Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Daniel Gygax"'
Autor:
Ana Catalán, Daniel Gygax, Leticia Rodríguez-Montes, Tjorven Hinzke, Katharina J. Hoff, Pablo Duchen
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Sexual dimorphism arises because of divergent fitness optima between the sexes. Phenotypic divergence between sexes can range from mild to extreme. Fireflies, bioluminescent beetles, present various degrees of sexual dimorphism, with species
Externí odkaz:
https://doaj.org/article/04e49f89638e466185ad1855a2c0e981
Autor:
Daniel Gygax, Kaspar Eigenmann, Christian Suter, Marianne Hürzeler, Ahmed Mahmoud, Johannes Mosbacher, Norbert Pöllinger
Publikováno v:
CHIMIA, Vol 77, Iss 9 (2023)
In this work, we investigated the technical feasibility of 'on-demand' production of selected drugs to cover their demand for a time window of 90 days. We focused on two sub-processes 'automated chemical synthesis' and 'formulation in micropellets' t
Externí odkaz:
https://doaj.org/article/8e31916eb0e74266b0fbddcfffbc94f4
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Pharmaceutical manufacturing relies on rigorous methods of quality control of drugs and in particular of the physico-chemical and functional characterizations of monoclonal antibodies. To that end, robust bioassays are very often limited to reporter
Externí odkaz:
https://doaj.org/article/7623c79e9e1547e8bbc48c41fffd818d
Autor:
Daniel Gygax
Publikováno v:
CHIMIA, Vol 73, Iss 1-2 (2019)
Externí odkaz:
https://doaj.org/article/da0102f2ba4d47b9b745d61fd7d60198
Autor:
Iwan Zimmermann, Pascal Egloff, Cedric AJ Hutter, Fabian M Arnold, Peter Stohler, Nicolas Bocquet, Melanie N Hug, Sylwia Huber, Martin Siegrist, Lisa Hetemann, Jennifer Gera, Samira Gmür, Peter Spies, Daniel Gygax, Eric R Geertsma, Roger JP Dawson, Markus A Seeger
Publikováno v:
eLife, Vol 7 (2018)
Mechanistic and structural studies of membrane proteins require their stabilization in specific conformations. Single domain antibodies are potent reagents for this purpose, but their generation relies on immunizations, which impedes selections in th
Externí odkaz:
https://doaj.org/article/0128ad13246b41d488888b761db2ce68
Autor:
Anissa Kempf, Bjoern Tews, Michael E Arzt, Oliver Weinmann, Franz J Obermair, Vincent Pernet, Marta Zagrebelsky, Andrea Delekate, Cristina Iobbi, Ajmal Zemmar, Zorica Ristic, Miriam Gullo, Peter Spies, Dana Dodd, Daniel Gygax, Martin Korte, Martin E Schwab
Publikováno v:
PLoS Biology, Vol 12, Iss 1, p e1001763 (2014)
Nogo-A is a membrane protein of the central nervous system (CNS) restricting neurite growth and synaptic plasticity via two extracellular domains: Nogo-66 and Nogo-A-Δ20. Receptors transducing Nogo-A-Δ20 signaling remained elusive so far. Here we i
Externí odkaz:
https://doaj.org/article/bf0435eb427c4707b9e3fffb96f095d4
Publikováno v:
CHIMIA, Vol 64, Iss 11 (2010)
A spectrophotometric assay based on a miniaturized 96-well plate device (IMAPlate) enables a rapid and simple screening of bioengineered recombinant lipases expressed and secreted by Saccharomyces cerevisiae. Starting from a colony, the test delivers
Externí odkaz:
https://doaj.org/article/d0f62eb83eb24f89a6aae1ede3cf655a
Publikováno v:
CHIMIA, Vol 64, Iss 7-8 (2010)
Externí odkaz:
https://doaj.org/article/3355d40924ad438aa123d2015a19ace5
Autor:
Roger Aeschbacher, Daniel Gygax
Publikováno v:
CHIMIA, Vol 60, Iss 5 (2006)
Chemistry is a science and an art. But it is not art for art's sake. Increasingly, chemistry is being used as a fundamental knowledge base to further innovations in bordering disciplines such as biology or medicine. At the School of Life Sciences in
Externí odkaz:
https://doaj.org/article/5b63e6701c914e168a1bc533c7f178e5
Publikováno v:
CHIMIA, Vol 58, Iss 5 (2004)
Substances that exert adverse effects on reproduction and fertility are a cause of concern. UV filters used in sunscreens and in the protection of materials may enter aquatic environments. Properties of UV filters such as environmental persistency an
Externí odkaz:
https://doaj.org/article/9b94a0bb484e440d9cc424f1017fd139