Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Daniel E.B. Swinson"'
Autor:
M.D. Peake, Jane L. Atkins, David A. Waller, Daniel E.B. Swinson, Antonio E. Martin-Ucar, Kenneth J. O'Byrne
Publikováno v:
Lung Cancer. 46:227-232
We aimed to evaluate the effect of the appointment of a dedicated specialist thoracic surgeon on surgical practice for lung cancer previously served by cardio-thoracic surgeons. Outcomes were compared for the 240 patients undergoing surgical resectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d4194ba1e04e6fcbc4520165715f57
https://doi.org/10.1016/j.lungcan.2004.03.010
https://doi.org/10.1016/j.lungcan.2004.03.010
Publikováno v:
British Journal of Cancer
The epidermal growth factor receptor (EGFR) is commonly expressed in non-small-cell lung cancer (NSCLC) and promotes a host of mechanisms involved in tumorigenesis. However, EGFR expression does not reliably predict prognosis or response to EGFR-targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269e764da20e6e180c851ec10097b01d
https://doi.org/10.1038/sj.bjc.6602149
https://doi.org/10.1038/sj.bjc.6602149
Autor:
Kenneth J. O'Byrne, Daniel E.B. Swinson, Adrian L. Harris, J. Louise Jones, Donna Richardson, Giles Cox
Publikováno v:
International Journal of Cancer. 111:43-50
Hypoxia-inducible factor (HIF)-1 alpha is the regulatory subunit of HIF-1 that is stabilized under hypoxic conditions. Under different circumstances, HIF-1 alpha may promote both tumorigenesis and apoptosis. There is conflicting data on the importanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b9a6abf8f2280d4f473bf0bb4eec2c
https://doi.org/10.1002/ijc.20052
https://doi.org/10.1002/ijc.20052
Autor:
John G. Edwards, Daniel E.B. Swinson, J. Louise Jones, David A. Waller, Kenneth J. O'Byrne, Salli Muller
Publikováno v:
Chest. 124:1916-1923
Objectives: Malignant mesothelioma (MM) is a fatal tumor of increasing incidence related to asbestos exposure. Microscopic tumor necrosis (TN) is a poor prognostic factor in solid tumors, but it has not been characterized in MM. We wished to evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6b7c98de43fadf8e0eab56759e7221
https://doi.org/10.1378/chest.124.5.1916
https://doi.org/10.1378/chest.124.5.1916
Autor:
J. Louise Jones, Nick Taub, Daniel E.B. Swinson, Kenneth J. O'Byrne, Helen Turley, Adrian L. Harris, Donna Richardson, Jaromir Pastorek, Charles C. Wykoff
Publikováno v:
Journal of Clinical Oncology. 21:473-482
Purpose: To evaluate carbonic anhydrase (CA) IX as a surrogate marker of hypoxia and investigate the prognostic significance of different patterns of expression in non–small-cell lung cancer (NSCLC). Methods: Standard immunohistochemical techniques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6decc191e90857644034e8a80284aa1
https://doi.org/10.1200/jco.2003.11.132
https://doi.org/10.1200/jco.2003.11.132
Autor:
Al Harris, Gerard Cox, K C Gatter, A Andi, Kenneth J. O'Byrne, Daniel E.B. Swinson, J Lolljee, Alexandra Giatromanolaki, J. L. Jones, M I Koukourakis, David A. Waller, D Richardson, John G. Edwards
Publikováno v:
Scopus-Elsevier
Non-small cell lung cancer is the most common cause of cancer-related death in North America and Europe. Despite improvements in the diagnosis and treatment of the disease the prognosis remains poor, the overall 5-year survival being 4–14%. An incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a26f156190f73b5ae6538f074728ae
https://doi.org/10.1016/s0169-5002(01)00352-x
https://doi.org/10.1016/s0169-5002(01)00352-x
Autor:
John G. Edwards, Duncan Stewart, Catherine M. Richardson, Daniel E.B. Swinson, Dipika Patel, J. Louise Jones, Amit Shah, Kenneth J. O'Byrne, Donna Richardson, William A. Swain
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(8)
Akt, a Serine/Threonine protein kinase, mediates growth factor–associated cell survival. Constitutive activation of Akt (phosphorylated Akt, P-Akt) has been observed in several human cancers, including lung cancer and may be associated with poor pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf8c6ed037e455db96512bb9e528f8c
https://pubmed.ncbi.nlm.nih.gov/15837744
https://pubmed.ncbi.nlm.nih.gov/15837744
Autor:
D. Richardson, C. M. Richardson, Daniel E.B. Swinson, Kenneth J. O'Byrne, W. A. Swain, Gerard Cox
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 48(1)
Both cyclooxygenase (COX)-2 and epidermal growth factor receptor (EGFR) are thought to play important roles in the pathogenesis of non-small cell lung cancer (NSCLC). A number of in vitro studies have postulated a link between EGFR activation and sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5973e800f9106245ffee92c2fa8fa9c1
https://pubmed.ncbi.nlm.nih.gov/15777970
https://pubmed.ncbi.nlm.nih.gov/15777970