Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Daniel E. Huddleston"'
Autor:
Jonathan E. Elliott, Miranda M. Lim, Allison T. Keil, Ronald B. Postuma, Amelie Pelletier, Jean‐François Gagnon, Erik K. St. Louis, Leah K. Forsberg, Julie A. Fields, Daniel E. Huddleston, Donald L. Bliwise, Alon Y. Avidan, Michael J. Howell, Carlos H. Schenck, Jennifer McLeland, Susan R. Criswell, Aleksandar Videnovic, Emmanuel H. During, Mitchell G. Miglis, David R. Shprecher, Joyce K. Lee‐Iannotti, Bradley F. Boeve, Yo‐El S. Ju, the North American Prodromal Synucleinopathy (NAPS) Consortium
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 4, Pp 520-535 (2023)
Abstract Objective Rapid eye movement (REM) sleep behavior disorder (RBD) is widely considered a prodromal synucleinopathy, as most with RBD develop overt synucleinopathy within ~10 years. Accordingly, RBD offers an opportunity to test potential trea
Externí odkaz:
https://doaj.org/article/31d9613c029c455b8349abb5094f206a
Publikováno v:
PLoS ONE, Vol 18, Iss 4 (2023)
Patients with Parkinson’s disease undergo a loss of melanized neurons in substantia nigra pars compacta and locus coeruleus. Very few studies have assessed substantia nigra pars compacta and locus coeruleus pathology in Parkinson’s disease simult
Externí odkaz:
https://doaj.org/article/b0fe8ac1b7824b79b237239adec866e0
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
IntroductionStriatal dopamine transporter (DAT) imaging using 123I-ioflupane single photon positron emitted computed tomography (SPECT) (DaTScan, GE) identifies 5−20% of newly diagnosed Parkinson’s disease (PD) subjects enrolling in clinical stud
Externí odkaz:
https://doaj.org/article/9833565d720f4f38b70f3ee490440e10
Autor:
Gregory D. Scott, Moriah R. Arnold, Thomas G. Beach, Christopher H. Gibbons, Anumantha G. Kanthasamy, Russell M. Lebovitz, Afina W. Lemstra, Leslie M. Shaw, Charlotte E. Teunissen, Henrik Zetterberg, Angela S. Taylor, Todd C. Graham, Bradley F. Boeve, Stephen N. Gomperts, Neill R. Graff-Radford, Charbel Moussa, Kathleen L. Poston, Liana S. Rosenthal, Marwan N. Sabbagh, Ryan R. Walsh, Miriam T. Weber, Melissa J. Armstrong, Jee A. Bang, Andrea C. Bozoki, Kimiko Domoto-Reilly, John E. Duda, Jori E. Fleisher, Douglas R. Galasko, James E. Galvin, Jennifer G. Goldman, Samantha K. Holden, Lawrence S. Honig, Daniel E. Huddleston, James B. Leverenz, Irene Litvan, Carol A. Manning, Karen S. Marder, Alexander Y. Pantelyat, Victoria S. Pelak, Douglas W. Scharre, Sharon J. Sha, Holly A. Shill, Zoltan Mari, Joseph F. Quinn, David J. Irwin
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
The Lewy Body Dementia Association (LBDA) held a virtual event, the LBDA Biofluid/Tissue Biomarker Symposium, on January 25, 2021, to present advances in biomarkers for Lewy body dementia (LBD), which includes dementia with Lewy bodies (DLBs) and Par
Externí odkaz:
https://doaj.org/article/e84d47ecb7c4440da3c49a05adb2450e
Autor:
Madeleine E. Hackney, Allison A. Bay, Jordan M. Jackson, Joe R. Nocera, Venkatagiri Krishnamurthy, Bruce Crosson, Marian L. Evatt, Jason Langley, Xiangqin Cui, J. Lucas McKay, Daniel E. Huddleston
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Parkinson's disease (PD), an intractable condition impairing motor and cognitive function, is imperfectly treated by drugs and surgery. Two priority issues for many people with PD are OFF-time and cognitive impairment. Even under best medical managem
Externí odkaz:
https://doaj.org/article/611236b6f84a4fce9c227d9807396bbc
Autor:
Naying He, Jason Langley, Daniel E. Huddleston, Shengdi Chen, Pei Huang, Huawei Ling, Fuhua Yan, Xiaoping Hu
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102391- (2020)
Background: To date there are no validated MRI biomarkers to assist diagnosis of Parkinson’s disease (PD). Our aim was to investigate PD related iron changes in the substantia nigra pars compacta (SNpc) as defined by neuromelanin-sensitive MR contr
Externí odkaz:
https://doaj.org/article/861680a5b0944a32a0d123288d226c02
Publikováno v:
Brain Connect
Brain connectivity, vol 12, iss 3
Brain connectivity, vol 12, iss 3
Introduction: Locus coeruleus (LC) is the primary source of norepinephrine to the brain and its efferent projections innervate many brain regions, including the thalamus. LC degrades with normal aging, but not much is known regarding whether its stru
Autor:
John N. Makaryus, Haisam Ismail, Nicholas Chan, Amgad N. Makaryus, Daniel E. Huddleston, John N. Catanzaro
Publikováno v:
Cardiology in Review. 29:68-72
Muscular dystrophy has been an elusive term ever since it was first described in the 19th century. Introduced in 1891 by Wilhelm Heinrich Erb, muscular dystrophy has been classified as part of a larger group of genetically determined, progressive deg
Background Orthostatic hypotension (OH) is common in Parkinson disease (PD) and often coincident with cognitive impairment. The locus coeruleus (LC), a central autonomic and cognitive regulator, may be a common pathophysiologic link. Here we tested w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33715ba1b759327316fae488ef5757b8
https://doi.org/10.21203/rs.3.rs-936643/v1
https://doi.org/10.21203/rs.3.rs-936643/v1
Publikováno v:
Brain Communications
The loss of melanized neurons in the substantia nigra pars compacta is a primary feature in Parkinson’s disease. Iron deposition occurs in conjunction with this loss. Loss of nigral neurons should remove barriers for diffusion and increase diffusiv