487-493 (2003)
Advanced glycosylation end-products (AGEs) are believed to play a significant role in the development of vascular complications in diabetic patients. One such product, AGE-LDL, has been shown to be immunogenic. In this report, we describe the isolati
Autor:
Philippe Arnaud, Catherine Anne Morrison, Federica Azzimonti, David W. Boulton, C. Lindsay DeVane, Daniel H. Atchley, Seetal Dodd
Publikováno v:
Journal of Chromatography B. 784:33-38
Alpha1-acid glycoprotein is a plasma protein that exhibits both microheterogeneity and polymorphism. Its purification from human plasma is usually performed using a sequence of different fractionation steps. Here we report a one-step isolation techni
Publikováno v:
Diabetologia. 45:1562-1571
Aims/hypothesis. Oxidized LDL is immunogenic and immune complexes formed by oxidized LDL and corresponding antibodies are pro-atherogenic and pro-inflammatory. Considering that macroalbuminuria is a risk factor for coronary heart disease and that com
Autor:
Frederick J. Angulo, Matthew J. Darling, Jeffrey Fowler, Daniel H. Atchley, Russell P. DeFusco, Bruce R. Burnham
Publikováno v:
Journal of Herpetological Medicine and Surgery. 12:10-13
The increasing popularity of reptile ownership has been paralleled with an increasing incidence of human Salmonella infections. Antimicrobial agents have been suggested for the elimination of Salmonella carriage by reptiles. Nine green iguanas, Iguan
Autor:
Jason David, Craig D. Nowadly, Erik R. Demkowicz, Daniel H. Atchley, Melanie Grogger, Donald Veverka
Publikováno v:
Military medicine. 179(6)
Although advances in real-time polymerase chain reaction (PCR) technology and equipment have facilitated field research, only a limited selection of reagents do not require cold storage. This study explored the temperature stability of the commercial
Publikováno v:
Journal of microbiological methods. 68(3)
Typical real-time PCR methods used to identify Bacillus anthracis do not distinguish between viable and non-viable spores, which would be critical in any first response and remediation scenarios. This study combined both real-time PCR, using primers