Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Daniel Forler"'
Publikováno v:
Chemical Science. 6:237-245
Acivicin is a natural product with diverse biological activities. Several decades ago its clinical application in cancer treatment was explored but failed due to unacceptable toxicity. The causes behind the desired and undesired biological effects ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80568e893ae504b85bc7893df1a7704
https://doi.org/10.1039/c4sc02339k
https://doi.org/10.1039/c4sc02339k
Publikováno v:
Nature Biotechnology. 21:89-92
The ensemble of expressed proteins in a given cell is organized in multiprotein complexes1,2. The identification of the individual components of these complexes is essential for their functional characterization. The introduction of the 'tandem affin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cb09ad0cd431ceea9344354793c164e
https://doi.org/10.1038/nbt773
https://doi.org/10.1038/nbt773
Publikováno v:
EMBO reports. 2:1119-1124
The proteins Mago and Y14 are evolutionarily conserved binding partners. Y14 is a component of the exon–exon junction complex (EJC), deposited by the spliceosome upstream of messenger RNA (mRNA) exon–exon junctions. The EJC is implicated in post-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f1be806b874884b9331fec0f2da2d6
https://doi.org/10.1093/embo-reports/kve245
https://doi.org/10.1093/embo-reports/kve245
Autor:
Ricarda Niggeweg, Gwénaël Rabut, Andrea Herold, Francesca D. Ciccarelli, Jan Ellenberg, Peer Bork, Elisa Izaurralde, Thomas Köcher, Daniel Forler
Publikováno v:
Molecular and cellular biology. 24(3)
Metazoan NXF1-p15 heterodimers promote the nuclear export of bulk mRNA across nuclear pore complexes (NPCs). In vitro, NXF1-p15 forms a stable complex with the nucleoporin RanBP2/Nup358, a component of the cytoplasmic filaments of the NPC, suggesting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb596de80c3a0b0005ca1d4e24db0cd4
https://pubmed.ncbi.nlm.nih.gov/14729961
https://pubmed.ncbi.nlm.nih.gov/14729961
Autor:
Lars Linden, Khusru Asadullah, Sabine Wittemer-Rump, Matthew Nelson, Ulf Forssmann, Thomas Krahn, Joseph R. Couto, Joerg Willuda, Claudia Schneider, Yifei Zhu, Daniel Forler, Zhiming Liao, Alton Hiscox, Robert Pytela, Ricarda Finnern
Publikováno v:
Cancer Research. 74:2836-2836
C4.4a (LYPD3), a GPI-anchored cell surface protein, has been identified previously as a cancer- and metastasis-associated cell surface protein. It is expressed in a variety of cancer indications and, particularly, in the squamous cell subtype of non-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::331febcf2f8f3599685f78bfef8c8449
https://doi.org/10.1158/1538-7445.am2014-2836
https://doi.org/10.1158/1538-7445.am2014-2836