Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Daniel F. Lyons"'
Autor:
David M. Jameson, Robert Wright, Sara E. Wingate, Randy M. Wadkins, Samantha M. Reilly, John J. Correia, Daniel F. Lyons
Publikováno v:
Biophysical Journal. 107(7):1703-1711
The four-stranded i-motif (iM) conformation of cytosine-rich DNA has importance to a wide variety of biochemical systems that range from their use in nanomaterials to potential roles in oncogene regulation. The iM structure is formed at slightly acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd790ea72681325aceeee0ca6f1fbe5
Autor:
Andrew C. Holley, Keith H. Parsons, Wenming Wan, Daniel F. Lyons, G. Reid Bishop, John J. Correia, Faqing Huang, Charles L. McCormick
Publikováno v:
Polym. Chem.. 5:6967-6976
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6efa8cc888ca919788d783d6b581a8a
https://doi.org/10.1039/c4py00940a
https://doi.org/10.1039/c4py00940a
Autor:
Edwin A. Lewis, Drazen Raucher, Daniel F. Lyons, Wolfgang Kramer, Vu H. Le, Gene L. Bidwell, John J. Correia
Publikováno v:
Biophysical Journal. 104:2009-2021
The therapeutic potential of elastin-like polypeptide (ELP) conjugated to therapeutic compounds is currently being investigated as an approach to target drugs to solid tumors. ELPs are hydrophobic polymers that are soluble at low temperatures and coo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6984dccd2d791427487ae0f4cf3cabc9
https://doi.org/10.1016/j.bpj.2013.03.040
https://doi.org/10.1016/j.bpj.2013.03.040
Autor:
Julia T. Philip, Emily O. Alberico, Ryan J. Murphy, Daniel F. Lyons, Aranda R. Duan, Holly V. Goodson, John J. Correia
Publikováno v:
Cytoskeleton. 70:317-327
EB1 is a highly conserved microtubule (MT) plus end tracking protein (+TIP) involved in regulating MT dynamics, but the mechanisms of its effects on MT polymerization remain undefined. Resolving this question requires understanding how EB1 interacts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a8312f6c748aca4c7c7e4c28614abfd
https://doi.org/10.1002/cm.21108
https://doi.org/10.1002/cm.21108
Publikováno v:
Analytical Ultracentrifugation ISBN: 9784431559832
The development of the fluorescence detection system (Aviv-FDS) for the AUC allows a single fluorescently labeled species to be quantitatively characterized against a highly concentrated and heterogeneous background. During our use of the FDS to char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33c6c77ea7dde6cb9e3894b1617e157e
https://doi.org/10.1007/978-4-431-55985-6_24
https://doi.org/10.1007/978-4-431-55985-6_24
Autor:
Daniel F. Lyons, Sarah E. Morgan, Lea C. Paslay, Amit Kumar, Vijayaraghavan Rangachari, John J. Correia
Publikováno v:
Journal of Biological Chemistry. 287:21253-21264
Aggregates of amyloid-β (Aβ) peptides have been implicated in the etiology of Alzheimer disease. Among the different forms of Aβ aggregates, low molecular weight species ranging between ~2- and 50-mers, also called "soluble oligomers," have emerge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6367981298f156086ab796cee1569e21
https://doi.org/10.1074/jbc.m112.355156
https://doi.org/10.1074/jbc.m112.355156
Autor:
Edwin A. Lewis, Drazen Raucher, Daniel F. Lyons, Wolfgang Kramer, Vu H. Le, Gene L. Bidwell, John J. Correia
Publikováno v:
Biochemistry
Elastin-like polypeptides (ELPs) are large, nonpolar polypeptides under investigation as components of a novel drug delivery system. ELPs are soluble at low temperatures, but they desolvate and aggregate above a transition temperature (TT). This aggr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3052e4c21e694e00e5243619ca8915b6
https://pubmed.ncbi.nlm.nih.gov/24450599
https://pubmed.ncbi.nlm.nih.gov/24450599
Publikováno v:
Analytical biochemistry. 437(2)
Sedimentation velocity analytical ultracentrifugation is a classical biophysical technique that is commonly used to analyze the size, shape, and interactions of biological macromolecules in solution. Fluorescence detection provides enhanced sensitivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa6743f667ff0e4d33820dca03e5e5c
https://pubmed.ncbi.nlm.nih.gov/23499970
https://pubmed.ncbi.nlm.nih.gov/23499970
Autor:
Emily O, Alberico, Daniel F, Lyons, Ryan J, Murphy, Julia T, Philip, Aranda R, Duan, John J, Correia, Holly V, Goodson
Publikováno v:
Cytoskeleton (Hoboken, N.J.). 70(6)
EB1 is a highly conserved microtubule (MT) plus end tracking protein (+TIP) involved in regulating MT dynamics, but the mechanisms of its effects on MT polymerization remain undefined. Resolving this question requires understanding how EB1 interacts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45878326de117d7bebbac761b6576032
https://pubmed.ncbi.nlm.nih.gov/23864329
https://pubmed.ncbi.nlm.nih.gov/23864329
Publikováno v:
Biophysical Journal. 100(3)
Perhaps the largest impediment in cancer therapies has been the inability to effectively target systemically delivered therapeutics to cancerous cells. A recent and novel approach to this problem has been to chemically conjugate the therapeutic to an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04087d67da70860a54659ec3febf0715