Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Daniel E. Mitchell"'
Autor:
Jan-Moritz Sutter, Daniel E. Mitchell, Marcel Schmidt, Michail N. Isupov, Jennifer A. Littlechild, Peter Schönheit
Publikováno v:
Frontiers in Catalysis, Vol 2 (2022)
A branched chain aminotransferase from Thermoproteus tenax has been identified, cloned, over-expressed and biochemically characterised. A molecular modelling approach has been used to predict the 3D structure allowing its comparison with other relate
Externí odkaz:
https://doaj.org/article/3134fe04d7bc4c0ca2eda41e791427f3
Autor:
José F. Gutierrez-Marcos, Alice E. R. Fayter, Muhammad Hasan, Daniel E. Mitchell, Matthew I. Gibson, Robert C. Deller
Publikováno v:
Materials Horizons
Antifreeze-protein mimic polymers are shown to enable solvent-free storage of important proteins for therapy and biotechnology by modulating ice growth.
Proteins are ubiquitous in molecular biotechnology, biotechnology and as therapeutics, but t
Proteins are ubiquitous in molecular biotechnology, biotechnology and as therapeutics, but t
Publikováno v:
Biomaterials science. 2(12)
Antifreeze (glyco) proteins (AF(G)Ps) from the blood of polar fish species are extremely potent ice recrystallization inhibitors (IRI), but are difficult to synthesise or extract from natural sources. Despite this challenge, materials which display I
Autor:
Alasdair T. M. Hubbard, Collette S. Guy, Matthew I. Gibson, Daniel J. Phillips, Elizabeth Fullam, Ian Hands-Portman, James Harrison, Daniel E. Mitchell, Sarah-Jane Richards, Esther Tichauer
Publikováno v:
Biomacromolecules
Antimicrobial resistance is a global healthcare problem with a dwindling arsenal of usable drugs. Tuberculosis, caused by Mycobacterium tuberculosis, requires long-term combination therapy and multi- and totally drug resistant strains have emerged. T
Autor:
Rosa Lanzetta, Ettore Novellino, Matthew I. Gibson, Ermenegilda Parrilli, Filomena Sannino, Angela Casillo, Daniel E. Mitchell, Gennaro Marino, Michelangelo Parrilli, Maria Luisa Tutino, Antonio Randazzo, Sandro Cosconati, Maria Michela Corsaro
Publikováno v:
Carbohydrate Polymers
Microrganisms from sea ice, glacial and subglacial environments are currently under investigation due to their relevant ecological functions in these habitats, and to their potential biotechnological applications. The cold-adapted Colwellia psychrery
Autor:
Angela Casillo, Jonas Ståhle, Ermenegilda Parrilli, Filomena Sannino, Daniel E. Mitchell, Giuseppina Pieretti, Matthew I. Gibson, Gennaro Marino, Rosa Lanzetta, Michelangelo Parrilli, Göran Widmalm, Maria L. Tutino, Maria M. Corsaro
Publikováno v:
Antonie van Leeuwenhoek
Colwellia psychrerythraea strain 34H, a Gram-negative bacterium isolated from Arctic marine sediments, is considered a model to study the adaptation to cold environments. Recently, we demonstrated that C. psychrerythraea 34H produces two different ex
Autor:
Ermenegilda Parrilli, Angela Casillo, Maria Michela Corsaro, Jonas Ståhle, Daniel E. Mitchell, Rosa Lanzetta, Michelangelo Parrilli, Filomena Sannino, Göran Widmalm, Gennaro Marino, Maria Luisa Tutino, Giuseppina Pieretti, Matthew I. Gibson
Colwellia psychrerythraea strain 34H, a Gram-negative bacterium isolated from Arctic marine sediments, is considered a model to study the adaptation to cold environments. Recently, we demonstrated that C. psychrerythraea 34H produces two different ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0b69b954327c91e26e0d92fe2cc2d8
http://hdl.handle.net/11588/663533
http://hdl.handle.net/11588/663533
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie International Edition
Angewandte Chemie International Edition
The first fully synthetic polymer‐based approach for red‐blood‐cell cryopreservation without the need for any (toxic) organic solvents is reported. Highly hydroxylated block copolymer worms are shown to be a suitable replacement for hydroxyethy
Publikováno v:
Chemical Communications (Cambridge, England)
A structurally simple synthetic polymer based on alternating charged side chains is designed and synthesised to mimic antifreeze proteins. The polymer is found to enhance the cryopreservation of red blood cells.
Antifreeze (glyco) proteins AF(G)
Antifreeze (glyco) proteins AF(G)
Publikováno v:
Scientific Reports
Antifreeze (glyco)proteins are found in polar fish species and act to slow the rate of growth of ice crystals; a property known as ice recrystallization inhibition. The ability to slow ice growth is of huge technological importance especially in the