Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Daniel González Acosta"'
Autor:
Maria Dilia Palumbieri, Chiara Merigliano, Daniel González-Acosta, Danina Kuster, Jana Krietsch, Henriette Stoy, Thomas von Känel, Svenja Ulferts, Bettina Welter, Joël Frey, Cyril Doerdelmann, Andrea Sanchi, Robert Grosse, Irene Chiolo, Massimo Lopes
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Cells rapidly respond to replication stress actively slowing fork progression and inducing fork reversal. How replication fork plasticity is achieved in the context of nuclear organization is currently unknown. Using nuclear actin probes in
Externí odkaz:
https://doaj.org/article/9ce0187fdcd948fb8a159bba559a5fee
Autor:
Ann Liza Piberger, Akhil Bowry, Richard D. W. Kelly, Alexandra K. Walker, Daniel González-Acosta, Laura J. Bailey, Aidan J. Doherty, Juan Méndez, Joanna R. Morris, Helen E. Bryant, Eva Petermann
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Bulky DNA adducts are important replication-blocking lesions. Here the authors reveal that homologous recombination at bulky adducts in mammalian cells involves post-replicative gap repair in a PrimPol dependent manner.
Externí odkaz:
https://doaj.org/article/0f6811ec82d941be9a6362cf200f312d
Autor:
Maria Dilia Palumbieri, Chiara Merigliano, Daniel González Acosta, Thomas von Känel, Bettina Welter, Henriette Stoy, Jana Krietsch, Svenja Ulferts, Andrea Sanchi, Robert Grosse, Irene Chiolo, Massimo Lopes
Publikováno v:
bioRxiv
Cells rapidly respond to replication stress actively slowing fork progression and inducing fork reversal. How replication fork plasticity is achieved in the context of nuclear organization is currently unknown. Using nuclear actin probes in living an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859d8a9fd3cbd8f88f59be0633e641af
https://doi.org/10.1101/2023.03.24.534097
https://doi.org/10.1101/2023.03.24.534097
Autor:
Kurt Jacobs, Cyril Doerdelmann, Jana Krietsch, Daniel González-Acosta, Nicolas Mathis, Saul Kushinsky, Estrella Guarino, Carmen Gómez-Escolar, Dolores Martinez, Jonas A. Schmid, Peter J. Leary, Raimundo Freire, Almudena R. Ramiro, Christine M. Eischen, Juan Mendez, Massimo Lopes
Publikováno v:
Mol Cell
Stem cell division is linked to tumorigenesis by yet-elusive mechanisms. The hematopoietic system reacts to stress by triggering hematopoietic stem and progenitor cell (HSPC) proliferation, which can be accompanied by chromosomal breakage in activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7beccda09e45b21eae3c4f4c087add
https://hdl.handle.net/20.500.12105/15286
https://hdl.handle.net/20.500.12105/15286
Autor:
Susana Llanos, Karun Mutreja, Patricia Ubieto-Capella, Samuel Miguez, Daniel González-Acosta, Juan Méndez, Fernando García, Elena Blanco-Romero, Javier Munoz, Luis Blanco, Massimo Lopes
Publikováno v:
The EMBO Journal
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
DNA interstrand crosslinks (ICLs) induced by endogenous aldehydes or chemotherapeutic agents interfere with essential processes such as replication and transcription. ICL recognition and repair by the Fanconi Anemia pathway require the formation of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a717473159ed5bb2d03523f9e1edcb69
https://doi.org/10.15252/embj.2020106355
https://doi.org/10.15252/embj.2020106355
Autor:
Juan Méndez, Luis Blanco, Massimo Lopes, Karun Mutreja, Javier Munoz, Samuel Miguez, Fernando García, Daniel González-Acosta, Elena Blanco-Romero, Susana Llanos
Interstrand crosslinks (ICLs) are DNA lesions frequently induced by chemotherapy that interfere with essential processes such as replication and transcription. ICL repair may be initiated by the convergence of two replication forks at the crosslink,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34915c91c74c5dcb6b47d86eeb4f2d01
https://doi.org/10.1101/2020.05.19.104729
https://doi.org/10.1101/2020.05.19.104729
Autor:
Patricia A. Calvo, Daniel González-Acosta, Marcos Díaz, Juan Méndez, Alberto Díaz-Talavera, María I. Martínez-Jiménez, Susana Guerra, Guillermo Sastre-Moreno, Luis Blanco, Luis Blanco-Franco
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
PrimPol is a human primase/polymerase specialized in re-starting stalled forks by repriming beyond lesions such as pyrimidine dimers, and replication-perturbing structures including G-quadruplexes and R-loops. Unlike most conventional primases, PrimP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11e638af8e6b5ba8a73bca8c54e2000
http://europepmc.org/articles/PMC6362072
http://europepmc.org/articles/PMC6362072
Autor:
Tania López‐Briones, Daniel González-Acosta, Ignacio Moreno de Alborán, Alfonsina Trento, Sara Rodriguez-Acebes, Sara Roman-Garcia, Carlos Torroja, Mercedes Pérez‐Olivares, Juan Méndez, Dolores Martinez, David Fernandez-Antoran, Yolanda R. Carrasco
Publikováno v:
EMBO reports. 19
The Myc family of oncogenic transcription factors regulates myriad cellular functions. Myc proteins contain a basic region/helix‐loop‐helix/leucine zipper domain that mediates DNA binding and heterodimerization with its partner Max. Among the Myc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07187ccf4c18782af598103c9a3f71a4
https://doi.org/10.15252/embr.201845770
https://doi.org/10.15252/embr.201845770