Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniel Garafola"'
Autor:
Irena Adkins, Emily Kuiper, Kathleen Whiteman, Daniel Garafola, Pratirodh Koirala, Shannon Smith, Klara Danova, Ekaterina Simonova, Lenka Palova Jelinkova, Amy Jensen-Smith
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/78c1b034b1264883b2328f8ae32d7d19
Autor:
Beth E. Grace, Coralie M. Backlund, Duncan M. Morgan, Byong H. Kang, Nishant K. Singh, Brooke D. Huisman, C. Garrett Rappazzo, Kelly D. Moynihan, Laura Maiorino, Connor S. Dobson, Taeyoon Kyung, Khloe S. Gordon, Patrick V. Holec, Overbeck C. Takou Mbah, Daniel Garafola, Shengwei Wu, J. Christopher Love, K. Dane Wittrup, Darrell J. Irvine, Michael E. Birnbaum
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
While immune checkpoint blockade results in durable responses for some patients, many others have not experienced such benefits. These treatments rely upon reinvigorating specific T cell-antigen interactions. However, it is often unknown what antigen
Externí odkaz:
https://doaj.org/article/974ae2fd3083480d86e6565189e0552e
Autor:
Darrell J. Irvine, Heikyung Suh, Nikki Thai, Josetta Adams, Nathan Donahue, Ayush Thomas, Shengwei Wu, Yash Agarwal, Daniel Garafola, Lauren E. Milling
Supplementary Data from Neoadjuvant STING Activation, Extended Half-life IL2, and Checkpoint Blockade Promote Metastasis Clearance via Sustained NK-cell Activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891b0f6defd2cb1b5a6d9b3a969c2253
https://doi.org/10.1158/2326-6066.22544181.v1
https://doi.org/10.1158/2326-6066.22544181.v1
Autor:
Coralie M. Backlund, Rebecca L. Holden, Kelly D. Moynihan, Daniel Garafola, Charlotte Farquhar, Naveen K. Mehta, Laura Maiorino, Sydney Pham, J. Bryan Iorgulescu, David A. Reardon, Catherine J. Wu, Bradley L. Pentelute, Darrell J. Irvine
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Peptide-based cancer vaccines are widely investigated in the clinic but exhibit modest immunogenicity. One approach that has been explored to enhance peptide vaccine potency is covalent conjugation of antigens with cell-penetrating peptides (CPPs), l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a26d5458dc6c620d6cf56669cbbeb9e
https://doi.org/10.1073/pnas.2204078119
https://doi.org/10.1073/pnas.2204078119
Autor:
Daniel Garafola, R. John Collier, Bradley L. Pentelute, Hidde L. Ploegh, Carly K. Schissel, Alexander R. Loftis, Andrei Loas, Genwei Zhang, Anthony J. Quartararo, Coralie Backlund, Novalia Pishesha, Darrell J. Irvine
Targeting of antigens to erythrocytes can be used to selectively mitigate their immunogenicity, but the methods to equip a variety of cargoes with erythrocyte-targeting properties are limited. Here we identified a D-peptide that targets murine erythr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a507e94dc21a6673c687703ad1c1b3cc
https://doi.org/10.1101/2020.07.15.203331
https://doi.org/10.1101/2020.07.15.203331
Autor:
Wuhbet Abraham, Naveen K. Mehta, Murillo Silva, Simon Liang, Jason Y. Chang, Michael Fichter, Darrell J. Irvine, Nikki Thai, Leyuan Ma, K. Dane Wittrup, Benjamin J. Cossette, Chensu Wang, Tanmay Dichwalkar, Daniel Garafola, Na Li, Sudha Kumari, Angela Q. Zhang
Chimeric antigen receptor-T cell (CAR-T) therapy has been effective in the treatment of hematologic malignancies, but it has shown limited efficacy against solid tumors. Here we demonstrate an approach to enhancing CAR-T function in solid tumors by d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4527c395376aa061e41dfa8ec52998d0
https://europepmc.org/articles/PMC6800571/
https://europepmc.org/articles/PMC6800571/