Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Daniel Essigke"'
Autor:
Daniel Essigke, Bernhard N. Bohnert, Andrea Janessa, Matthias Wörn, Kingsley Omage, Hubert Kalbacher, Andreas L. Birkenfeld, Thomas H. Bugge, Roman Szabo, Ferruh Artunc
Publikováno v:
Pflugers Arch. 474, 613-624 (2022)
Experimental nephrotic syndrome leads to activation of the epithelial sodium channel (ENaC) by proteolysis and promotes renal sodium retention. The membrane-anchored serine protease prostasin (CAP1/PRSS8) is expressed in the distal nephron and partic
Autor:
Travis Nemkov, Jonathan M. Beirne, Irene Gonzalez-Menendez, Lina Schaefer, Leticia Quintanilla-Martinez, Lingsi Kong, Mengyun Xiao, Daniel Essigke, Bernhard N. Bohnert, Rosi Bissinger, Anja Schork, Martin Schaller, M. Zaher Kalo, Birgit Fehrenbacher, Matthias Wörn, Kingsley Omage, Marijke Grau, Tamam Bakchoul, Angelo D'Alessandro, Achal Dhariwal, Florian Grahammer, Syed M. Qadri, Andreas L. Birkenfeld, Thomas Dietz, Ferruh Artunc
Publikováno v:
Kidney International. 100:1227-1239
Anemia is a common complication of chronic kidney disease, affecting the quality of life of patients. Among various factors, such as iron and erythropoietin deficiency, reduced red blood cell (RBC) lifespan has been implicated in the pathogenesis of
Autor:
Bernhard N, Bohnert, Daniel, Essigke, Andrea, Janessa, Jonas C, Schneider, Matthias, Wörn, M Zaher, Kalo, Mengyun, Xiao, Lingsi, Kong, Kingsley, Omage, Jörg, Hennenlotter, Bastian, Amend, Andreas L, Birkenfeld, Ferruh, Artunc
Publikováno v:
American journal of physiology. Renal physiology. 321(4)
Proteolytic activation of the renal epithelial Na
Autor:
Daniel Essigke, Kerstin Amann, Thomas H. Bugge, Ferruh Artunc, Roman Szabo, Matthias Wörn, Andreas L. Birkenfeld, Bernhard N. Bohnert, Mengyun Xiao, Christoph Korbmacher, Christoph Daniel, Alexandr V. Ilyaskin
Publikováno v:
Acta Physiol. 232:e13640 (2021)
Acta Physiol (Oxf)
Acta Physiol (Oxf)
Aim The serine protease prostasin (Prss8) is expressed in the distal tubule and stimulates proteolytic activation of the epithelial sodium channel (ENaC) in co-expression experiments in vitro. The aim of this study was to explore the role of prostasi
Autor:
Ferruh Artunc, Lingsi Kong, Bernhard N. Bohnert, Andreas L. Birkenfeld, Matthias Wörn, Andrea Janessa, Daniel Essigke, Mengyun Xiao, Joerg Hennenlotter, Jonas C Schneider, Bastian Amend, M. Zaher Kalo, Kingsley Omage
Publikováno v:
Am. J. Physiol.-Renal Physiol. 321, F480-F493 (2021)
Proteolytic activation of the renal epithelial sodium channel ENaC involves cleavage events in its α- and γ-subunits and is thought to mediate sodium retention in nephrotic syndrome (NS). However, detection of proteolytically processed ENaC in kidn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11cd4867f8627bc1f2bcd602d63427bd
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62888
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62888
Autor:
Ferruh Artunc, Bernhard N. Bohnert, Jonas C. Schneider, Tobias Staudner, Florian Sure, Alexandr V. Ilyaskin, Matthias Wörn, Daniel Essigke, Andrea Janessa, Nis V. Nielsen, Andreas L. Birkenfeld, Michael Etscheid, Silke Haerteis, Christoph Korbmacher, Sandip M. Kanse
Publikováno v:
Pflügers Archiv, 2022(474):217-229
Pflugers Archiv
Pflugers Arch. 474, 217-229 (2022)
Pflugers Archiv
Pflugers Arch. 474, 217-229 (2022)
Proteolytic activation of the epithelial sodium channel (ENaC) by aberrantly filtered serine proteases is thought to contribute to renal sodium retention in nephrotic syndrome. However, the identity of the responsible proteases remains elusive. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45650f55637d2b812841cb6d95a7372
https://repository.publisso.de/resource/frl:6431670
https://repository.publisso.de/resource/frl:6431670
Autor:
Christoph Daniel, Ferruh Artunc, Mengyun Xiao, Daniel Essigke, Bernhard N. Bohnert, Matthias Wörn, Kerstin Amann, Oliver Kretz, Andrea Janessa, Andreas L. Birkenfeld, Hande Aypek, Edward F. Plow, Ute Aukschun, Tobias B. Huber, Florian Grahammer
Publikováno v:
Acta Physiol (Oxf)
Acta Physiol. 231:e13512 (2020)
Acta Physiol. 231:e13512 (2020)
AIM: Sodium retention is the hallmark of nephrotic syndrome (NS) and mediated by the proteolytic activation of the epithelial sodium channel (ENaC) by aberrantly filtered serine proteases. Plasmin is highly abundant in nephrotic urine and has been pr
Autor:
Ferruh Artunc, Sophie Daiminger, Tobias Staudner, Daniel Essigke, Matthias Wörn, Christoph Korbmacher, Florian Sure, Firas Batbouta, Bernhard N. Bohnert, Sandip M. Kanse, Andrea Janessa, Jonas C Schneider, Alexandr V. Ilyaskin, Silke Haerteis
Publikováno v:
Acta Physiol. 227:e13286 (2019)
Aim In nephrotic syndrome, aberrantly filtered plasminogen (plg) is converted to active plasmin by tubular urokinase-type plasminogen activator (uPA) and thought to lead to sodium retention by proteolytic activation of the epithelial sodium channel (
Autor:
Alvin H. Schmaier, Daniel Essigke, Regina Nacken, Ferruh Artunc, Andrea Janessa, Anja Schork, Hans-Ulrich Häring, Marko Bertog, Edward P. Feener, Mengyun Xiao, Thomas Dörffel, Matthias Wörn, Christoph Korbmacher, Silke Haerteis, Bernhard N. Bohnert
Publikováno v:
Acta Physiol. 224:e13060 (2018)
AIM Recent work has demonstrated that activation of the epithelial sodium channel (ENaC) by aberrantly filtered serine proteases causes sodium retention in nephrotic syndrome. The aim of this study was to elucidate a potential role of plasma kallikre