Výsledky vyhledávání - "Daniel G. Brenner"

Modeling Student Learning Behavior Patterns in an Online Science Inquiry Environment

Autor: Marina Varfolomeeva, Daniel G. Brenner, Kim Luttgen, Michael J. Timms, Perman Gochyyev, Andrew Grillo-Hill, Bryan J. Matlen

Publikováno v: Technology, Knowledge and Learning. 22:405-425

This study investigated how the frequency and level of assistance provided to students interacted with prior knowledge to affect learning in the Voyage to Galapagos (VTG) science inquiry-learning environment. VTG provides students with the opportunit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bfd73c0d2b38599bd3bbe9fca5bf9cf8
https://doi.org/10.1007/s10758-017-9325-0

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Simulations for Supporting and Assessing Science Literacy

Autor: Matt D. Silberglitt, Daniel G. Brenner, Mark T. Loveland, Barbara C. Buckley, Edys S. Quellmalz

Simulations have become core supports for learning in the digital age. For example, economists, mathematicians, and scientists employ simulations to model complex phenomena. Learners, too, are increasingly able to take advantage of simulations to und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f229c3082bac5f93395a0e44116665b
https://doi.org/10.4018/978-1-4666-9441-5.ch008

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Production of Antigen-Specific Human Antibodies from Mice Engineered with Human Heavy and Light Chain YACsa

Autor: Daniel J. Capon, Sue Klapholz, Joanna F. Hales, Michael Mendez, Catherine E. Maynard-Currie, Donna M. Louie, Hitoshi Sasai, Larry L. Green, Yongjun Zeng, Nathaniel E. David, Dan Garza, Ryan Mcguinness, Margaret C. Hardy, Aya Jakobovits, Hirohisa Tsuda, Douglas H. Smith, Hadi Abderrahim, Masato Noguchi, Daniel G. Brenner

Publikováno v: Annals of the New York Academy of Sciences. 764:525-535

Our paper describes the introduction of large fragments of both the human heavy and light chain Ig genes into the mouse germline to create a mouse strain capable of producing a broad repertoire of antigen-specific, fully human antibodies. The human i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906d42de73d62197e3db33e238d585dc
https://doi.org/10.1111/j.1749-6632.1995.tb55878.x

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THE INFLAMMASOME PATHWAY IS ASSOCIATED WITH ADVERSE VENTRICULAR REMODELING FOLLOWING TRANSCATHETER AORTIC VALVE REPLACEMENT

Autor: Francois Haddad, Michael P. Fischbein, Daniel G. Brenner, D. Craig Miller, Ingela Schnittger, William F. Fearon, Ryan O’Malley, Juyong Brian Kim, Catherine Dao, Alan C. Yeung, Tatiana Kouznetsova, Yukari Kobayashi, Kegan J. Moneghetti, Anson M. Lee, Joseph C. Wu, David Liang

Publikováno v: Journal of the American College of Cardiology. 69:1040

Background: Aortic stenosis (AS) results in progressive ventricular remodeling and heart failure. There is strong evidence that inflammatory cytokines play a key role in this maladaptive process, however, it is unclear how they affect the ventricular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc3d353948f96d9a1e011074beaa659f
https://doi.org/10.1016/s0735-1097(17)34429-7

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A Web-based System to Support Inquiry Learning - Towards Determining How Much Assistance Students Need

Autor: Michael J. Timms, David H. Brown, Doug Weihnacht, Bruce M. McLaren, Kim Luttgen, Andrew Grillo-Hill, Daniel G. Brenner

Publikováno v: CSEDU (1)

How much assistance should be provided to students as they learn with educational technology? Providing help allows students to proceed when struggling, yet can depress their motivation to learn independently. Assistance withholding encourages studen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1710d6120b54eac7c5619783c4757dad
https://doi.org/10.5220/0004810100430052

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Effect of Recombinant Neutral Endopeptidase (EC 3.4.24.11) on Neuropeptide-Mediated Nasal Fluid Secretion and Plasma Exudation in the Rat

Autor: Daniel G. Brenner, Malin Josefsson, Magnus Becker, Fritz Stroman, Göran Petersson

Publikováno v: American Journal of Rhinology. 12:135-142

The nasal mucosa harbors sensory nerves containing neuropeptides such as substance P (SP), which are released by capsaicin. The neuropeptides are degraded by peptidases, e.g., neutral endopeptidase (NEP) that is present in the nasal mucosa. We studie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c52f971154a8b3d22a1eec266df44b7
https://doi.org/10.2500/105065898781390244

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CD10/neutral endopeptidase 24.11 is phosphorylated by casein kinase II and coassociates with other phosphoproteins including the lyn src- related kinase

Autor: Margaret A. Shipp, Ramesh K. Ganju, Rozalia G. Shpektor, Daniel G. Brenner

Publikováno v: Blood. 88:4159-4165

CD10/neutral endopeptidase 24.11 (NEP) regulates peptidemediated proliferation of lymphoid progenitors and certain epithelial cells and is itself regulated by cellular proliferation. To further characterize mechanisms by which cell-surface signaling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e68585abc5bf4df7ef9fbd54791a590
https://doi.org/10.1182/blood.v88.11.4159.4159

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Analysis of homozygous mutant chimeric mice: deletion of the immunoglobulin heavy-chain joining region blocks B-cell development and antibody production

Autor: Jacqueline L. Kennedy, Denise E. Casentini-Borocz, Ryan P. McGuinness, Joanna F. Hales, German J. Vergara, Daniel G. Brenner, Aya Jakobovits, Gillis R. Otten

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 90(6)

Using a recently described method for efficiently deriving homozygous targeted alleles in embryonic stem cells, we produced chimeric mice whose tissues were derived partially from embryonic stem cells bearing homozygous deletion of the mouse immunogl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426a1357ad0f3733adf5879d33afd774
https://pubmed.ncbi.nlm.nih.gov/8460171

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Rapid two-stage polymerase chain reaction amplification of chromosomal DNA segments in lysates made from monolayer cultures attached to microcarrier beads

Autor: Stanley N. Cohen, Daniel G. Brenner, Sue Lin-Chao

Publikováno v: Gene. 93(2)

We describe a method for the rapid two-stage amplification and detection by ethidium bromide staining of chromosomal nucleotide (nt) sequences in lysates made directly from anchorage-dependent cells attached to microcarrier beads. The procedure circu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e31fa381f3026118e319c4118f0c22
https://pubmed.ncbi.nlm.nih.gov/2227440

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