Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Daniel E Michele"'
Autor:
Eric N Jimenez-Vazquez, Michael Arad, Álvaro Macías, Maria L Vera-Pedrosa, Francisco Miguel Cruz, Lilian K Gutierrez, Ashley J Cuttitta, André Monteiro da Rocha, Todd J Herron, Daniela Ponce-Balbuena, Guadalupe Guerrero-Serna, Ofer Binah, Daniel E Michele, José Jalife
Publikováno v:
eLife, Vol 11 (2022)
Background: Patients with cardiomyopathy of Duchenne Muscular Dystrophy (DMD) are at risk of developing life-threatening arrhythmias, but the mechanisms are unknown. We aimed to determine the role of ion channels controlling cardiac excitability in t
Externí odkaz:
https://doaj.org/article/3180e35d001a43e7a82ff755b7a2af96
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
Striated muscle has a highly ordered structure in which specialized domains of the cell membrane involved in force transmission (costameres) and excitation-contraction coupling (T tubules) as well as the internal membranes of the sarcoplasmic reticul
Externí odkaz:
https://doaj.org/article/975b340dbc124da8816601587161894d
Autor:
Cassandre Labelle-Dumais, David J Dilworth, Emily P Harrington, Michelle de Leau, David Lyons, Zhyldyz Kabaeva, M Chiara Manzini, William B Dobyns, Christopher A Walsh, Daniel E Michele, Douglas B Gould
Publikováno v:
PLoS Genetics, Vol 7, Iss 5, p e1002062 (2011)
Muscle-eye-brain disease (MEB) and Walker Warburg Syndrome (WWS) belong to a spectrum of autosomal recessive diseases characterized by ocular dysgenesis, neuronal migration defects, and congenital muscular dystrophy. Until now, the pathophysiology of
Externí odkaz:
https://doaj.org/article/798ef0f45e0e4478b76850bff3d09afd
Autor:
Feng Gu, E. Benjamin Randall, Steven Whitesall, Kimber Converso-Baran, Brian E. Carlson, Gregory D. Fink, Daniel E. Michele, Daniel A. Beard
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
The spontaneously hypertensive rat (SHR) is a genetic model of primary hypertension with an etiology that includes sympathetic overdrive. To elucidate the neurogenic mechanisms underlying the pathophysiology of this model, we analyzed the dynamic bar
Externí odkaz:
https://doaj.org/article/673ba72f27fc41bc8d642cb0753088f3
Autor:
Eric N Jimenez-Vazquez, Michael Arad, Álvaro Macías, Maria L Vera-Pedrosa, Francisco Miguel Cruz, Lilian K Gutierrez, Ashley J Cuttitta, André Monteiro da Rocha, Todd J Herron, Daniela Ponce-Balbuena, Guadalupe Guerrero-Serna, Ofer Binah, Daniel E Michele, José Jalife
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34e0614b6138a29dd3881fdf0a4dba40
https://doi.org/10.7554/elife.76576.sa2
https://doi.org/10.7554/elife.76576.sa2
Publikováno v:
FEBS J
Plasma membrane repair is an evolutionarily conserved mechanism by which cells can seal breaches in the plasma membrane. Mutations in several proteins with putative roles in sarcolemma integrity, membrane repair, and membrane transport result in seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb9eae6b8a20a15ca59624d8b5ba7d3
https://doi.org/10.1111/febs.15556
https://doi.org/10.1111/febs.15556
Autor:
Louis G. D'Alecy, Kaitlynn V. Bayne, Daniel E. Michele, Lauren E. Merz, Sara Schrade, Ashley J. Cuttitta, Kimber Converso-Baran, Steven E. Whitesall, Joanne F. Garbincius, Emily A. Armstead
Publikováno v:
Am J Physiol Heart Circ Physiol
Duchenne muscular dystrophy (DMD) is an X-linked disease caused by null mutations in dystrophin and characterized by muscle degeneration. Cardiomyopathy is common and often prevalent at similar frequency in female DMD carriers irrespective of whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1515aef69d522dba8d6e4ed60e132fd4
https://doi.org/10.1152/ajpheart.00333.2019
https://doi.org/10.1152/ajpheart.00333.2019
Autor:
Ki-Suk Kim, Diana M. Farris, Daniel E. Michele, Alfor G. Lewis, Youngsoo Kim, Matthew J. Sorensen, Robert T. Kennedy, Randy J. Seeley, Nadejda Bozadjieva, Steven E. Whitesall, Darleen A. Sandoval, Simon S. Evers
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 32, Iss, Pp 148-159 (2020)
Molecular Metabolism, Vol 32, Iss, Pp 148-159 (2020)
Objective Post–bariatric surgery hypoglycemia (PBH) is defined as the presence of neuroglycopenic symptoms accompanied by postprandial hypoglycemia in bariatric surgery patients. Recent clinical studies using continuous glucose monitoring (CGM) tec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::543ccf7ee0bc553948a94a3af3264d1f
https://doi.org/10.1016/j.molmet.2019.12.011
https://doi.org/10.1016/j.molmet.2019.12.011
Autor:
Eric N Jimenez-Vazquez, Michael Arad, Álvaro Macías, Maria Linarejos Vera-Pedrosa, Francisco M. Cruz-Uréndez, Ashley J Cuttitta, André Monteiro Da Rocha, Todd J Herron, Daniela Ponce-Balbuena, Guadalupe Guerrero-Serna, Ofer Binah, Daniel E Michele, José Jalife
Patients with cardiomyopathy of Duchenne Muscular Dystrophy (DMD) are at risk of developing life-threatening arrhythmias, but the mechanisms are unknown. We aimed to determine the role of cardiac ion channels controlling cardiac excitability in the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68ab7765059d586e874cbaff1f09e5db
https://doi.org/10.1101/2022.01.25.477696
https://doi.org/10.1101/2022.01.25.477696
Autor:
Lubna Willi, Ifat Abramovich, Jonatan Fernandez-Garcia, Bella Agranovich, Margarita Shulman, Helena Milman, Polina Baskin, Binyamin Eisen, Daniel E. Michele, Michael Arad, Ofer Binah, Eyal Gottlieb
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 9808
Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene and dilated cardiomyopathy (DCM) is a major cause of morbidity and mortality in DMD patients. We tested the hypothesis that DCM is caused by metabolic impairments by empl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18deaa922806473cb3d75bc127432b78
https://doi.org/10.3390/ijms23179808
https://doi.org/10.3390/ijms23179808