Výsledky vyhledávání - "Daniel F. Bennett"

Akademický článek

A neurodevelopmental disorder caused by a dysfunctional CACNA1A allele

Autor: Audra A. Kramer, Daniel F. Bennett, Kristin W. Barañano, Roger A. Bannister

Publikováno v: eNeurologicalSci, Vol 31, Iss , Pp 100456- (2023)

P/Q-type Ca2+ flux into nerve terminals via CaV2.1 channels is essential for neurotransmitter release at neuromuscular junctions and nearly all central synapses. Mutations in CACNA1A, the gene encoding CaV2.1, cause a spectrum of pediatric neurologic

Externí odkaz: https://doaj.org/article/62fc694941264769aaef24c81178310f

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Akademický článek

Complex effects on CaV2.1 channel gating caused by a CACNA1A variant associated with a severe neurodevelopmental disorder

Autor: Benjamin J. Grosso, Audra A. Kramer, Sidharth Tyagi, Daniel F. Bennett, Cynthia J. Tifft, Precilla D’Souza, Michael F. Wangler, Ellen F. Macnamara, Ulises Meza, Roger A. Bannister

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)

Abstract P/Q-type Ca2+ currents mediated by CaV2.1 channels are essential for active neurotransmitter release at neuromuscular junctions and many central synapses. Mutations in CACNA1A, the gene encoding the principal CaV2.1 α1A subunit, cause a bro

Externí odkaz: https://doaj.org/article/dcb8f1d708834618b720d6b36eaa5a9b

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Voltage sensor movements of CaV1.1 during an action potential in skeletal muscle fibers

Autor: Martin F. Schneider, Hugo Bibollet, Minerva Contreras, Quinton Banks, Roger A. Bannister, Erick O. Hernández-Ochoa, Daniel F Bennett

Publikováno v: Journal of General Physiology. 154

In excitation–contraction coupling (ECC), when the skeletal muscle action potential (AP) propagates into the transverse tubules, it modifies the conformational state of the voltage-gated calcium channels (CaV1.1). CaV1.1 serves as the voltage senso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3fb3bb37a3e60f3624a12ce1701a073e
https://doi.org/10.1085/jgp.2021ecc43

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Voltage sensor movements of Ca V 1.1 during an action potential in skeletal muscle fibers

Autor: Roger A. Bannister, Daniel F Bennett, Martin F. Schneider, Minerva Contreras, Erick O. Hernández-Ochoa, Hugo Bibollet, Quinton Banks

Publikováno v: Proceedings of the National Academy of Sciences. 118

The skeletal muscle L-type Ca2+ channel (CaV1.1) works primarily as a voltage sensor for skeletal muscle action potential (AP)-evoked Ca2+ release. CaV1.1 contains four distinct voltage-sensing domains (VSDs), yet the contribution of each VSD to AP-e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55ca093dd74873132822e0cdaf46be7b
https://doi.org/10.1073/pnas.2026116118

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Voltage sensor movements of Ca

Autor: Quinton, Banks, Hugo, Bibollet, Minerva, Contreras, Daniel F, Bennett, Roger A, Bannister, Martin F, Schneider, Erick O, Hernández-Ochoa

Publikováno v: Proc Natl Acad Sci U S A

The skeletal muscle L-type Ca(2+) channel (Ca(V)1.1) works primarily as a voltage sensor for skeletal muscle action potential (AP)-evoked Ca(2+) release. Ca(V)1.1 contains four distinct voltage-sensing domains (VSDs), yet the contribution of each VSD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c52e41f57ba1c7c97cea7b50f72ae1e0
https://pubmed.ncbi.nlm.nih.gov/34583989

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