Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Daniel F, Cimino"'
Autor:
Wadih Arap, Martin J. Edelman, Andrew Bradbury, Daniel F. Cimino, Maria I. Nunez, Ming D. Qian, Julianna K. Edwards, Ignacio I. Wistuba, Andrey S. Dobroff, Ximing Tang, Fortunato Ferrara, Roy R. Lobb, Waun Ki Hong, Richard L. Sidman, Fernanda I. Staquicini, Renata Pasqualini, Diane D. Liu, J. Jack Lee, Patrick J. Kelly, Ahmad Salameh, Benjamin J. Moeller
Publikováno v:
The Journal of Biological Chemistry
Background: EphA5 is a functional target in lung cancer, the most common cause of tumor-related death in mankind. Results: EphA5 regulates cell cycle checkpoints and DNA damage repair induced by ionizing radiation. Conclusion: EphA5 is a novel regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a7fe5f0c4b412748e1e3a3398f937c
https://doi.org/10.1074/jbc.m114.630525
https://doi.org/10.1074/jbc.m114.630525
Publikováno v:
The Journal of Immunology. 176:5418-5425
Adaptation, defined as the diminution of receptor signaling in the presence of continued or repeated stimulation, is critical to cellular function. G protein-coupled receptors (GPCRs) undergo multiple adaptive processes, including desensitization and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153a02850bc3ce97744dcbb196124570
https://doi.org/10.4049/jimmunol.176.9.5418
https://doi.org/10.4049/jimmunol.176.9.5418
Autor:
Larry A. Sklar, Eric R. Prossnitz, Chetana M. Revankar, Daniel F. Cimino, Jeffrey B. Arterburn
Publikováno v:
Science. 307:1625-1630
The steroid hormone estrogen regulates many functionally unrelated processes in numerous tissues. Although it is traditionally thought to control transcriptional activation through the classical nuclear estrogen receptors, it also initiates many rapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c8afcc8502458252c9310ec3e7b317
https://doi.org/10.1126/science.1106943
https://doi.org/10.1126/science.1106943
Autor:
Daniel F. Cimino, Tione Buranda, Mei Xue, Teresa A. Bennett, Charlotte M. Vines, Eric R. Prossnitz
Publikováno v:
Journal of Biological Chemistry. 279:45175-45184
In response to ligand binding, G protein-coupled receptors undergo phosphorylation and activate cellular internalization machinery. An important component of this process is the concentration of receptors into clusters on the plasma membrane. Aside f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538c486e904051bb24fddd6a8ef2b601
https://doi.org/10.1074/jbc.m407053200
https://doi.org/10.1074/jbc.m407053200
Publikováno v:
Journal of Biological Chemistry. 279:24578-24584
G protein (heterotrimeric guanine nucleotide-binding protein)-coupled receptors (GPCRs) activate numerous cellular signals through the combined actions of G proteins, GPCR kinases, and arrestins. Although arrestins have traditionally been thought of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb69af295201ab4690320824a77d4949
https://doi.org/10.1074/jbc.m402121200
https://doi.org/10.1074/jbc.m402121200
Autor:
Daniel F. Cimino, Susan M. Scott
Publikováno v:
Journal of Perinatology. 24:429-434
OBJECTIVE: The relationship between the concentrations of cortisol and T4 with outcome in the preterm infants has not been well studied. STUDY DESIGN: Mean cortisol (days 2, 4, and 6) and T4 values were correlated to gestational age, illness, and out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645f9182921cedca98fd9ce225a76926
https://doi.org/10.1038/sj.jp.7211112
https://doi.org/10.1038/sj.jp.7211112
Autor:
Eric R. Prossnitz, Sean M. Biggs, Wei-Jen Tang, Anna Waller, Larry A. Sklar, Richard R. Neubig, Qing Guo, Daniel F. Cimino, Peter C. Simons, Terry D. Foutz
Publikováno v:
Journal of Biological Chemistry. 279:13514-13521
We developed a novel and generalized approach to investigate G protein-coupled receptor molecular assemblies. We solubilized a fusion protein consisting of the β2-adrenergic receptor and green fluorescent protein (GFP) for bead-based flow cytometric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca42c8ef4dc42046ab590c63d4efcfb9
https://doi.org/10.1074/jbc.m310306200
https://doi.org/10.1074/jbc.m310306200
Autor:
Eric R. Prossnitz, Diane C. Maestas, Robert J. Lefkowitz, Leah L. LaRusch, Charlotte M. Vines, Trudy A. Kohout, Chetana M. Revankar, Daniel F. Cimino
Publikováno v:
Journal of Biological Chemistry. 278:41581-41584
Arrestins mediate phosphorylation-dependent desensitization, internalization, and initiation of signaling cascades for the majority of G protein-coupled receptors (GPCRs). Many GPCRs undergo agonist-mediated internalization through arrestin-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c63b0041e514bc363e241de8b4906c
https://doi.org/10.1074/jbc.c300291200
https://doi.org/10.1074/jbc.c300291200
Autor:
Vsevolod V. Gurevich, Daniel F. Cimino, Mei Shi, Diane C. Maestas, Teresa A. Bennett, Terry D. Foutz, Larry A. Sklar, Eric R. Prossnitz
Publikováno v:
Biochemistry. 42:7283-7293
G protein-coupled receptors (GPCRs) must constantly compete for interactions with G proteins, kinases, and arrestins. To evaluate the interactions of these proteins with GPCRs in greater detail, we generated a fusion protein between the N-formyl pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39da04104d3935570d095eaa74771614
https://doi.org/10.1021/bi0341657
https://doi.org/10.1021/bi0341657
Autor:
Tione Buranda, Peter C. Simons, Daniel F. Cimino, Daniel Sivalingam, Larry A. Sklar, Angela Wandinger-Ness, Jacob O. Agola
Publikováno v:
Methods in Molecular Biology ISBN: 9781493925681
Rab7 facilitates vesicular transport and delivery from early endosomes to late endosomes as well as from late endosomes to lysosomes. The role of Rab7 in vesicular transport is dependent on its interactions with effector proteins, among them Rab-inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ff58e700e01db72d08187ab381a16b
https://europepmc.org/articles/PMC6033261/
https://europepmc.org/articles/PMC6033261/
