Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniel Flicker"'
Publikováno v:
Cell Reports, Vol 27, Iss 5, Pp 1364-1375.e5 (2019)
Summary: The mitochondrial calcium uniporter has been proposed to coordinate the organelle’s energetics with calcium signaling. Uniporter current has previously been reported to be extremely high in brown adipose tissue (BAT), yet it remains unknow
Externí odkaz:
https://doaj.org/article/fd04d9da610c4a0f974cd7a87b412fc3
Autor:
Rebecca Li, Benjamin A. Olenchock, Shinichi Kai, Tomoaki Ida, Yumiko Yamazaki, Hozumi Motohashi, Naohiro Mori, Masanobu Morita, Xinggui Shen, Daniel Flicker, Christopher G. Kevil, Annabelle Batten, Dmitriy N. Atochin, Lisa Traeger, Benjamin Corman, Yusuke Miyazaki, Eizo Marutani, Fumiaki Nagashima, Motohiro Nishida, Kenjiro Hanaoka, Robert M. H. Grange, Aurora Magliocca, Takaaki Akaike, Daniel Bloch, Tetsuro Matsunaga, Takamitsu Ikeda, Shuichi Hirai, Tomohiro Tanaka, Akito Nakagawa, Fumito Ichinose, Ming Xian, Allyson G. Hindle, Hideshi Ihara
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications
The mammalian brain is highly vulnerable to oxygen deprivation, yet the mechanism underlying the brain’s sensitivity to hypoxia is incompletely understood. Hypoxia induces accumulation of hydrogen sulfide, a gas that inhibits mitochondrial respirat
Autor:
Katherine M. Nautiyal, Jeremy Veenstra-VanderWeele, Holly Moore, Christoph Kellendonk, Muhammad Omar Chohan, Gregg D. Stanwood, Isaac D. Zike, Kenji F. Tanaka, Michael Bubser, Daniel Flicker, Jared M. Kopelman, Carrie K. Jones, Susanne E. Ahmari, Emily N. Krasnow
Publikováno v:
Proceedings of the National Academy of Sciences. 114:5719-5724
Obsessive-compulsive disorder (OCD) is a chronic, disabling condition with inadequate treatment options that leave most patients with substantial residual symptoms. Structural, neurochemical, and behavioral findings point to a significant role for ba
Autor:
William Pierce, Fei Ji, Daniel Flicker, Joseph Avruch, Nicholas E. Houstis, Laura Regué, Liliana Minichiello, Ning Dai, Jeffrey J. Widrick, Dana Kramer, Teekhon Davidoff
Insulin-like growth factor 2 (IGF2) mRNA binding protein 2 (IMP2) was selectively deleted from adult mouse muscle; two phenotypes were observed: decreased accrual of skeletal muscle mass after weaning and reduced wheel-running activity but normal for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dceb3935b3836849712c1606e998eae
https://ora.ox.ac.uk/objects/uuid:5a865c30-504c-438e-a2e0-82a27c2613f7
https://ora.ox.ac.uk/objects/uuid:5a865c30-504c-438e-a2e0-82a27c2613f7
Autor:
Gregory C. Campanello, Vamsi K. Mootha, Cheng Luo, Ruma Banerjee, Zenon Grabarek, Hongying Shen, Junchi Hu, Daniel Flicker
Publikováno v:
Cell. 171:771-782.e11
CLYBL encodes a ubiquitously expressed mitochondrial enzyme, conserved across all vertebrates, whose cellular activity and pathway assignment are unknown. Its homozygous loss is tolerated in seemingly healthy individuals, with reduced circulating B12
Publikováno v:
Europe PubMed Central
RNA interference is a natural gene expression silencing system that appears throughout the tree of life. As the list of cellular processes linked to RNAi grows, so does the demand for tools to accurately measure RNAi dynamics in living cells. We engi