Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Daniel F. Alonso"'
Autor:
Luisina M. Solernó, Natasha T. Sobol, María F. Gottardo, Carla S. Capobianco, Maximiliano R. Ferrero, Liliana Vásquez, Daniel F. Alonso, Juan Garona
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Osteosarcoma is still associated with limited response to standard-of-care therapy and alarmingly elevated mortality rates, especially in low- and middle-income countries. Despite multiple efforts to repurpose β-blocker propranolol in oncol
Externí odkaz:
https://doaj.org/article/76e6670f3c4042928bf7821dcad04983
Autor:
Georgina A. Cardama, Paula L. Bucci, Jesús S. Lemos, Candela Llavona, Micaela A. Benavente, Eva Hellmén, María Laura Fara, Eduardo Medrano, Eduardo Spitzer, Ignacio A. Demarco, Patricia Sabella, Juan Garona, Daniel F. Alonso
Publikováno v:
Animals, Vol 13, Iss 15, p 2507 (2023)
Canine mammary carcinomas (CMC) are associated with major aggressive clinical behavior and high mortality. The current standard of care is based on surgical resection, without an established effective treatment scheme, highlighting the urgent need to
Externí odkaz:
https://doaj.org/article/9e0424f45d844cd3943bd3a9a65bc0bd
Autor:
Alejandro Krolewiecki, Adrián Lifschitz, Matías Moragas, Marina Travacio, Ricardo Valentini, Daniel F. Alonso, Rubén Solari, Marcelo A. Tinelli, Rubén O. Cimino, Luis Álvarez, Pedro E. Fleitas, Laura Ceballos, Marcelo Golemba, Florencia Fernández, Diego Fernández de Oliveira, German Astudillo, Inés Baeck, Javier Farina, Georgina A. Cardama, Andrea Mangano, Eduardo Spitzer, Silvia Gold, Carlos Lanusse
Publikováno v:
EClinicalMedicine, Vol 39, Iss , Pp 101119- (2021)
Externí odkaz:
https://doaj.org/article/c1764cf40f3f4805a93edf70da908719
Autor:
Ayelen Toro, Sofia Lage-Vickers, Juan Bizzotto, Felipe Vilicich, Agustina Sabater, Gaston Pascual, Sabrina Ledesma-Bazan, Pablo Sanchis, Maria Sol Ruiz, Ana Paula Arevalo, Jorge L. Porfido, Mercedes Abbate, Rocio Seniuk, Estefania Labanca, Nicolas Anselmino, Nora M. Navone, Daniel F. Alonso, Elba Vazquez, Martina Crispo, Javier Cotignola, Geraldine Gueron
Publikováno v:
Viruses, Vol 14, Iss 10, p 2180 (2022)
Interferon gamma (IFN-γ) may be potential adjuvant immunotherapy for COVID-19 patients. In this work, we assessed gene expression profiles associated with the IFN-γ pathway in response to SARS-CoV-2 infection. Employing a case-control study from SA
Externí odkaz:
https://doaj.org/article/a1111bd98958406886f051fb8a95053c
Preclinical Efficacy and Toxicology Evaluation of RAC1 Inhibitor 1A-116 in Human Glioblastoma Models
Autor:
Georgina A. Cardama, Julian Maggio, Lucas Valdez Capuccino, Nazareno Gonzalez, Valentina Matiller, Hugo H. Ortega, German R. Perez, Ignacio A. Demarco, Eduardo Spitzer, Daniel E. Gomez, Pablo Lorenzano Menna, Daniel F. Alonso
Publikováno v:
Cancers, Vol 14, Iss 19, p 4810 (2022)
Malignant gliomas are the most common primary central nervous system tumor in adults. Despite current therapeutics, these tumors are associated with poor prognosis and a median survival of 16 to 19 months. This highlights the need for innovative trea
Externí odkaz:
https://doaj.org/article/7dd353e1f55b48e59a63af8bb499eeb8
Autor:
Alejandro Krolewiecki, Adrián Lifschitz, Matías Moragas, Marina Travacio, Ricardo Valentini, Daniel F. Alonso, Rubén Solari, Marcelo A. Tinelli, Rubén O. Cimino, Luis Álvarez, Pedro E. Fleitas, Laura Ceballos, Marcelo Golemba, Florencia Fernández, Diego Fernández de Oliveira, German Astudillo, Inés Baeck, Javier Farina, Georgina A. Cardama, Andrea Mangano, Eduardo Spitzer, Silvia Gold, Carlos Lanusse
Publikováno v:
EClinicalMedicine, Vol 37, Iss , Pp 100959- (2021)
Background: There are limited antiviral options for the treatment of patients with COVID-19. Ivermectin (IVM), a macrocyclic lactone with a wide anti-parasitary spectrum, has shown potent activity against SARS-CoV-2 in vitro. This study aimed at asse
Externí odkaz:
https://doaj.org/article/42dbd47b55024b43afc025c81b6e6a77
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/25680b2745cc413ab43b472cdfe7f5ab
Autor:
Ana María eVázquez, Ana María eHernández, Amparo eMacías, Enrique eMontero, Daniel E. Gómez, Daniel F. Alonso, Mariano R. Gabri, Roberto eGómez
Publikováno v:
Frontiers in Oncology, Vol 2 (2012)
Neu-glycolyl (NeuGc) containing gangliosides are attractive targets for immunotherapy with anti-idiotype mAbs, because these glycolipids are not normal components of the cytoplasmatic membrane in humans, but their expression has been demonstrated in
Externí odkaz:
https://doaj.org/article/be5a1449a72741c89ed57c0bd33b1e70
Autor:
Alejandra M. Scursoni, Laura Galluzzo, Sandra Camarero, Jessica Lopez, Fabiana Lubieniecki, Claudia Sampor, Valeria I. Segatori, Mariano R. Gabri, Daniel F. Alonso, Guillermo Chantada, María Teresa G. de Dávila
Publikováno v:
Clinical and Developmental Immunology, Vol 2011 (2011)
The N-glycolylated ganglioside NeuGc-GM3 has been described in solid tumors such as breast carcinoma, nonsmall cell lung cancer, and melanoma, but is usually not detected in normal human cells. Our aim was to evaluate the presence of NeuGc-GM3 in ped
Externí odkaz:
https://doaj.org/article/419bb88c1b654ec0941352d0469db38a
Autor:
Luis E. Fernandez, Mariano R. Gabri, Marcelo D. Guthmann, Roberto E. Gomez, Silvia Gold, Leonardo Fainboim, Daniel E. Gomez, Daniel F. Alonso
Publikováno v:
Clinical and Developmental Immunology, Vol 2010 (2010)
Active specific immunotherapy is a promising field in cancer research. N-glycolyl (NGc) gangliosides, and particularly NGcGM3, have received attention as a privileged target for cancer therapy. Many clinical trials have been performed with the anti-N
Externí odkaz:
https://doaj.org/article/b3127abec810436d86ce18398d85e757