Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Daniel Gouy"'
Autor:
Nicole Bichet, Christophe Chesne, Georges de Sousa, Alain Fautrel, J. Pichon, M. Placidi, G. Lorenzon, C. Melcion, Marc Benicourt, Roger Rahmani, André Cordier, André Guillouzo, Robert Fournex, Françoise Braut, Daniel Gouy, Pascale Vintèzou, H. Hoellinger
Publikováno v:
Alternatives to Laboratory Animals. 21:281-284
A multicentre validation study of the acute in vitro cytotoxicities of 31 liquid or solid chemicals was carried out by six laboratories, using primary rat hepatocyte cultures as a model system. We report here a comparison of neutral red uptake IC50 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60c9bdf11cae57bc44e885f924604b94
https://doi.org/10.1177/026119299302100223
https://doi.org/10.1177/026119299302100223
Autor:
Marc Benicourt, H. Hoellinger, Robert Fournex, J. Pichon, F. Braut, Alain Fautrel, P. Vintezou, A.F. Peloux, M. Placidi, Daniel Gouy, R. Lounes, Jean-Paul Cano, Roger Rahmani, C. Melcion, Christophe Chesne, André Cordier, B. Vannier, I. Diarte, G. de Sousa, André Guillouzo, G. Lorenzon, Nicole Bichet
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 5(5-6)
A multicentre validation study of the acute in vitro cytotoxicity of drugs involving six French laboratories from INSERM or pharmaceutical companies has been carried out. Thirty liquid or solid chemicals such as antibiotics, anticancer drugs and solv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb29207d8e2a77f2d940b48f579d250d
https://pubmed.ncbi.nlm.nih.gov/20732074
https://pubmed.ncbi.nlm.nih.gov/20732074
Publikováno v:
Alternatives to Laboratory Animals. 20:8-26
The cytotoxicity of 30 chemicals was assessed in rat hepatocyte primary cultures using four methods: lactate dehydrogenase release, neutral red uptake, the MTT assay, and measurement of total protein content. Comparison of the data obtained in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b58e3aeef41b0dc2d040c8529b782351
https://doi.org/10.1177/026119299202000103
https://doi.org/10.1177/026119299202000103
Publikováno v:
Toxicology and Applied Pharmacology. 106:509-517
Primary cultures of rat and human hepatocytes were used in our in vitro studies for investigating species differences in the response to a peroxisome proliferating benzofuran derivative, benzbromarone. Cyanide-insensitive palmitoyl coenzyme A oxidati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::287c09b987a57107e57ecfedee18c08a
https://doi.org/10.1016/0041-008x(90)90345-u
https://doi.org/10.1016/0041-008x(90)90345-u
Autor:
Benoit Roig
About 4000 medical compounds are being used in the drugs applied today. It is estimated that worldwide consumption of active compounds amounts to some 100,000 tons or more per year. Consequently, there is a need to highlight the most important questi
