Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Daniel F. Bogenhagen"'
Publikováno v:
Cell Reports, Vol 22, Iss 7, Pp 1935-1944 (2018)
Summary: Mammalian mtDNA encodes only 13 proteins, all essential components of respiratory complexes, synthesized by mitochondrial ribosomes. Mitoribosomes contain greatly truncated RNAs transcribed from mtDNA, including a structural tRNA in place of
Externí odkaz:
https://doaj.org/article/fe375e22102e4dc89b0a026b82facfa2
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0249047 (2021)
Mitochondria are commonly viewed as highly elongated organelles with regularly spaced mtDNA genomes organized as compact nucleoids that generate the local transcripts essential for production of mitochondrial ribosomes and key components of the respi
Externí odkaz:
https://doaj.org/article/1d66dc4bfabb479694533af623a72a83
Autor:
Nehaben A. Gujarati, Yiqing Guo, Alexandra R. Leonardo, John Cijiang He, Ilse Daehn, Monica P. Revelo, Bismark O. Frimpong, Jessica M Vasquez, Sandeep K. Mallipattu, Elbek Fozilov, Daniel F. Bogenhagen
Publikováno v:
Diabetes
Increased oxidative stress in glomerular endothelial cells (GEnCs) contributes to early diabetic kidney disease (DKD). While mitochondrial respiratory complex IV activity is reduced in DKD, it remains unclear whether this is a driver or a consequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be11227b66c59d0ba4771f6df57b27f2
https://doi.org/10.2337/db21-0316
https://doi.org/10.2337/db21-0316
Publikováno v:
Am J Physiol Renal Physiol
Mitochondria play a complex role in maintaining cellular function including ATP generation, generation of biosynthetic precursors for macromolecules, maintenance of redox homeostasis, and metabolic waste management. Although the contribution of mitoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788d74afa82d914037a9bad94aff7c65
https://doi.org/10.1152/ajprenal.00393.2020
https://doi.org/10.1152/ajprenal.00393.2020
Autor:
Luigi Ferrucci, Katrina N Estep, Thomas J. Butler, Robert W. Maul, David Schlessinger, Andrew R. Wood, Marcus A. Tuke, Joshua A. Sommers, Thomas A. Guilliam, Francesco Cucca, Daniel F. Bogenhagen, Alicia K. Byrd, Aidan J. Doherty, Stefania Bandinelli, Robert M. Brosh, Sanjay Kumar Bharti, Elena Yakubovskaya, Miguel Garcia-Diaz, Ann Zenobia Moore, Jun Ding, Kevin D. Raney
Publikováno v:
Hum Mol Genet
As the powerhouses of the eukaryotic cell, mitochondria must maintain their genomes which encode proteins essential for energy production. Mitochondria are characterized by guanine-rich DNA sequences that spontaneously form unusual three-dimensional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afb2d119be5d18078f77c07bad4b4f8
https://doi.org/10.1093/hmg/ddaa043
https://doi.org/10.1093/hmg/ddaa043
Autor:
Daniel F. Bogenhagen, John D. Haley
Mammalian mitochondria assemble four complexes of the respiratory chain (RCI, RCIII, RCIV, and RCV) by combining 13 polypeptides synthesized within mitochondria on mitochondrial ribosomes (mitoribosomes) with over 70 polypeptides encoded in nuclear D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e815735471c604a3a6db61160fc45734
https://europepmc.org/articles/PMC7049976/
https://europepmc.org/articles/PMC7049976/
Autor:
Mridu Gulati, Wajahat Z. Mehal, Jaden Faunce, Caitlin Brandsdorfer, Jose D. Herazo-Maya, Varvara Kirillov, Jonathan Puchalski, Daniel F Bogenhagen, Christina Blaul, Erica L. Herzog, Anjelica L. Gonzalez, Glenda Trujillo, Raimund I. Herzog, Kathleen O. Lindell, Martin D. Slade, Huanxing Sun, Changwan Ryu, Kevin F. Gibson, Naftali Kaminski, Yonglin Chen, Julia Winkler, Argyrios Tzouvelekis, Danielle Antin-Ozerkis, Tony Woolard, Hongyi Pan, Carol Feghali-Bostwick, Charles S. Dela Cruz, Awo Osafo-Addo
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 196:1571-1581
Idiopathic pulmonary fibrosis (IPF) involves the accumulation of α-smooth muscle actin-expressing myofibroblasts arising from interactions with soluble mediators such as transforming growth factor-β1 (TGF-β1) and mechanical influences such as loca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f90a6beadf9cbd20558ef60e6ea3f3
https://doi.org/10.1164/rccm.201612-2480oc
https://doi.org/10.1164/rccm.201612-2480oc
Publikováno v:
Advances in experimental medicine and biology. 1140
The global measurement of assembly and turnover of protein containing complexes within cells has advanced with the development of pulse stable isotope labelled amino acid approaches. Stable isotope labeling with amino acids in cell culture (SILAC) al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d485b01bbb33050e7d0c5929cfe8412a
https://pubmed.ncbi.nlm.nih.gov/31347072
https://pubmed.ncbi.nlm.nih.gov/31347072
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030159498
The global measurement of assembly and turnover of protein containing complexes within cells has advanced with the development of pulse stable isotope labelled amino acid approaches. Stable isotope labeling with amino acids in cell culture (SILAC) al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29627d1bc13f411019083782a02ee08d
https://doi.org/10.1007/978-3-030-15950-4_34
https://doi.org/10.1007/978-3-030-15950-4_34
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 3, p e0249047 (2021)
PLoS ONE, Vol 16, Iss 3, p e0249047 (2021)
Mitochondria are commonly viewed as highly elongated organelles with regularly spaced mtDNA genomes organized as compact nucleoids that generate the local transcripts essential for production of mitochondrial ribosomes and key components of the respi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec443ff169476582224f6a99ac56e959
https://doi.org/10.1371/journal.pone.0249047
https://doi.org/10.1371/journal.pone.0249047