Immunophenotyping to improve the mechanistic understanding of idiosyncratic drug-induced liver injury: clinical implications and future directions

Autor: Alejandro Cueto-Sánchez, Daniel E. Di Zeo-Sánchez, Antonio Segovia-Zafra, Gonzalo Matilla-Cabello, Ana Bodoque-García, María Isabel Lucena, Marina Villanueva-Paz

Publikováno v: Exploration of Digestive Diseases, Vol 2, Iss 2, Pp 56-76 (2023)

The late event onset of a fraction of idiosyncratic drug-induced liver injury (DILI) cases and the link observed by genome-wide association studies (GWASs) of certain human leucocyte antigen (HLA) alleles with DILI due to specific drugs support the c

Externí odkaz: https://doaj.org/article/376a91ad0efd4cadb235fdb15eb60000

P-33 EVALUATION OF CIRCULATING METABOLOME IN THE SEARCH OF POTENTIAL DRUG-INDUCED LIVER INJURY BIOMARKERS

Autor: Daniel E. Di Zeo-Sánchez, Inmaculada Medina-Cáliz, Judith Sanabria-Cabrera, Miren Garcia-Cortes, Aida Ortega-Alonso, Alejandro Cueto-Sanchez, Rocio San Juan-Jimenez, Andrés Gonzalez-Jimenez, Ismael Álvares-Álvarez, Hao Niu, Cristina Alonso, Guruprasad P Aithal, Raul J. Andrade, M. Isabel Lucena, Mercedes Robles-Diaz

Publikováno v: Annals of Hepatology, Vol 24, Iss , Pp 100397- (2021)

Introduction: Idiosyncratic drug-induced liver injury (DILI) is a complex hepatic condition whose diagnosis is challenging due to lack of specific biomarkers. Objectives: We aimed to evaluate serum metabolomic differences between patients with DILI a

Externí odkaz: https://doaj.org/article/67c0fc4d5644439b9b28339a3f5b6e57

Inclusion of dietary Ulva ohnoi 5% modulates Solea senegalensis immune response during Photobacterium damselae subsp. piscicida infection

Autor: M. Ángeles Esteban, C. Fernández-Díaz, Nora Albaladejo-Riad, Daniel E. Di Zeo, M. Carmen Balebona, F. Javier Alarcón, V. Anguis, Milena Fumanal, Miguel Ángel Moriñigo, Rocío Piñera

Publikováno v: Fish & Shellfish Immunology. 100:186-197

Macroalgae represent valuable sources of functional ingredients for fish diets, and the influence of supplemented aquafeeds on growth performance has been studied for some fish and seaweed species. In the present work, the potential immunomodulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bebdb136e0c0c1493eb947805c7429a
https://doi.org/10.1016/j.fsi.2020.03.007

FLIPPED CLASSROOM RESEARCH DURING COVID-19 PANDEMIC: A SCIENTOMETRIC OVERVIEW

Autor: Belén Delgado-Martín, Estefanía Caballano-Infantes, Carlos Sánchez-Gómez, Lorenzo G. Borrego, Isabel Brichette-Mieg, Daniel E. Di Zeo-Sánchez, Ana Dacil Marrero, Pablo Sánchez-Núñez, José Terrón-Bautista

Publikováno v: EDULEARN Proceedings.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0a6c5c6597be8e27366477fcda185e2
https://doi.org/10.21125/edulearn.2021.1828

Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction

Autor: Zeus Pérez-Valdés, Daniel E. Di Zeo-Sánchez, Eduardo García-Fuentes, Marina Villanueva-Paz, Raúl J. Andrade, M. Isabel Lucena, Carlos López-Gómez, Antonio Segovia-Zafra

Publikováno v: RIUMA. Repositorio Institucional de la Universidad de Málaga
instname
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3685-3726 (2021)
Acta Pharmaceutica Sinica. B

Idiosyncratic drug-induced liver injury (iDILI) encompasses the unexpected harms that prescription and non-prescription drugs, herbal and dietary supplements can cause to the liver. iDILI remains a major public health problem and a major cause of dru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36774e3ca9479447dcc96e8c18521ed
https://hdl.handle.net/10630/23614