Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Daniel E. Libutti"'
Autor:
Tanvi Sharma, Mariana Gerschenson, Mitchell E. Geffner, Jennifer Jao, Denise L. Jacobson, Jonathan S Russell, Daniel E. Libutti, Russell B. Van Dyke, Greg S. Gojanovich
Publikováno v:
AIDS Res Hum Retroviruses
Mitochondrial dysfunction (MD) is linked to cardiometabolic complications, such as obesity and insulin resistance (IR), the frequencies of which are higher in adults living with HIV infection and receiving combination antiretroviral therapies (ARV).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c49dbf4f1baa9fe935cebc065fc4bb
https://doi.org/10.1089/aid.2020.0067
https://doi.org/10.1089/aid.2020.0067
Autor:
Cecilia M. Shikuma, Daniel E. Libutti, Dominic C. Chow, Mariana Gerschenson, Cris Milne, Greg S. Gojanovich
Publikováno v:
AIDS Res Hum Retroviruses
Lipoatrophy, or fat wasting, remains a syndrome plaguing HIV(+) patients receiving antiretroviral (ARV) therapy. Both HIV infection per se and certain ARV are associated with lowered adipose tissue mitochondrial deoxyribonucleic acid (mtDNA) and mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb3c1a884f714326c442dd7b508da8a
https://doi.org/10.1089/aid.2019.0121
https://doi.org/10.1089/aid.2019.0121
Autor:
Cecilia M. Shikuma, Maegen Walker, Talia M. Nir, Neda Jahanshad, Robert H. Paul, Lindsay B Kohorn, Mariana Gerschenson, Daniel E. Libutti, Kalpana J. Kallianpur, Louie Mar A Gangcuangco, Paul M. Thompson
Publikováno v:
AIDS Res Hum Retroviruses
Few studies have examined systemic mitochondrial function in conjunction with brain imaging in human immunodeficiency virus (HIV) disease. Oxidative phosphorylation enzyme protein levels of peripheral blood mononuclear cells were measured in associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97412a13af004525b25498caa3df1659
https://europepmc.org/articles/PMC6944134/
https://europepmc.org/articles/PMC6944134/
Autor:
Todd T. Brown, John R. Koethe, David C. Samuels, Daniel E. Libutti, Benjamin S. Ramsey, Todd Hulgan, Paul E. Sax, Eric S. Daar, Grace A. McComsey, Mariana Gerschenson
OBJECTIVE Some antiretroviral therapy (ART) and HIV itself confer metabolic risk, perhaps through altered mitochondrial function and adipokines. In AIDS Clinical Trials Group study A5224s, adipose mitochondrial DNA (mtDNA) levels decreased on ART, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8c9367c0048914e5e0f54bc01e7aaa
https://europepmc.org/articles/PMC6375746/
https://europepmc.org/articles/PMC6375746/
Autor:
Kristen E. Stevenson, Lewis B. Silverman, Donna Neuberg, Lynn Anderson, Lynda M. Vrooman, Vivian I. Franco, Tracie L. Miller, Stephen E. Sallan, Daniel E. Libutti, Mariana Gerschenson, Steven E. Lipshultz
Publikováno v:
Cancer. 122:946-953
BACKGROUND Impaired cardiac function in doxorubicin-treated childhood cancer survivors is partly mediated by the disruption of mitochondrial energy production. Doxorubicin intercalates into mitochondrial DNA (mtDNA) and disrupts genes encoding for po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a61c4d9fab5dd47e289a34a7aef15ad
https://doi.org/10.1002/cncr.29872
https://doi.org/10.1002/cncr.29872
Autor:
Todd, Hulgan, Rebecca T, Levinson, Mariana, Gerschenson, Nittaya, Phanuphak, Jintanat, Ananworanich, Nipat, Teeratakulpisarm, Tanate, Jadwattanakul, Daniel E, LiButti, Heidi, Fink, Justin C, McArthur, Gigi J, Ebenezer, Peter, Hauer, Deborah, Murdock, Cecilia M, Shikuma, David C, Samuels, Praphan, Phanuphak
Publikováno v:
AIDS. 28:1625-1633
We explored associations between mitochondrial DNA (mtDNA) haplogroups, epidermal nerve fiber density (ENFD), and HIV-associated sensory neuropathy (HIV-SN) in a randomized trial of Thai patients initiating antiretroviral therapy (ART).The South East
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef452f96af9cee286682c89f527e79c
https://doi.org/10.1097/qad.0000000000000297
https://doi.org/10.1097/qad.0000000000000297
Autor:
Chin Yuan Liang, Cecilia M. Shikuma, Deirdre A. Killebrew, Louie Mar A Gangcuangco, Lishomwa C. Ndhlovu, Dominic C. Chow, Mariana Gerschenson, Cris Milne, Bruce Shiramizu, Jason D. Barbour, Daniel E. Libutti, Beau K. Nakamoto
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 65:151-159
OBJECTIVE To assess the role of HIV and monocytes/macrophages in adipose tissue dysregulation. METHODS Cross-sectional study in 5 groups: HIV seronegative, HIV+ antiretroviral therapy (ART)-naive, HIV+ nonlipoatrophic on zidovudine- and/or stavudine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3eecae815f6f0ec8b2851cc17d40a5e
https://doi.org/10.1097/01.qai.0000435599.27727.6c
https://doi.org/10.1097/01.qai.0000435599.27727.6c
Autor:
David Rowe, Norma Storer, Daniel E. Libutti, Mariana Gerschenson, Grace A. McComsey, Danielle Harrill, Julia Choi, MaryAnn O'Riordan
Publikováno v:
Antiviral Therapy. 17:347-353
Background Lipoatrophy modestly improves when the thymidine analogue nucleoside reverse transcriptase inhibitor (tNRTI) is removed. In vitro, uridine (Nucleo-maxX®; Pharma Nord, Vojens, Denmark) reversed tNRTI mitochondrial toxicity. Methods All pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f02d92186ecbf5b55ff126ea8dca7e1
https://doi.org/10.3851/imp1928
https://doi.org/10.3851/imp1928
Autor:
Mariana Gerschenson, Michelle Chung, Daniel E. Libutti, Salvatore DiMauro, Ali Naini, Susan B. Brogly, Julia Choi, Paige L. Williams, Russell B. Van Dyke
Publikováno v:
AIDS Research and Human Retroviruses. 27:777-783
Transplacental nucleoside analogue exposure can affect infant mitochondrial DNA (mtDNA). We evaluated mitochondria in peripheral blood mononuclear cells of children with and without clinical signs of mitochondrial dysfunction (MD) and antiretroviral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865430c00eecfd6daf25e269b3455b6c
https://doi.org/10.1089/aid.2010.0204
https://doi.org/10.1089/aid.2010.0204
Autor:
MaryAnn O'Riordan, Jessica M. Shelton, Jason C. Ganz, Grace A. McComsey, Daniel E. Libutti, Norma Storer, John J. Jasper, Danielle Harrill, Mariana Gerschenson
Publikováno v:
Antiviral Therapy. 13:715-722
Background The aim of this study was to assess the effect of antiretroviral therapy (ART) versus HIV on mitochondria in fat. Methods Subcutaneous fat was collected from 45 HIV-infected patients on ART with lipoatrophy, 11 HIV-infected ART-naive patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9ed5babb7bfc447eaf40883c06c56d8
https://doi.org/10.1177/135965350801300511
https://doi.org/10.1177/135965350801300511