Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Daniel G. Kavanagh"'
Autor:
Nina Bhardwaj, Rajesh T. Gandhi, Mark A. Brockman, Bruce D. Walker, Anna Pavlick, Sylvia Adams, David O'Neill, Dusan Bogunovic, Galit Alter, Daniel G. Kavanagh, Kira Minkis
Supplementary Table 2 from Type 2 Bias of T Cells Expanded from the Blood of Melanoma Patients Switched to Type 1 by IL-12p70 mRNA–Transfected Dendritic Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a65365949a729d9564dcbe85a364649
https://doi.org/10.1158/0008-5472.22376547.v1
https://doi.org/10.1158/0008-5472.22376547.v1
Autor:
Nina Bhardwaj, Rajesh T. Gandhi, Mark A. Brockman, Bruce D. Walker, Anna Pavlick, Sylvia Adams, David O'Neill, Dusan Bogunovic, Galit Alter, Daniel G. Kavanagh, Kira Minkis
Supplementary Table 1 from Type 2 Bias of T Cells Expanded from the Blood of Melanoma Patients Switched to Type 1 by IL-12p70 mRNA–Transfected Dendritic Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffb8077ee6b6aa5d89ae1286a426f03
https://doi.org/10.1158/0008-5472.22376550.v1
https://doi.org/10.1158/0008-5472.22376550.v1
Autor:
Rachel Lubong Sabado, Daniel G Kavanagh, Daniel E Kaufmann, Karlhans Fru, Ethan Babcock, Eric Rosenberg, Bruce Walker, Jeffrey Lifson, Nina Bhardwaj, Marie Larsson
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4256 (2009)
The requirements for priming of HIV-specific T cell responses initially seen in infected individuals remain to be defined. Activation of T cell responses in lymph nodes requires cell-cell contact between T cells and DCs, which can give concurrent act
Externí odkaz:
https://doaj.org/article/3027ea93603042d5860ae73c789b289c
Autor:
Kholiswa C Ngumbela, Kieran P Ryan, Rohini Sivamurthy, Mark A Brockman, Rajesh T Gandhi, Nina Bhardwaj, Daniel G Kavanagh
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2356 (2008)
The sequences of wild-isolate strains of Human Immunodeficiency Virus-1 (HIV-1) are characterized by low GC content and suboptimal codon usage. Codon optimization of DNA vectors can enhance protein expression both by enhancing translational efficienc
Externí odkaz:
https://doaj.org/article/99243236be894926a6c9d4835523ca28
Autor:
Amy Sbrolla, Anna P. McLean, Rajesh T. Gandhi, Bruce D. Walker, Nicole McBrine, Douglas S. Kwon, Filippos Porichis, Janet Shopis, Dan H. Barouch, Lauren Peter, Theresa Flynn, Nina Bhardwaj, Daniel G. Kavanagh, Eric A. Macklin, Daniel Kaufmann
Publikováno v:
Journal of Acquired Immune Deficiency Syndromes (1999)
Background: HIV-1 eradication may require reactivation of latent virus along with stimulation of HIV-1-specific immune responses to clear infected cells. Immunization with autologous dendritic cells (DCs) transfected with viral mRNA is a promising st
Autor:
Yang Xu, Pauline Gourdain, Mariko Shimada, Ellen Duong, Nicole Y. Lai, Daniel G. Kavanagh, Edith Bracho-Sanchez, Marijana Rucevic, Jens Dinter, Musie Ghebremichael, Sylvie Le Gall, Paul Liebesny
Publikováno v:
The Journal of Immunology. 193:4322-4334
Dendritic cells (DCs), macrophages (MPs), and monocytes are permissive to HIV. Whether they similarly process and present HIV epitopes to HIV-specific CD8 T cells is unknown despite the critical role of peptide processing and presentation for recogni
Simultaneous TCR and CD244 Signals Induce Dynamic Downmodulation of CD244 on Human Antiviral T Cells
Autor:
Daniel G. Kavanagh, Anna P. McLean, Yovana Pacheco, Filippos Porichis, Janine Rohrbach, Daniel Kaufmann
Publikováno v:
The Journal of Immunology. 191:2072-2081
Various cosignaling molecules on T cells can contribute to activation, inhibition, or exhaustion, depending on context. The surface receptor signaling lymphocytic activation molecule (SLAM) family receptor CD244 (2B4/SLAMf4) has been shown to be capa
Publikováno v:
PubMed Central
Biodegradable core−shell structured nanoparticles with a poly(β-amino ester) (PBAE) core enveloped by a phospholipid bilayer shell were developed for in vivo mRNA delivery with a view toward delivery of mRNA-based vaccines. The pH-responsive PBAE
Autor:
Bruce D. Walker, Thomas J. Diefenbach, Filippos Porichis, Marta Rodriguez-Garcia, Daniel G. Kavanagh, Olivier G. de Jong, Daniel Kaufmann, Jeffrey D. Lifson, Karen Levi, Gordon J. Freeman
Publikováno v:
Journal of Leukocyte Biology. 89:507-515
PD-1 plays an important role in T cell exhaustion during HIV infection. PD-1 has two ligands: PD-L1, expressed on hematopoietic and nonhematopoietic cells, and PD-L2, limited to DCs and macrophages. Little is known about PD-L1 expression and regulati
Autor:
Bruce D. Walker, Anna C. Pavlick, Rajesh T. Gandhi, Mark A. Brockman, Daniel G. Kavanagh, Sylvia Adams, Kira Minkis, Galit Alter, Nina Bhardwaj, David O'Neill, Dusan Bogunovic
Publikováno v:
Cancer Research. 68:9441-9450
Melanoma patients may exhibit a TH2-skewed cytokine profile within blood and tumor-infiltrating lymphocytes. Therapies that induce beneficial TH1-type tumor-specific immune responses, therefore, are highly desirable. Dendritic cells (DC) are widely u