Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Daniel Gonnermann"'
Autor:
Daniel Gonnermann, Hans-Heinrich Oberg, Marcus Lettau, Matthias Peipp, Dirk Bauerschlag, Susanne Sebens, Dieter Kabelitz, Daniela Wesch
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Pancreatic ductal adenocarcinoma (PDAC) is characterized by an immunosuppressive tumor microenvironment with a dense desmoplastic stroma. The expression of β-galactoside-binding protein galectin-3 is regarded as an intrinsic tumor escape mechanism f
Externí odkaz:
https://doaj.org/article/753b3f2798a840c082342c236fa29ca8
Autor:
Hannah Jonescheit, Hans-Heinrich Oberg, Daniel Gonnermann, Martin Hermes, Vjola Sulaj, Christian Peters, Dieter Kabelitz, Daniela Wesch
Publikováno v:
Cells, Vol 9, Iss 5, p 1140 (2020)
Background: Pancreatic ductal adenocarcinoma (PDAC) is a malignant gastrointestinal disease. The enzyme indoleamine-2,3-dioxgenase (IDO) is often overexpressed in PDAC and its downstream metabolite kynurenine has been reported to inhibit T cell activ
Externí odkaz:
https://doaj.org/article/f26b8c56bf9e453fb1dd8a9a502b31c2
Autor:
Hans H. Oberg, Christian Kellner, Daniel Gonnermann, Susanne Sebens, Dirk Bauerschlag, Martin Gramatzki, Dieter Kabelitz, Matthias Peipp, Daniela Wesch
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
An enhanced expression of human epidermal growth factor receptor 2 (HER2, ErbB2) often occurs in an advanced stage of breast, ovarian, gastric or esophageal cancer, and pancreatic ductal adenocarcinoma (PDAC). Commonly, HER2 expression is associated
Externí odkaz:
https://doaj.org/article/3e4dc252034d4a9ba13cafe188a5ed30
Autor:
Dieter Kabelitz, Daniela Wesch, Matthias Peipp, Jörg Weimer, Dirk Bauerschlag, Lisa Janitschke, Vjola Sulaj, Norbert Arnold, Nina Hedemann, Daniel Gonnermann, Hans-Heinrich Oberg
Publikováno v:
Journal of Leukocyte Biology
Epithelial ovarian cancer displays the highest mortality of all gynecological tumors. A relapse of the disease even after successful surgical treatment is a significant problem. Resistance against the current platinum‐based chemotherapeutic standar
Autor:
Dirk Bauerschlag, Daniela Wesch, Daniel Gonnermann, Dieter Kabelitz, Susanne Sebens, Marcus Lettau, Hans-Heinrich Oberg, Matthias Peipp
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Pancreatic ductal adenocarcinoma (PDAC) is characterized by an immunosuppressive tumor microenvironment with a dense desmoplastic stroma. The expression of β-galactoside-binding protein galectin-3 is regarded as an intrinsic tumor escape mechanism f
Autor:
Vjola Sulaj, Hans-Heinrich Oberg, Hannah Jonescheit, Daniel Gonnermann, Martin Hermes, Christian J. Peters, Dieter Kabelitz, Daniela Wesch
Publikováno v:
Cells, Vol 9, Iss 1140, p 1140 (2020)
Cells
Volume 9
Issue 5
Cells
Volume 9
Issue 5
Background: Pancreatic ductal adenocarcinoma (PDAC) is a malignant gastrointestinal disease. The enzyme indoleamine-2,3-dioxgenase (IDO) is often overexpressed in PDAC and its downstream metabolite kynurenine has been reported to inhibit T cell activ
Autor:
Ole Ammerpohl, Henrike Bruckmueller, Daniel Gonnermann, Meike Kaehler, Oliver Bruhn, Daniela Wesch, Johanna Ruemenapp, Ingolf Cascorbi, Sierk Haenisch, Inga Nagel
Publikováno v:
Oncotarget
BCR-ABL-independent resistance against tyrosine kinase inhibitor is an emerging problem in therapy of chronic myeloid leukemia. Such drug resistance can be linked to dysregulation of ATP-binding cassette (ABC)-transporters leading to increased tyrosi
Autor:
Susanne Sebens, Dirk Bauerschlag, Martin Gramatzki, Matthias Peipp, Hans Heinrich Oberg, Dieter Kabelitz, Daniela Wesch, Christian Kellner, Daniel Gonnermann
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
An enhanced expression of human epidermal growth factor receptor 2 (HER2, ErbB2) often occurs in an advanced stage of breast, ovarian, gastric or esophageal cancer and pancreatic ductal adenocarcinoma (PDAC). Commonly, HER2 expression is associated w
Autor:
Christian Peters, Susanne Sebens, Dieter Kabelitz, Christian Kellner, Matthias Peipp, Daniela Wesch, Hans-Heinrich Oberg, Daniel Gonnermann
Publikováno v:
Cellular Immunology. 296:41-49
Bispecific antibodies have been successfully introduced into clinical application. γδ T cells are of special interest for tumor immunotherapy, due to their recognition of pyrophosphates that are overproduced by many tumor cells resulting in HLA-non
Autor:
Patrik Theodor Nerdal, Hristo Zlatev, Ottmar Janssen, Jorma A. Määttä, Christian Peters, Daniel Gonnermann, Elgar Susanne Quabius, Dieter Kabelitz, Sofia Sousa, Marcus Lettau, Seppo Auriola, Daniel Olive, Hans-Heinrich Oberg
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 197(8)
Human Vγ9Vδ2 T cells recognize in a butyrophilin 3A/CD277–dependent way microbial (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP) or endogenous pyrophosphates (isopentenyl pyrophosphate [IPP]). Nitrogen-bisphosphonates such as zoledronic