Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Daniel E. Co"'
Autor:
Joshua P. Olorocisimo, Leomir A. Diaz, Daniel E. Co, Harold M. Carag, Joyce A. Ibana, Michael C. Velarde
Publikováno v:
Neuropharmacology. 225
Certain bacteria possess the ability to reduce anxiety- and stress-related behaviors through the gut microbiome-brain axis. Such bacteria are called psychobiotics, and can be used to improve mood and cognition. However, only a few bacteria have been
Autor:
Robert E. Hynds, Ariana Huebner, David R. Pearce, Mark S. Hill, Ayse U. Akarca, David A. Moore, Sophia Ward, Kate H. C. Gowers, Takahiro Karasaki, Maise Al Bakir, Gareth A. Wilson, Oriol Pich, Carlos Martínez-Ruiz, A. S. Md Mukarram Hossain, Simon P. Pearce, Monica Sivakumar, Assma Ben Aissa, Eva Grönroos, Deepak Chandrasekharan, Krishna K. Kolluri, Rebecca Towns, Kaiwen Wang, Daniel E. Cook, Leticia Bosshard-Carter, Cristina Naceur-Lombardelli, Andrew J. Rowan, Selvaraju Veeriah, Kevin Litchfield, Philip A. J. Crosbie, Caroline Dive, Sergio A. Quezada, Sam M. Janes, Mariam Jamal-Hanjani, Teresa Marafioti, TRACERx consortium, Nicholas McGranahan, Charles Swanton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Patient-derived xenograft (PDX) models are widely used in cancer research. To investigate the genomic fidelity of non-small cell lung cancer PDX models, we established 48 PDX models from 22 patients enrolled in the TRACERx study. Multi-regio
Externí odkaz:
https://doaj.org/article/15a9cb6171ca46d4a07fbfbe6bf74b76
Autor:
Rutulkumar Patel, Daniel E. Cooper, Kushal T. Kadakia, Annamarie Allen, Likun Duan, Lixia Luo, Nerissa T. Williams, Xiaojing Liu, Jason W. Locasale, David G. Kirsch
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Diverse tumor metabolic phenotypes are influenced by the environment and genetic lesions. Whether these phenotypes extend to rhabdomyosarcoma (RMS) and how they might be leveraged to design new therapeutic approaches remains an open question
Externí odkaz:
https://doaj.org/article/0569329ceb654b2aad711245a321df14
Autor:
Brent M. Roeder, Xiwei She, Alexander S. Dakos, Bryan Moore, Robert T. Wicks, Mark R. Witcher, Daniel E. Couture, Adrian W. Laxton, Heidi Munger Clary, Gautam Popli, Charles Liu, Brian Lee, Christianne Heck, George Nune, Hui Gong, Susan Shaw, Vasilis Z. Marmarelis, Theodore W. Berger, Sam A. Deadwyler, Dong Song, Robert E. Hampson
Publikováno v:
Frontiers in Computational Neuroscience, Vol 18 (2024)
ObjectiveHere, we demonstrate the first successful use of static neural stimulation patterns for specific information content. These static patterns were derived by a model that was applied to a subject’s own hippocampal spatiotemporal neural codes
Externí odkaz:
https://doaj.org/article/bae731737b054129adade7716064f04d
Autor:
Georgina Cornelio-Rodríguez, Enrique Álvarez-Arranz, Freddy Duarte-Rincones, Juan P. Reyes-González, Heriberto Hernández-Fraga, Daniel E. Córdova-Galván
Publikováno v:
Anales de Radiología, México, Vol 23, Iss 1 (2024)
Introducción: El empleo de hemodiálisis como tratamiento sustitutivo de la función renal es muy importante, ya que la insuficiencia renal es una complicación de múltiples patologías entre las que encontramos la diabetes y la hipertensión (prin
Externí odkaz:
https://doaj.org/article/e1035b07146c4cfbb2c02419555018e7
Autor:
Brooke E. Danielsson, Bobin George Abraham, Elina Mäntylä, Jolene I. Cabe, Carl R. Mayer, Anna Rekonen, Frans Ek, Daniel E. Conway, Teemu O. Ihalainen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Nuclear lamins have been considered an important structural element of the nucleus. The nuclear lamina is thought both to shield DNA from excessive mechanical forces and to transmit mechanical forces onto the DNA. However, to date there is n
Externí odkaz:
https://doaj.org/article/7d54aec06eb542c28e59f3f36e9dbf54
Autor:
Carl Delfin, Iulian Dragan, Dmitry Kuznetsov, Juan Fernandez Tajes, Femke Smit, Daniel E. Coral, Ali Farzaneh, André Haugg, Andreas Hungele, Anne Niknejad, Christopher Hall, Daan Jacobs, Diana Marek, Diane P. Fraser, Dorothee Thuillier, Fariba Ahmadizar, Florence Mehl, Francois Pattou, Frederic Burdet, Gareth Hawkes, Ilja C. W. Arts, Jordi Blanch, Johan Van Soest, José-Manuel Fernández-Real, Juergen Boehl, Katharina Fink, Marleen M. J. van Greevenbroek, Maryam Kavousi, Michiel Minten, Nicole Prinz, Niels Ipsen, Paul W. Franks, Rafael Ramos, Reinhard W. Holl, Scott Horban, Talita Duarte-Salles, Van Du T. Tran, Violeta Raverdy, Yenny Leal, Adam Lenart, Ewan Pearson, Thomas Sparsø, Giuseppe N. Giordano, Vassilios Ioannidis, Keng Soh, Timothy M. Frayling, Carel W. Le Roux, Mark Ibberson
Publikováno v:
Life, Vol 14, Iss 2, p 262 (2024)
Obesity is considered by many as a lifestyle choice rather than a chronic progressive disease. The Innovative Medicines Initiative (IMI) SOPHIA (Stratification of Obesity Phenotypes to Optimize Future Obesity Therapy) project is part of a momentum sh
Externí odkaz:
https://doaj.org/article/343e0c783d8e4fc48237db8466dd4363
Autor:
Likun Duan, Daniel E. Cooper, Grace Scheidemantle, Jason W. Locasale, David G. Kirsch, Xiaojing Liu
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Background 13C tracer analysis is increasingly used to monitor cellular metabolism in vivo and in intact cells, but data interpretation is still the key element to unveil the complexity of metabolic activities. The distinct 13C labeling patt
Externí odkaz:
https://doaj.org/article/434b833ee2984d61ad690e949b97ba6e
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 6, Pp n/a-n/a (2022)
Abstract The immunosuppressive agents sirolimus and everolimus are sensitive CYP3A4 substrates with narrow therapeutic index. Ritonavir is a strong CYP3A inhibitor. A phase 1 study was conducted to evaluate the pharmacokinetics, safety, and tolerabil
Externí odkaz:
https://doaj.org/article/0dfb66dcc061425485027c359f9261f7
Autor:
Brent M. Roeder, Mitchell R. Riley, Xiwei She, Alexander S. Dakos, Brian S. Robinson, Bryan J. Moore, Daniel E. Couture, Adrian W. Laxton, Gautam Popli, Heidi M. Munger Clary, Maria Sam, Christi Heck, George Nune, Brian Lee, Charles Liu, Susan Shaw, Hui Gong, Vasilis Z. Marmarelis, Theodore W. Berger, Sam A. Deadwyler, Dong Song, Robert E. Hampson
Publikováno v:
Frontiers in Human Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/cc536ae4ac8a4fb3974139891bbc17ea