Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Daniel Fourmy"'
Autor:
Adrià Sánchez-Morales, Véronique Gigoux, Minos-Timotheos Matsoukas, Laura Perez-Benito, Daniel Fourmy, Ramón Alibes, Félix Busqué, Arnau Cordomí, Jean-Marc Devaud
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Honey bees are of great economic and ecological importance, but are facing multiple stressors that can jeopardize their pollination efficiency and survival. Therefore, understanding the physiological bases of their stress response may help d
Externí odkaz:
https://doaj.org/article/5ff99a956aef4b80a9f931d76725ad60
Autor:
Carline Chaves-Almagro, Johanna Auriau, Alizée Dortignac, Pascal Clerc, Hubert Lulka, Simon Deleruyelle, Fabrice Projetti, Jessica Nakhlé, Audrey Frances, Judit Berta, Véronique Gigoux, Daniel Fourmy, Marlène Dufresne, Anne Gomez-Brouchet, Julie Guillermet-Guibert, Pierre Cordelier, Bernard Knibiehler, Ralf Jockers, Philippe Valet, Yves Audigier, Bernard Masri
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10600 (2022)
Despite decades of effort in understanding pancreatic ductal adenocarcinoma (PDAC), there is still a lack of innovative targeted therapies for this devastating disease. Herein, we report the expression of apelin and its receptor, APJ, in human pancre
Externí odkaz:
https://doaj.org/article/6514b8b037c048ae9efac2ad0527e39d
Autor:
Elodie Urlacher, Laurent Soustelle, Marie-Laure Parmentier, Heleen Verlinden, Marie-Julie Gherardi, Daniel Fourmy, Alison R Mercer, Jean-Marc Devaud, Isabelle Massou
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146248 (2016)
Sequencing of the honeybee genome revealed many neuropeptides and putative neuropeptide receptors, yet functional characterization of these peptidic systems is scarce. In this study, we focus on allatostatins, which were first identified as inhibitor
Externí odkaz:
https://doaj.org/article/43732571ca474245aec9e4d860fee3db
Publikováno v:
Nanomaterials, Vol 8, Iss 7, p 468 (2018)
Doxorubicin is a cytotoxic drug used for the treatment of many cancer types. However, its significant dose-related adverse effects including cardiotoxicity may hamper its efficiency. Moreover, the multidrug resistance that appears during treatments l
Externí odkaz:
https://doaj.org/article/8fb0327444e3416a832ddef3b736c98a
Autor:
Véronique Gigoux, Nicolas Hallali, Pascal Clerc, Daniel Fourmy, Arnaud Hillion, Yoann Lalatonne, Nizar Serhan, Joana C. Antunes, Sara Lopez, Laurence Motte, Julian Carrey
Publikováno v:
Nanoscale advances. 4(2)
The destruction of cells using the mechanical activation of magnetic nanoparticles with low-frequency magnetic fields constitutes a recent and interesting approach in cancer therapy. Here, we showed that superparamagnetic iron oxide nanoparticles as
Publikováno v:
Reubi, J C, Fourmy, D, Cordomi, A, Tikhonova, I G & Gigoux, V 2019, ' GIP receptor : Expression in neuroendocrine tumours, internalization, signalling from endosomes and structure-function relationship studies ', Peptides, pp. 170229 . https://doi.org/10.1016/j.peptides.2019.170229
GIP is well known as a peptide regulating metabolic functions. In this review paper, we summarize a series of data on GIP receptor (GIPR). First, expression study of GIPR in human neuroendocrine tumours showed a very high incidence (nearly 100%) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9391b2c076bd2e61ec8e9d6f7a0fc0
Publikováno v:
Biologie Aujourd'hui. 212:13-19
Les récepteurs couplés aux protéines G (RCPG) représentent la plus grande famille de récepteurs membranaires. Classiquement, il était admis que la signalisation des RCPG, résultant de leur couplage aux protéines G, provenait exclusivement du
Publikováno v:
Cordomí, A, Fourmy, D & Tikhonova, I G 2016, ' Gut hormone GPCRs: structure, function, drug discovery ', Current Opinion in Pharmacology, vol. 31, pp. 63-67 . https://doi.org/10.1016/j.coph.2016.09.001
Crystallization and determination of the high resolution three-dimensional structure of the β2-adrenergic receptor in 2007 was followed by structure elucidation of a number of other receptors, including those for neurotensin and glucagon. These majo
Publikováno v:
Mol Pharmacol
Many physiologic processes are controlled through the activation of G protein-coupled receptors (GPCRs) by regulatory peptides, making peptide GPCRs particularly useful targets for major human diseases such as diabetes and cancer. Peptide GPCRs are a
Autor:
Eduardo Mayol, Daniel Fourmy, Leonardo Pardo, José Carlos Gómez-Tamayo, Mireia Olivella, Arnau Cordomí
Publikováno v:
Protein Science. 25:1517-1524
The interactions of Met and Cys with other amino acid side chains have received little attention, in contrast to aromatic-aromatic, aromatic-aliphatic or/and aliphatic-aliphatic interactions. Precisely, these are the only amino acids that contain a s