Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Daniel Gironés"'
Publikováno v:
Molecules, Vol 29, Iss 17, p 4047 (2024)
Orthoflaviviruses, including zika (ZIKV), West Nile (WNV), and dengue (DENV) virus, induce severely debilitating infections and contribute significantly to the global disease burden, yet no clinically approved antiviral treatments exist. This review
Externí odkaz:
https://doaj.org/article/0c2077739ff947db96ae0c5d192207dc
Autor:
Mark Damen, Mario A. Izidoro, Debora N. Okamoto, Lilian C. G. Oliveira, Helene I. V. Amatdjais-Groenen, Stijn F. M. van Dongen, Koen W. R. van Cleef, Ronald P. van Rij, Cindy E. J. Dieteren, Daniel Gironés, Bernd N. M. van Buuren, Byron E. E. Martina, Albert D. M. E. Osterhaus, Luiz Juliano, Bob J. Scholte, Martin C. Feiters
Publikováno v:
Molecules, Vol 27, Iss 10, p 3217 (2022)
Dengue is an important arboviral infectious disease for which there is currently no specific cure. We report gemini-like (geminoid) alkylated amphiphilic peptides containing lysines in combination with glycines or alanines (C15H31C(O)-Lys-(Gly or Ala
Externí odkaz:
https://doaj.org/article/d084e2f6349a407ca6f90b3ddaeb881b
Publikováno v:
European Journal of Organic Chemistry, 2012, 4740-4750
European Journal of Organic Chemistry, 2012, 31, pp. 4740-4750
European Journal of Organic Chemistry, 2012, 31, pp. 4740-4750
Conveniently protected neamine analogues were synthesized with a free 2′-OH group for further functionalization. An approach was investigated involving a stereoselective α-glycosidation reaction of 3,4-O-dimethoxybutanediyl-2-O-silyl protected thi