Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Daniel F. Zegarra-Ruiz"'
Autor:
Andrea A. Hill, Myunghoo Kim, Daniel F. Zegarra-Ruiz, Lin-Chun Chang, Kendra Norwood, Adrien Assié, Wan-Jung H. Wu, Michael C. Renfroe, Hyo Wong Song, Angela M. Major, Buck S. Samuel, Joseph M. Hyser, Randy S. Longman, Gretchen E. Diehl
Publikováno v:
JCI Insight, Vol 8, Iss 3 (2023)
Chronic exposure to high-fat diets (HFD) worsens intestinal disease pathology, but acute effects of HFD in tissue damage remain unclear. Here, we used short-term HFD feeding in a model of intestinal injury and found sustained damage with increased ce
Externí odkaz:
https://doaj.org/article/4dbaf7f237bf47bcb811593b4ac7bcb2
Autor:
Wan-Jung H. Wu, Myunghoo Kim, Lin-Chun Chang, Adrien Assie, Fatima B. Saldana-Morales, Daniel F. Zegarra-Ruiz, Kendra Norwood, Buck S. Samuel, Gretchen E. Diehl
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
The gut microbiota is essential for maintenance and repair of the intestinal epithelial barrier. As shifts in both intestinal epithelial barrier function and microbiota composition are found in inflammatory bowel disease patients, it is critical to u
Externí odkaz:
https://doaj.org/article/d1986751dd1b4d0e82580752b75daa21
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Autoimmune diseases and chronic inflammatory disorders are characterized by dysregulated immune responses resulting in excessive and uncontrolled tissue inflammation. Multiple factors including genetic variation, environmental stimuli, and infection
Externí odkaz:
https://doaj.org/article/a894412908a44bf2b4e48a9ccd4a53e0
Autor:
Daniel F. Zegarra Ruiz, Dasom V. Kim, Kendra Norwood, Fatima B. Saldana-Morales, Myunghoo Kim, Charles Ng, Ryann Callaghan, Maisha Uddin, Lin-Chun Chang, Randy S. Longman, Gretchen E. Diehl
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Inflammatory bowel disease (IBD) is a chronic life-long inflammatory disease affecting almost 2 million Americans. Although new biologic therapies have been developed, the standard medical treatment fails to selectively control the dysregulated immun
Externí odkaz:
https://doaj.org/article/076f987d17534bbeadec6dc34ad59701
Autor:
Andrea A. Hill, Myunghoo Kim, Daniel F. Zegarra-Ruiz, Lin-Chun Chang, Kendra Norwood, Adrien Assié, Wan-Jung H. Wu, Michael C. Renfroe, Hyo Wong Song, Angela M. Major, Buck S. Samuel, Joseph M. Hyser, Randy S. Longman, Gretchen E. Diehl
Publikováno v:
JCI insight.
Chronic exposure to high-fat diets (HFD) worsens intestinal disease pathology, but acute effects of HFD in tissue damage remain unclear. Here, we used short-term HFD feeding in a model of intestinal injury and found sustained damage with increased ce
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Autoimmune diseases and chronic inflammatory disorders are characterized by dysregulated immune responses resulting in excessive and uncontrolled tissue inflammation. Multiple factors including genetic variation, environmental stimuli, and infection
Autor:
Gretchen E. Diehl, Randy S. Longman, Andrea A. Hill, Wan Jung H. Wu, Matthew L. Bettini, Fatima B. Saldana-Morales, Shubhabrata Majumdar, Rickesha Bell, Dasom Kim, Takeshi Egawa, Daniel F. Zegarra-Ruiz, Myunghoo Kim, June L. Round, Stephanie Orozco, Kendra Norwood
Publikováno v:
Nature. 594(7863)
Humans and their microbiota have coevolved a mutually beneficial relationship in which the human host provides a hospitable environment for the microorganisms and the microbiota provides many advantages for the host, including nutritional benefits an
Publikováno v:
Trends in Immunology. 40:177-179
In a recent study, Harrison et al. (Science 2019;363;eaat6280) report that RORγt-expressing skin commensal-specific T cells rapidly respond to tissue wounding by producing type 2 T helper cell (Th2) cytokines in mice. The cells constitutively coexpr
Autor:
Gretchen E. Diehl, Hyo Won Song, Myunghoo Kim, Daniel F. Zegarra-Ruiz, Angela Major, Andrea A. Hill, Kendra Norwood, Michael C. Renfroe, Wan-Jung Wu
Defective tissue repair is a hallmark of many inflammatory disorders including, inflammatory bowel disease (IBD). While it is clear that high fat diets (HFD) can exacerbate inflammatory disease by increasing inflammation, the direct effect of lipids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a119a9e2d139f7de5260dcd9760a234c
https://doi.org/10.1101/790220
https://doi.org/10.1101/790220
Autor:
Martina Lubrano Di Ricco, William Ruff, Rebecca L. Fine, Teri M. Greiling, Carina Dehner, Alonso J. Iñiguez, John Sterpka, Silvio M. Vieira, Derek L. Mubiru, Daniel F. Zegarra-Ruiz, Asmaa El Beidaq, Martin A. Kriegel
Publikováno v:
Cell hostmicrobe. 25(1)
Summary Western lifestyle is linked to autoimmune and metabolic diseases, driven by changes in diet and gut microbiota composition. Using Toll-like receptor 7 (TLR7)-dependent mouse models of systemic lupus erythematosus (SLE), we dissect dietary eff