Výsledky vyhledávání - "Daniel Drocourt"

Akademický článek

Antiviral Activities of HIV-1-Specific Human Broadly Neutralizing Antibodies Are Isotype-Dependent

Autor: Blandine Noailly, Melyssa Yaugel-Novoa, Justine Werquin, Fabienne Jospin, Daniel Drocourt, Thomas Bourlet, Nicolas Rochereau, Stéphane Paul

Publikováno v: Vaccines, Vol 10, Iss 6, p 903 (2022)

Broadly neutralizing antibodies (bNAbs) offer promising opportunities for preventing HIV-1 infection. The protection mechanisms of bNAbs involve the Fc domain, as well as their Fab counterpart. Here, different bNAb isotypes including IgG1, IgA1, IgA2

Externí odkaz: https://doaj.org/article/4f3e8a4b09654c6ba1400f3a1405b1c8

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Akademický článek

Dectin-1 is essential for reverse transcytosis of glycosylated SIgA-antigen complexes by intestinal M cells.

Autor: Nicolas Rochereau, Daniel Drocourt, Eric Perouzel, Vincent Pavot, Pierre Redelinghuys, Gordon D Brown, Gerard Tiraby, Xavier Roblin, Bernard Verrier, Christian Genin, Blaise Corthésy, Stéphane Paul

Publikováno v: PLoS Biology, Vol 11, Iss 9, p e1001658 (2013)

Intestinal microfold (M) cells possess a high transcytosis capacity and are able to transport a broad range of materials including particulate antigens, soluble macromolecules, and pathogens from the intestinal lumen to inductive sites of the mucosal

Externí odkaz: https://doaj.org/article/88f2443e33b84649b846b4d2a4e28821

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Akademický článek

Innate immune response of alveolar macrophage to house dust mite allergen is mediated through TLR2/-4 co-activation.

Autor: Chia-Fang Liu, Daniel Drocourt, Germain Puzo, Jiu-Yao Wang, Michel Riviere

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e75983 (2013)

House dust mite, Dermatophagoides pteronyssinus (Der p), is one of the major allergens responsible for allergic asthma. However, the putative receptors involved in the signalization of Der p to the innate immune cells are still poorly defined as well

Externí odkaz: https://doaj.org/article/b3ebf6ce7daa452081311164c590277f

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Akademický článek

Anti-CD20 IgA can protect mice against lymphoma development: evaluation of the direct impact of IgA and cytotoxic effector recruitment on CD20 target cells

Autor: Virginie Pascal, Brice Laffleur, Arnaud Debin, Armelle Cuvillier, Marjolein van Egmond, Daniel Drocourt, Laurent Imbertie, Céline Pangault, Karin Tarte, Gérard Tiraby, Michel Cogné

Publikováno v: Haematologica, Vol 97, Iss 11 (2012)

Background While most antibody-based therapies use IgG because of their well-known biological properties, some functional limitations of these antibodies call for the development of derivatives with other therapeutic functions. Although less abundant

Externí odkaz: https://doaj.org/article/229e9afd88c64c1d9f457da071b1f191

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Rational design of adjuvants targeting the C-type lectin Mincle

Autor: Eric Perouzel, Alain Vercellone, Jacques Prandi, Martine Gilleron, Sandro Silva-Gomes, David Sancho, Jérôme Nigou, Francisco J. Cueto, Gérard Tiraby, Thierry Lioux, Sophie Barbe, Alexiane Decout, Daniel Drocourt, Isabelle André

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (10), pp.2675-2680. ⟨10.1073/pnas.1612421114⟩
Proceedings of the National Academy of Sciences of the United States of America 10 (114), 2675-2680. (2017)
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (10), pp.2675-2680. ⟨10.1073/pnas.1612421114⟩

Adresse actuelle Decout Alexiane : GLYcoDiag, Res Dept, F-45067 Orléans 2, France; The advances in subunit vaccines development have intensified the search for potent adjuvants, particularly adjuvants inducing cell-mediated immune responses. Identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56c225655bcba837d0dd6b0c3556392
https://doi.org/10.1073/pnas.1612421114

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Mycobacterium tuberculosis inhibits human innate immune responses via the production of TLR2 antagonist glycolipids

Autor: Olivier Neyrolles, Brigitte Gicquel, Mi-Seon Jang, Jacques Prandi, Landry Blanc, Priscille Brodin, Jérôme Nigou, Ok-Ryul Song, Alain Vercellone, Martine Gilleron, Gérard Tiraby, Daniel Drocourt

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (42), pp.11205-11210. ⟨10.1073/pnas.1707840114⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (42), pp.11205-11210. ⟨10.1073/pnas.1707840114⟩

Mycobacterium tuberculosis is a major human pathogen that is able to survive inside host cells and resist immune clearance. Most particularly, it inhibits several arms of the innate immune response, including phagosome maturation or cytokine producti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d87f356246c3a25367241bb406b36576
https://hal.science/hal-03178071

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Le navire romain de Marseille: une première mondiale

Autor: Myriame Morel-Deledalle, Daniel Drocourt

Publikováno v: Museum International (Edition Francaise). 35:49-53

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d61ac2394f85d2ff1df6a0159ded9726
https://doi.org/10.1111/j.1755-5825.1983.tb00833.x

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IgG1 Allotypes Influence the Pharmacokinetics of Therapeutic Monoclonal Antibodies through FcRn Binding

Autor: David Ternant, Christophe Passot, Christine Dhommée, Gilles Paintaud, Gérard Tiraby, Christophe Arnoult, Valérie Gouilleux-Gruart, Daniel Drocourt, Nadine Baroukh, Eric Perouzel, Hervé Watier, Martine Pugnière, Denis Mulleman

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2016, 196 (2), pp.607-613. ⟨10.4049/jimmunol.1501780⟩

Because IgG1 allotypes might have different half-lives, their influence on infliximab (G1m17,1 allotype) pharmacokinetics was investigated in a group of spondyloarthritis patients. Infliximab was found to have a shorter half-life in patients homozygo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b11a1768d70c899e5f0737fe172318
https://pubmed.ncbi.nlm.nih.gov/26685205

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Concomitant expression ofE. colicytosine deaminase and uracil phosphoribosyltransferase improves the cytotoxicity of 5-fluorocytosine

Publikováno v: FEMS Microbiology Letters. 167:41-49

The prodrug activation system formed by the E. coli codA gene encoding cytosine deaminase (CD) and 5-fluorocytosine (5-FC) developed for selective cancer chemotherapy suffers from a sensitivity limitation in many tumour cells. In an attempt to improv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f8a3c577e52a914451ee5c5ac4a45b
https://doi.org/10.1111/j.1574-6968.1998.tb13205.x

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Dectin-1 is essential for reverse transcytosis of glycosylated SIgA-antigen complexes by intestinal M cells

Autor: Pierre Redelinghuys, Bernard Verrier, Xavier Roblin, Nicolas Rochereau, Gérard Tiraby, Vincent Pavot, Gordon D. Brown, Blaise Corthésy, Stéphane Paul, Daniel Drocourt, Christian Genin, Eric Perouzel

Publikováno v: PLoS Biology
PLoS Biology, Vol 11, Iss 9, p e1001658 (2013)
PLoS Biology, Public Library of Science, 2013, 11 (9), pp.e1001658. ⟨10.1371/journal.pbio.1001658⟩
PLoS Biology, vol. 11, no. e1001658, pp. 1-18
Europe PubMed Central
PLoS Biology, 2013, 11 (9), pp.e1001658. ⟨10.1371/journal.pbio.1001658⟩

This work reports the long-awaited identification of Dectin-1 and Siglec-5 as the M cell co-receptors that mediate the reverse transcytosis of secretory IgA molecules to mount a gut immune response.
Intestinal microfold (M) cells possess a high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75e6672a29b3a81a42d019f2e6d0df4
https://pubmed.ncbi.nlm.nih.gov/24068891

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