Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Daniel Galtier"'
Autor:
Mostapha Matrougui, Paul J. Schaeffer, Zsolt Bocskei, Janine Lorrain, Jean-Marc Herbert, Christopher N. Berry, Jean-Claude Jetha, Stephen E. O'Connor, Lassalle Gilbert, Jean-Michel Altenburger, Jean-Pascal Herault, Catherine Lunven, Daniel Galtier
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:1713-1730
SSR182289A 1 is the result of a rational optimisation process leading to an orally active thrombin inhibitor. The struc- ture incorporates an original 2-(acetylamino)-(1,1 0 -biphenyl)-3-sulfonyl N-terminal motif, a central l-Arg surrogate carrying a
Publikováno v:
Neurobiology of Disease, Vol 128, Iss , Pp 3-8 (2019)
In the last decade, scientific and clinical interest in the pedunculopontine nucleus (PPN) has grown dramatically. This growth is largely a consequence of experimental work demonstrating its connection to the control of gait and of clinical work impl
Externí odkaz:
https://doaj.org/article/249396c5ad78477dae5802dd8ed45844
Autor:
Daniel Galtier, Jean Benoit, Remy Guegan, Joseph Millan, Jacques Clement, Michel Beaumont, Michel Vedel, Joseph Diaz, Claude Muneaux, Robert Schwyzer, Christian Fauchard, Yvette Muneaux
Publikováno v:
Bioorganic Chemistry. 8:429-442
A large-scale synthesis of somatostatin was developed. A stepwise C → N approach in solution was used, employing N (α)-t-butoxycarbonyl amino acid active esters. The scheme of semipermanent protection utilized 2-(methylsulfonyl)-ethoxycarbonyl for