Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Daniel F. Heiter"'
Autor:
Thomas Lutz, Honorata Czapinska, Alexey Fomenkov, Vladimir Potapov, Daniel F. Heiter, Bo Cao, Peter Dedon, Matthias Bochtler, Shuang-yong Xu
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Modification dependent restriction endonucleases (MDREs) restrict modified DNA, typically with limited sequence specificity (∼2–4 bp). Here, we focus on MDREs that have an SRA and/or SBD (sulfur binding domain) fused to an HNH endonuclease domain
Externí odkaz:
https://doaj.org/article/4b58b90d7c874a5e895ee148c19d4cf9
Autor:
Betty W Shen, Lindsey Doyle, Phil Bradley, Daniel F Heiter, Keith D Lunnen, Geoffrey G Wilson, Barry L Stoddard
Publikováno v:
Nucleic Acids Research
BbvCI, a Type IIT restriction endonuclease, recognizes and cleaves the seven base pair sequence 5′-CCTCAGC-3′, generating 3-base, 5′-overhangs. BbvCI is composed of two protein subunits, each containing one catalytic site. Either site can be in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d224c210ec2e3de26b61700fb124ec2e
https://doi.org/10.1093/nar/gky1059
https://doi.org/10.1093/nar/gky1059
Publikováno v:
Nucleic Acids Research
R.SwaI, a Type IIP restriction endonuclease, recognizes a palindromic eight base pair (bp) symmetric sequence, 5΄-ATTTAAAT-3΄, and cleaves that target at its center to generate blunt-ended DNA fragments. Here, we report three crystal structures of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf8fdaae4dcb1ae56b32a252dee5795
http://europepmc.org/articles/PMC5415892
http://europepmc.org/articles/PMC5415892
Publikováno v:
Encuentro, Iss 93, Pp 01-30 (2012)
Since their discovery in the nineteen-seventies, a collection of simple enzymes termed Type II restriction endonucleases, made by microbes to ward off viral infections, have transformed molecular biology, spawned the multi-billion dollar Biotechnolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1868cebd2b5971622ccb06e90c59ea20
https://doi.org/10.5377/encuentro.v0i93.909
https://doi.org/10.5377/encuentro.v0i93.909
Publikováno v:
Nucleic Acids Research
Homing endonuclease are proteins that drive the dominant, non-Mendelian inheritance of their own reading frames by catalyzing a double-strand break (DSB) at specific DNA target sites in a recipient genome (1). The DSB is repaired via homologous recom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6091afae9243cb84dd837a3c3da834
http://europepmc.org/articles/PMC3239194
http://europepmc.org/articles/PMC3239194
Autor:
Siu-Hong Chan, Betty W. Shen, Daniel F. Heiter, Richard D. Morgan, Hua Wang, Shuang-yong Xu, Geoffrey G. Wilson, Barry L. Stoddard
Publikováno v:
Structure. 18:734-743
The crystal structure of the rare-cutting HNH restriction endonuclease PacI in complex with its eight-base-pair target recognition sequence 5'-TTAATTAA-3' has been determined to 1.9 A resolution. The enzyme forms an extended homodimer, with each subu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b91670827f4840f2cc7b259d58a16c7
https://doi.org/10.1016/j.str.2010.03.009
https://doi.org/10.1016/j.str.2010.03.009
Autor:
Lucia Greenough, Laurie S. Moran, Joan E. Brooks, Emma Jean Hess, Barton E. Slatko, Daniel F. Heiter, Jack S. Benner, Brian P. Anton
Publikováno v:
Gene. 187:19-27
BglII, a type II restriction–modification (R–M) system from Bacillus globigii, recognizes the sequence 5′-AGATCT-3′. The system has been cloned into E. coli in multiple steps: first the methyltransferase (MTase) gene, bglIIM, was cloned from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c257981ac134bf5ee26a56b25a60260d
https://doi.org/10.1016/s0378-1119(96)00638-5
https://doi.org/10.1016/s0378-1119(96)00638-5
Autor:
Geoffrey G. Wilson, Daniel F. Heiter, Richard J. Roberts, Jonathan O'Driscoll, Gerald F. Fitzgerald, Douwe van Sinderen
Publikováno v:
BMC Microbiology, Vol 6, Iss 1, p 40 (2006)
BMC Microbiology
BMC Microbiology
Background Restriction/modification systems provide the dual function of protecting host DNA against restriction by methylation of appropriate bases within their recognition sequences, and restriction of foreign invading un-methylated DNA, such as pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d37d9801ab094b3e4ddd7d354026428
http://www.biomedcentral.com/1471-2180/6/40
http://www.biomedcentral.com/1471-2180/6/40
Publikováno v:
Journal of molecular biology. 348(3)
The restriction enzyme R.BbvCI cleaves duplex DNA within a seven base-pair asymmetric recognition sequence, thus: CCTCAGC/GCTGAGG-->CC--TCAGC/GC--TGAGG. We show that R.BbvCI comprises two different subunits, R(1) and R(2); that each subunit contains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4204566ab6df196846f17448c679b8
https://pubmed.ncbi.nlm.nih.gov/15826660
https://pubmed.ncbi.nlm.nih.gov/15826660
Autor:
Donald O. Nwankwo, Daniel F. Heiter, Laura A. Sznyter, Tina Jager-Quinton, Barton E. Slatko, Karen R. Silber, Jack S. Benner, Geoffrey G. Wilson, Laurie S. Moran, Joan E. Brooks
Publikováno v:
Nucleic Acids Research. 17:979-997
BamHI, a Type II restriction modification system from Bacillus amyloliquefaciensH recognizes the sequence GGATCC. The methylase and endonuclease genes have been cloned into E. coli in separate steps; the clone is able to restrict unmodified phage. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4ff2b1529cc7385b06c4de7c010098
https://doi.org/10.1093/nar/17.3.979
https://doi.org/10.1093/nar/17.3.979