Zobrazeno 1 - 10
of 602
pro vyhledávání: '"Daniel Fink"'
Autor:
Waleed Kian, Belal Krayim, Betsy Giles, Nasim A. Elkiaan, Amjad Idris, Daniel Fink, Nir Peled, Laila C. Roisman
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundOver the past decade, progress in the diagnosis and treatment of Non-Small Cell Lung Cancer (NSCLC) has led to the identification of many targeted mutations. This has enhanced PFS and OS in both advanced and early-stage NSCLC. The current s
Externí odkaz:
https://doaj.org/article/d63d6b099fac4d74a9cb497e63f4c04c
Autor:
Daniel Fink, Alison Johnston, Matt Strimas‐Mackey, Tom Auer, Wesley M. Hochachka, Shawn Ligocki, Lauren Oldham Jaromczyk, Orin Robinson, Chris Wood, Steve Kelling, Amanda D. Rodewald
Publikováno v:
Methods in Ecology and Evolution, Vol 14, Iss 9, Pp 2435-2448 (2023)
Abstract Citizen and community science datasets are typically collected using flexible protocols. These protocols enable large volumes of data to be collected globally every year; however, the consequence is that these protocols typically lack the st
Externí odkaz:
https://doaj.org/article/c6df2c7058494513bc0c4f090c551ba5
Publikováno v:
Methods in Ecology and Evolution, Vol 14, Iss 3, Pp 923-938 (2023)
Abstract Large‐scale monitoring of seasonal animal movement is integral to science, conservation and outreach. However, gathering representative movement data across entire species ranges is frequently intractable. Citizen science databases collect
Externí odkaz:
https://doaj.org/article/9d9f602b26264134aaff6cb99542679f
Autor:
Mara De Marco Zompit, Mònica Torres Esteban, Clémence Mooser, Salomé Adam, Silvia Emma Rossi, Alain Jeanrenaud, Pia-Amata Leimbacher, Daniel Fink, Ann-Marie K. Shorrocks, Andrew N. Blackford, Daniel Durocher, Manuel Stucki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
In this work, CIP2A is discovered as a TOPBP1-interacting protein that regulates TOPBP1 localization specifically in mitosis. Cells lacking CIP2A display increased radio-sensitivity, micronuclei formation and chromosomal instability.
Externí odkaz:
https://doaj.org/article/6bb76f98748d456bb28f51f91a387637
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 32, Iss , Pp 100893- (2022)
Infantile onset Pompe disease (IOPD) is a rare devastating disease that presents in early infancy with rapidly progressive hypertrophic cardiomyopathy, severe generalized myopathy and death within the first year of life. The emergence of enzyme repla
Externí odkaz:
https://doaj.org/article/a9f869d8a0744b229b6f4b410c6c5558
Clustering community science data to infer songbird migratory connectivity in the Western Hemisphere
Publikováno v:
Ecosphere, Vol 13, Iss 4, Pp n/a-n/a (2022)
Abstract Migratory connectivity describes the spatial linkage among migrating individuals through time. Accounting for it is necessary for full annual cycle conservation planning, to avoid uneven protection leading to overall population declines. How
Externí odkaz:
https://doaj.org/article/863db9447ed9459395a7fec9d8f8f267
Autor:
Clémence Mooser, Ioanna-Eleni Symeonidou, Pia-Amata Leimbacher, Alison Ribeiro, Ann-Marie K. Shorrocks, Stephanie Jungmichel, Sara C. Larsen, Katja Knechtle, Arti Jasrotia, Diana Zurbriggen, Alain Jeanrenaud, Colin Leikauf, Daniel Fink, Michael L. Nielsen, Andrew N. Blackford, Manuel Stucki
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
DNA double-strand breaks in ribosomal DNA repeats is associated with repression of ribosomal RNA synthesis. Here the authors reveal a cooperation between TOPBP1 and Treacle in the signaling cascade that triggers transcriptional inhibition and nucleol
Externí odkaz:
https://doaj.org/article/1e40f7a690df46ba8c9721ca498fe614
Publikováno v:
Ecosphere, Vol 13, Iss 3, Pp n/a-n/a (2022)
Abstract Artificial light at night (ALAN) is adversely affecting natural systems worldwide, including the disorienting influence of ALAN on nocturnally migrating birds. Understanding how ALAN trends are developing across species' seasonal distributio
Externí odkaz:
https://doaj.org/article/ac8065e2193f422aa7b4e8c1eaf3a4b3
Autor:
Richard Schuster, Scott Wilson, Amanda D. Rodewald, Peter Arcese, Daniel Fink, Tom Auer, Joseph. R. Bennett
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Conservation decisions to protect land used by migratory birds rely on understanding species’ dynamic habitat associations. Here the authors identify conservation scenarios needed to maintain >30% of the abundances of 117 migratory birds across the
Externí odkaz:
https://doaj.org/article/3b8ff8363edd435781b93fed0265e770
Publikováno v:
Reproductive Biology and Endocrinology, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background Matrix metalloproteinases (MMPs), especially the gelatinases MMP-2 and MMP-9, play a crucial role in the pathogenesis of endometriosis by enabling invasion. Doxycycline is a well-tolerated antibiotic and a potent MMP-inhibitor in
Externí odkaz:
https://doaj.org/article/7fb468786f1e482688ca6bc1b47c50ba