Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Daniel Gebhard"'
Publikováno v:
Bio-Protocol, Vol 11, Iss 6 (2021)
7,8-dihydro-8-oxoguanine (8-oxoG) is one of the most common and mutagenic oxidative DNA damages induced by reactive oxygen species (ROS). Since ROS is mainly produced in the inner membranes of the mitochondria, these organelles and especially the mit
Externí odkaz:
https://doaj.org/article/826153ac7a204fa9a6d6b245d26c7371
Publikováno v:
Bio-Protocol, Vol 9, Iss 5 (2019)
Skin cells are constantly exposed to environmental influences such as air pollution, chemicals, pathogens and UV radiation. UV radiation can damage different biological structures, but most importantly cellular DNA. Mitochondria contain their own gen
Externí odkaz:
https://doaj.org/article/904baab4dfa2421fb6e8cd091f4d571e
Publikováno v:
Journal of Aging Research, Vol 2018 (2018)
The process of aging is characterized by the increase of age-associated disorders as well as severe diseases. Due to their role in the oxidative phosphorylation and thus the production of ATP which is crucial for many cellular processes, one reason f
Externí odkaz:
https://doaj.org/article/e717a2f6da104be2ad63e93c5d300f7e
Publikováno v:
Bio-Protocol, Vol 6, Iss 15 (2016)
The filamentous ascomycete Fusarium graminearum is the causal agent of Fusarium head blight, a devastating disease of cereals with a worldwide distribution. Fusarium graminearum infections result in a quantitative yield reduction by impairing the gro
Externí odkaz:
https://doaj.org/article/63c482e5dfc8418da4d78d59dacacaa1
Autor:
Prashant Jha, Daniel Gebhard
Publikováno v:
Pediatric Infectious Disease Journal. 39:e464-e466
We are presenting a case of 4-years-old previously healthy male with coma, severe acute hepatitis and multiorgan failure in presence of Influenza infection. Literature review highlighted an immune-mediated pathophysiology for such presentations so th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddfc5d66f3336eb52a576fc2bc56601
https://doi.org/10.1097/inf.0000000000002892
https://doi.org/10.1097/inf.0000000000002892
Autor:
Daniel Gebhard, Melissa Frei-Jones
Publikováno v:
Benign Hematologic Disorders in Children ISBN: 9783030499792
Acquired disorders of coagulation, including both primary and secondary hemostasis, commonly occur in the critically ill neonate or child. In both the neonatal intensive care unit (NICU) and the pediatric intensive care unit (PICU), clinicians are co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2f2c52577313393d96112dd43cbf86e
https://doi.org/10.1007/978-3-030-49980-8_18
https://doi.org/10.1007/978-3-030-49980-8_18
Autor:
Aswin Mangerich, Alexander Bürkle, Tabea Zubel, Kirsten Jander, Jelena Fix, Jan M. F. Fischer, Irmela Ruth Eva Antonie Trussina, Jörg Bergemann, Daniel Gebhard
Publikováno v:
Archives of Toxicology
Poly(ADP-ribosyl)ation (PARylation) is a complex and reversible posttranslational modification catalyzed by poly(ADP-ribose)polymerases (PARPs), which orchestrates protein function and subcellular localization. The function of PARP1 in genotoxic stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96368cee9b3c3a16b08817047b20c5a4
https://doi.org/10.1007/s00204-017-2115-6
https://doi.org/10.1007/s00204-017-2115-6
Autor:
Jörg Bergemann, Julia Schon, Heiko van Beek, Vivien Nöth, Daniel Schniertshauer, Daniel Gebhard
Publikováno v:
DNA Repair. 87:102784
The DNA of human cells suffers about 1.000–100.000 oxidative lesions per day. One of the most common defects in this category is represented by 7,8-dihydro-8-oxoguanine. There are numerous exogenous effects on DNA that induce the intracellular gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1548ffbc4d92c0792ae7290dc47ea9c
https://doi.org/10.1016/j.dnarep.2019.102784
https://doi.org/10.1016/j.dnarep.2019.102784
Autor:
Daniel Gebhard, Birgit Hadeler, Jörg Bergemann, Jörg Bormann, Cathrin Kröger, Thomas Tumforde, Reinhard Lieberei, Wilhelm Schäfer, Jakob Bönnighausen
Publikováno v:
Molecular Microbiology. 98:1115-1132
The cereal pathogen Fusarium graminearum threatens food and feed production worldwide. It reduces the yield and poisons the remaining kernels with mycotoxins, notably deoxynivalenol (DON). We analyzed the importance of gamma-aminobutanoic acid (GABA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8a6069a3188536e7846c5527b9b59a9
https://doi.org/10.1111/mmi.13203
https://doi.org/10.1111/mmi.13203
Autor:
Sascha Beneke, Aswin Mangerich, Sebastian Veith, Martin Scheffner, Jan M. F. Fischer, Arthur Fischbach, Elisa Ferrando-May, Alexander Bürkle, Daniel Gebhard, Jörg Bergemann, Alfred Leitenstorfer, Oliver Popp
Publikováno v:
The Febs Journal
Poly(ADP-ribose) (PAR) is a complex and reversible post-translational modification that controls protein function and localization through covalent modification of, or noncovalent binding to target proteins. Previously, we and others characterized th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b773c5f99de49e6a5c93dff93a1070
https://doi.org/10.1111/febs.12885
https://doi.org/10.1111/febs.12885